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Valium
Antianxiety/ Benzo
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Ativan
Antianxiety/ Benzo
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Versed
antianxiety/ Benzo
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Haldol
antipyschotic/ Typical
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Zyprexa
antipsychotic/ atypical
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Risperdal
antipsychotic/ atypical
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Abilify
antipsychoti/ atypical
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nardil
antidepressant/ MAOI
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Prozac
antidepressant SSRI
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Zoloft
antidepressant/ SSRI
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Celexa
antidepressant SSRI
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Wellbutrin
antidepressant
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Tegretol
anticonvulsant (mood stabilizing)
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Depakote/ Depakene
anticonvulsant - mood stabilizing
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Neurontin
anticonvulsant- mood stabilizing
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Klonopin
- anticonvulsant/ antianxiety/ benzo
- mood stabilizing
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what is the action of Benzodiazepnes?
thought to potentiate the effects of GABA (a powerful inhibitory NT) thereby producing a calming effect
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Non Benzo antianxiety agent?
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action of SSRI?
selectively inhibits the CNS neuronal uptake of serotonin (5HT)
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action of anticonvulsants and what group does it belong to ?
- treats bipolar disorder, action is unclear
- mood stabilizing
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Xanax, Valium, Ativan are examples of
Benzos or antianxiety agents increasing the effects of GABA producing a calming effect
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Klonopin
anticonvulsant, antianxiety, benzo, mood stabilizing
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Prozac, Zoloft are used as
antidepressants SSRI
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Lithium (Escalith)
- mood stabilizing
- alters Na++in brain, lithium levels needed, controls mania symptomslow Na+ diet, fluids, polyuria
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Tegretol, Depakote, Depakene, Neurontin are
anticonvulsants (mood stablizing)
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what are Extrapyramidal symptoms?
acute adverse effects of an antipyschotic drug, most common are tremors, rigidity and dystonic reactions
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pseudoparkinsonism
tremors, mask like facial expressions, rigidity, drooling loss of assoc movements of arms and some restlessness
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dystonia
muscle rigidity, abnormal posturing, protrusion of tongue, mandibular movements
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akathesia
motor restlessness
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MAOI- antidepressants are last line why? and name 2.
- Major SE, GI (tyramine) needs special low tyramine diet
- Nardil
- Parnate
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typical (older) antipyschotics
Thorazine, Mellaril, Prolixin, Stelazine, Navane, Haldol,
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Atypical (newer) antipyschotics
- Clozaril
- Zyprxia
- Seroquel
- Resperdal
- can cause EPS
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considerations for antipyschotics
- produce calming effects w/out sedating
- controls "positive" symptoms
- no tylenol (interacts with drugs that affect liver detoxifcation)
- EPS symptoms, NMS, monitor WBC with Clozaril
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Antidepressant categories
- Tricyclics- affect reabsorption of Nor Epi and Seratonin (risk of OD)
- SSRI's blocks reabsoprtion of Serotonin (take in AM)
- MAOI (last line) blocks MAO needed to metabolize nor epi, seratonin and dopamine. Low tyramine diet
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beta blocker for anti anxiety?
Inderal (propanolol)
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Anti-anxiety
- action: blocks GABA causes sedation
- can be abused, pysical dependance, intentional OD
- Dont stop Benzos abruptly
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most important pharmacolocig characteristics of antipyschotic drugs are:
- 1. ability to calm aggresive pts
- 2. failure of large doses to produce deep coma
- 3. production or reversible or irreversible effects on the EP system
- 4. lack of notable tendency to produce physical dependance
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difference of antianxiety and antipyschotic?
antianxiety no EPS
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