Myasthenia gravis

  1. What are some exacerbation triggers for MG?
    • Infection
    • Stress
    • Fatigue
    • Heat
  2. What is the tensilon test for?
    • Reveals improved muscle contractility.
    • Also aids in dx of cholinergic crisis
  3. Myasthenia Gravis is?
    Progressive autoimmune disease that produces severe muscular weakness, with periods of exacerbation and remission
  4. Causes of MG
    • Co-existing autoimmune disorder
    • Strong association with hyperthyroidism
    • Hyperplasia of the thymus
  5. What is plasmapheresis?
    Removal of circulating antibodies by a process thay removes antibodies from plasma
  6. Thymectomy
    Removal of thymus
  7. What are s/s to monitor for?
    • Progressive muscle weakness
    • Poor posture
    • Ptosis
    • Dysphagia
    • Diplopia
    • Resp compromise
  8. For MG you are going to assess/monitor for?
    • Resp status
    • Swallowing ability(aspiration)
    • Muscle srength
    • Med hx
  9. What are some nursing diagnosis for MG?
    • Ineffective airway clearance
    • Ineffective breathing patrern
    • Self care deficit
    • Impaired physical mobility
    • Imbalanced nutrition:less than
    • Constipatiob
    • Impaired verbal commumication
  10. What are some medications used for MG?
    • Immunosuppressants (imuran, cytoxan & prednisone)
    • IV immuniglobulins
    • Cholinesterase inhibitor (mestinon- pyridostigime)
    • Eat within 45min to strengthen chewing and reduce aspiration
  11. Undermedication in MG is called? What are the characteristics?
    • Myasthenia crisis
    • Resp muscle weakness(mechanical ventilation)
    • Myasthenic symptoms(weakness, incontinence, fatigue)
    • HTN
    • Temporary improvement of symptoms with tensilon
  12. What is overmedication in MG called? What are some characteristics?
    • Cholinergic crisis
    • Muscle twitching to the point of resp muscle weakness(mechanical ventilation)Cholinergic symptoms(hypersecretions, nausea, diarrhea, resp secretions and hpermotility[abd cramps])
    • Hypotension
    • Tensilon has no positive effects, may worsen then give atropine
  13. Muscles that are most often involved in MG?
    The ones used for blinking, swallowing, speaking and breathing. These are controlled in the brainstem
  14. How to test for muscle weakness?
    Have the client loom up for 2-3 min, if the clint has MG the eyelids will start to droop. After rest client can hold eyes open again
  15. What are the signs symptoms of MG crisis?
    • Tachycardia
    • Tachypnea
    • HTN
    • Cyanosis
    • Anoxia
    • B/b incontinence
    • Decreased urinary out
    • Absent cough or swallowing reflex
  16. What are the s/s of cholinergic crisis?
    • N/v
    • Diarrhea
    • Abd pain
    • Pallor
    • Blurred vision
    • Hypotension
    • Pupillary miosis
    • Facial twitching
Card Set
Myasthenia gravis
Unit 5 exam