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What's special about Pancreatic Cancer?
Trosseau's Syndrome = Migratory Thrombolembolism secondary to Pancreatic Cancer (redness and tenderness on palpation of extremities)
- Poor prognosis; usually already met-ed on presentation.
- Pancreatic head cancer causes obstructive jaundice
- Remember Tumor Marker is CA-19-9! Wish stephanie had lived to be 199, but she first had problems with her pancreas
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Rule of 9s for burn evaluation.
Know it.
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Where does leischmaniasis live
Inside macrophages/monocytes.
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Which of the three adrenal cortex hormones is not controlled at all by ACTH?
Zona Glomerulosa - Aldosterone!
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What is considered a positive Western Blot for HIV?
- need positive for 2 out of the 3 enzymes which are...
- p24 (capsid protein)
- gp41 (fusion and entry)
- gp121 (attachment to t-cell)
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Where do Munro Microabcesses occur?
Psoriasis
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Conn syndrome?
- Hyperaldosternism
- from adenoma of adrenal gland
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Diabetic Retinopathy versus Roth Spots
- Diabetic Retinopathy = Cotton Wool Spots with Macular Edema
- Roth Spots = Round white sponts on retina with hemorrhage
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Difference between DHEA and DHEAS
- DHEA = Product of 17 alpha hydroxylase
- DHEAS = Inactive product of Cortisol breakdown.
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Sign of Premature Menopause
Reduced Inhibin Levels
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What disease will give you a false + on syphilus tests?
- SLE. Due to antiphospholipid antibodies.
- This also explains why people with SLE although hypercoaguable can show long PTT, it's because antibodies react to phospholipids used in that reaction.
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What is Lichen Planus?
- Purple, Polygonal, Pruritic, Papules. Sawtooth infilitrate of lymphocytes at dermal-epidermal junction.
- ASSOCIATED WITH HEP C. Usually self-resolves.
- T-cell mediated.
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What is erythema nodosum associated with?
- Coccidioidomycosis
- Histoplasmosis
- TB
- leprosy
- STrep
- Sarcoidosis
Inflammatory lesion of SC fat on anterior shin.
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Pityriasis Rosea
"Herald Patch" Solitary pink / flesh colored path on otherwise healthy adolescent or young adult.
Followed by "Christmas tree" papules and plaques on trunk and upper extremities several days later.
Self-resolving. Viral etiology.
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Different effects of Aspirin at different doses
- Low does (<300 mg) = decreases platelet aggregation
- Med. Dose (<300-2400mg) = Anti-pruritic, analgesic
- High dose 2400-4000 mg = Anti-inflammatory.
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Why can NSAIDS cause renal damage?
- They block the action of Prostaglandins, which dilate the afferent arteriole
- This increases RPF and GFR (but keeps FF constant)
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Suffix for bisphosphonates?
- -dronate!
- Inhibits osteoclast activity!
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What is the difference between etanercept and infliximab/adalimumab?
- Infliximab and adalimumab are Anti-TNF-alpha antabodies
- while
- etanercept is a TNF-alpha receptor decoy!
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What does Teres Major always go with?
- Latissimus Dori
- Note that Teres Major is Innervated by lower subscapular
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Difference between flexor digitorum profundis and superficiales
Flexor Digitorum Profundis = All Jts. Separated Median/Ulnar nerve.
- Flexor Digitorum Superficiales = MCP and PIP
- Only Median Nerve.
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