The diagram shows the reversible conversion of pyruvate to lactate by the enzyme lactate dehydrogenase.
What would the effect of inhibition of lactate dehydrogenase in a mammalian cell under anaerobic conditions?
1) A decrease in glycolysis due to lack of NAD
2) A decrease in cell pH due to the accumulation of lactic acid
3) An increase in ATP production due to increased amounts of reduced NAD
4) An increase in the activity of the Krebs cycle due to increased amount of pyruvate.