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Maternal mortality rate?
- 8 women deaths out of 100,000 live births due to hypertension (eclampsia)
- causes: hemorrhage, gestational hypertension, embolism
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Infant mortality rate?
- 7 out of 1000 live births
- US is 29th in the world
- 6/1000 white infants, 14/1000 black infants
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Adolescent pregnancy
- 54/1000 between 15-19 yrs old
- 3 out of 10 teens will be pregnant before age 19
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infertility issues
- 20% of all women have infertility issues
- decreased fertility due to STIs and scarring
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Access to care
Only 60% of women get prenatal care
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Conception and fetal development
- Union of mature ovum and sperm equal human life
- Ovum=22 autosomes+XX(sex)=23
- Sperm=22 autosomes+XY(sex)=23
- Ova are viable for 24 hours after ovulation
- Sperm are viable for 72 hours after ejaculation
- Fertilization takes place in ampulla's of fallopian tube
- Scarring in the tube prevents the sperm form getting to the egg
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Zygote
new cell formed when egg is fertilized
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Intrauterine development
- Union of ovum and sperm-zygote (1st week)
- 16 cells-morula (60 hours later)
- morula attaches to uterine wal (4 days later)
- best place for the morula to attach is the fundal area on top of the uterus because we want the baby to come out first then the life line second.
- need uterine muscle at the top to contract to keep from bleeding to death
- Placenta previa-zygote settling at the bottom of the uterus
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tropoblasts and embroblasts
- 99 tropoblasts forms all supportive structures
- 8 embroblasts froms embryo and eventually the fetus
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human chorionic gonadotropin (hCG)
- zygote secretes hCG which stimulates the corpus luteum of the ovary to remain viable and continue to secrete progesterone for 4 to 12 weeks to secure the pregnancy.
- prevents normal involution of the corpus luteum at the end of menses
- if corpus luteum ceases functioning before 11th week of pregnancy-spontaneous abotion occurs
- in male fetus, it stimulates testes to produce testosterone which causes male sex organs to grow.
- Bases for all pregnancy tests
- Cause of morning sickness (6-12 weeks) 50% of women experience morning sickness
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Progesterone
- valium of pregnancy causes profuse vasodilation to calm down contractions
- causes edometrium to change into the decidua which provides nourishment for the embryo
- reduces uterine contraction, thus preventing spontaneous abortions
- drop in progesterone causes early miscarriages
- BP is lowered because vessels are dilated, if BP goes up it is abnormal
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Placenta
- Formed by the end of the 12th week and takes over the responsibility of producing progesterone and other needed hormones
- Thick, disk-shaped organ whose major function are 1. metabolic, 2. transfer of substances between mother and fetus and, 3. endocrine
- 1/6th of weight and the end of a term pregnancy
- total surface area of a full term placenta is 15 square yards
- Maternal side is red, flesh like
- Fetal side is shiny gray-white with vessels visible
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Human Placental Lactogen (hPL)
- promotes normal nutrition and growth of fetus
- prepares maternal breast development for lactation
- facilitates transport of glucose across the placenta by diffusion, active transport, and pinocytosis
- production increases progressively during 2nd half of pregnancy
- decreases maternal insulin sensitivity and utilization of insulin (an insulin antagonist)
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estrogen (estriol)
- causes enlargement of the women's uterus, breast and external genitalia
- increases vascularity to reproductive organs
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Amniotic fluid
- provides a protective environment for fetus
- clear fluid surrounds baby in utero
- provides stable temperature surrounding fetus (98.6)
- allows rooom and buoyancy for fetal movement
- derives from fetal urine and fluid transported from maternal blood across the amnion.
- exchanged constantly everyday
- volume increases during pregnancy-should have 1000ml at term
- characteristics-98% water, alkaline 2% organic solids, clear in color
- Green-meconium; red-bleeding; cloudy-infection-; amber-bilirubin
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embryonic period-conception to 8 weeks gestation
- differentiation of ceels and rapid growth
- rudimentary body parts formed
- heart has four chambers and begins beating
- beginning of all major body structure
- external genitalia present-no gender yet
- some movement by limbs
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third month (9-12 weeks)
- eyelids fused; nail beds formed
- teeth and bones begin to appear
- kidneys begin to function-amniotic fluid
- begins to swallow
- grasps, sucking and withdrawal reflexes present
- gender distinguishable
- downy lanugo begins development
- normally women do not know they are pregnancy during this time
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fourth month (13-16 months)
- much spontaneous fetal movement
- moro reflex present
- rapid skeletal development
- meconium present in GI tract
- uterine development in female
- lanugo (fine hair) appears over body
- quickening-fetal movement felt by mom
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fifth month (17-20 weeks)
- eyebrown and head hair appears
- skeleton begins to harden
- permanent tooth bud appear-tetracyclin discolor infant teeth
- vernix caseosa appears-surround fetus, thick lotion to preserve skin
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six months (21-24 weeks)
- miniature baby in appearance
- extra uterine life possible
- skin has red, wrinkled appearance
- responds to external sounds
- fetus is very active
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seventh month (25-28 weeks)
- eyelids are no longer fused
- testes begin to descend into scrotum for males
- assumes head-down position in uterus
- respiratory-like movement detected
- subcutaneous fat is being deposited under skin
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eighth month (29-32 weeks)
- begins to store fat and minerals
- lanugo disappears from the face
- skin loses reddish color
- exhibits good reflex developent
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ninth and tenth month (33-40 weeks)
- fetal body begins to round out
- increas of iron storage by liver
- ear cartilage firm on both ears
- lanugo and vernix caseosa disappear
- high absorption of maternal hormones
- ready for birth
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fetal circulation
- 1 umbilical vein brings in oxygenated blood via the placenta
- 2 umbilical arteries bring deoxygenated blood back to the placenta
- SpO2 is 40-45% for fetus
- fetal lungs and liver functions are from the placenta
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three unique fetal structures
- ductus venosus-bypasses liver to inferior vena cava
- foramen ovale-shunts blood from R to L heart
- ductus arteriosis-bypasses lungs-brings blood to the brain the quickest
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abortion
termination of pregnancy prior to 20th week gestation
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term
the normal duration of pregnancy 38-40 weeks
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preterm labor
occurs after 20 weeks, before 30 weeks
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post term labor
after 42 weeks
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still birth
- fetus born dead after 20 week gestation
- diabetes is a big risk factor
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gravida
any pregnancy regardless of duration, including present one
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primigravida
a woman who is pregnant for the first time
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multigravida
a woman who is in her second or subsequent pregnancy
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nulligravida
a woman who has never been pregnant
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parity
number of pregnancies that have reached viability, regardless of whether the infant was alive or stillborn
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primipara
a woman who has have one birth greater than 20 weeks regardless of whether the infant is born alive or dead
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multipara
2 births greater than 20 weeks
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Estimated Date of Birth
- Nageles rule: 1st day of last normal menstrual period (LNMP) subtract 3 months add 7 days and 1 year
- 90% of women will deliver +/-2 weeks of estimated date
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fundal height
- top of uterus
- indicated uterine size by measuring from the top of the symphysis pubis to the top of the fundus
- correlates with weeks of gestation between 20-30 weeks
- order ultrasound, if it does not correlate
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Alpha-fetoprotein (AFP)
- predominant protein in fetal plasma
- can be measured in both maternal serum and in amniotic fluid
- increased levels-indicate open neural tube defects
- decreased levels-could indicate down syndrome, molar pregnancy
- test is done between 15-18 weeks gestation
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glycosylated hemoglobin (Ghb A1C)
- minor hemoglobin with glucose attached
- previous 90 days of blood sugar and measurement of glycemic control
- levels of 6 or less: measured from 1-15, 15 i out of control, 6 or less is controlled
- When baby is exposed to high blood glucose levels in first trimester, baby will most likely have cardiac anomalies
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prenatal visits
- Every 4 weeks until 28 weeks
- Every 2 weeks up to 36 weeks
- Every week after 36 weeks
- More frequent for high risk
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uterus
- goes from 2oz to 2 lbs at term
- increase in size due to hypertrophy of myometrium cells under estrogen influence
- 1/6 of total masternal blood volume is contained within the vascular system of the uterus by term
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cervix
- estrogen causes the cervix to become congested with blod, resulting in a bluish color that extends to include the vagina-Chadwick's sign
- increased vascularity causes the cervix to soften-Goodell's sign
- Increased mucus forms the mucus plug to seal off the cervix from outside bacteria
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ovaries
- cease ovum production during pregnancy
- corpus luteum persists til 12 weeks to secrete progesterone til the placenta takes over
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vagina
- increased vasculaity and hyperplasia
- increased vaginal secretion and decrease in pH to prevent infections
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breasts
- increase in size and nodularity to prepare for lactation
- nipples increase in size, become more erect and more pigmented
- colostrum-an antibody rich, yellow fluid can be expressed after the 12th week. it converts to mature milk after delivery
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respiratory system
- oxygen consumption increases by 15-20%
- tidal volume increases 40%
- by the third trimester, the diaphragm is lifted 1.5inches which prevents the lungs from expanding fully
- breath becomes thoracic rather than abdominal in nature
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cardiovascular system
- 45% increase in blood volume which peaks in the 7th month
- 30% increase in total RBC volume (mostly plasma) which causes the hemodilution of pregnancy in the second trimester
- decrease in BP due to decreased peripheral vascular resistance
- WBCs increase throughout gestation
- 12-15 WBC is normal for pregnant women
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GI system
- reflux of gastric contents common due to relaxation of smooth muscles by progeserone
- ptyalism (excessive salivation) is a common condition of pregnant women
- decreased in intestinal motility-constipation
- nausea and vomiting (morning sickness) is due to high hCG levels from 6-12 weeks
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renal system
- 50% increase in glomerular filtration rate
- kidneys and ureters dilate due to high progesterone levels
- glycsuria is common during pregnancy due to kidney's inability to absorb all the glucose filter by the glomeruli. this environment increases the risk of UTIs during pregnancy
- UTIs can lead to preterm labor
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integumentary system
- increase in activity of sweat and sebaceous glands-perspiration and acne
- hyperpigmentation-chloasma or mask of pregnancy darkens forehead, cheeks and nose
- linea nigra-dark line of pigmentation from umbilicus to the symphysis pubis
- striae (stretch marks) occur on abdomen, breasts, and thighs as pregnancy progresses
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metabolism
- BMR increases to support the additional demands of the growing fetus
- 25-35 lbs is the average weight gain during a single pregnancy
- increase in water retention of 7 liters of water by term
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subjective changes
- amenorrhea-earliest symptom of pregnancy
- nausea and vomiting-50% of women experience this
- excessive fatigue-presents in 1st trimester
- urinary frequency-common during 1st and 3rd trimester due to uterine pressure
- breast tenderness-due to growth
- quickening-fetal movement felt by mother
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objective changes
- Goodell's sign-softening of the cervix
- Chadwick's sign-bluish coloration or cervix
- Hegar's sign-softening of isthmus
- Abdominal enlargement-uterine growth
- Pigmentation of skin-occurs in 50%
- palpation of fetal outline-greater than 24 weeks
- Ballottement-passive fetal movement
- Positive pregnancy test-hCG present
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Diagnostic changes of pregnancy
- fetal heart beat-110 to 160 bpm
- fetal movement-palpated by trained examiner greater than 20th week gestation
- ultrasound-fetal outline detected
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physiological response to pregnancy
- ambivalence-initial response, no visible body change yet
- acceptance-triggered by quickening in 2nd trimester
- introversion-turning in on one's self
- mood swings-from great joy to despair
- body image change-the picture of your body you have of yourself
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common discomforts of pregnancy
- morning sickness-eat 4-5 crackers at the bedside, eat protein meal at the end of night
- urinary frequency-stop caffeine, no sugar
- vaginal discharge-shower twice a day
- heartburn-smaller more frequent meals, tums, no lying down 2 hours after you eat
- hemorrhoids-fiber, witch hazel tucks
- leg cramps-dorsiflex, bananas, calcium
- backache-flat shoes, posture
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ultrasound
- sound waves bounce off densities to form picture
- measures bi-parietal diameter, femur length, and crown to rumb length to determine gestational age
- localize placenta
- identifies fetal anomalies
- validates suspected multiple pregnancies
- evaluates amniotic fluid
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alpha-fetoprotein screening
- predominate protein in fetal plasma; excreted in fetal urine into amniotic fluid
- test is run between 15-18 weeks gestation
- if abnormal results return-amniocentesis is done
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amniocentesis
- aspiration of amniotic fluid for analysis of chromosomal abnormalities, blood incompatibility and determin fetal maturity
- to determine fetal lung maturity: detects lecithin/sphinogomyelin ratio that make up surfactant; a ratio of 2:1 indicates surfactant is adequate at 35 weeks
- to determine fetal hemolytic disease-bilirubin concentration: levels of bilirubin in amniotic fluid reflects the amount of fetal RBC destruction that had taken place
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indications for amniocentesis
- maternal age of 35 or above
- previous genetic disorder
- altered chromosomal pattern (trisomy 21)
- history of 3+ spontaneous abortions
- elevates MS-AFP level
- history of neural tube defects
- usually performed between 15-17 weeks
- tissue cultures must be grown for several weeks, thus results aren't available immediately
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complications of amniocentesis
- uterine infection
- spontaneous abortion
- PROM-premature rupture of membranes
- fetal injury
- placental abruption
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Chorionic villus sampling (CVS)
- alternative to amniocentesis which can be done earlier
- usually performed between 10-12 weeks
- developing placenta is biopsied via transvaginally or abdominally under ultrasound guidance
- complications-spontaneous loss
- greatest benefit is the option to terminate
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conditions that accelerate or increase l/s ratio sooner
- premature rupture of membranes
- hypertension disease
- prolonged rupture of membranes
- placental insufficiency
- all these things causes stress to the baby which secretes cortisol and cortisol increases surfactant production.
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conditions that delay l/s ratio
- diabetes
- nonhypertensive glomerulonephritis
- blood incompatibilities
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fetal movement count (FMC)
- daily maternal assessment of fetal activity by counting the number of fetal movement within a specified time period
- usually starts at 28 weeks for high risk
- side lying position utilized after eating a meal
- a count of 3+ movement/hour needs further evaluation
- is a non-invasive no cost method to evaluate fetal well being in last trimester of pregnancy
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nonstress test
- assesses fetal well being by evaluating FHR acceleration in association with fetal movement
- FHR accelerations indicate adequate oxygenations, a healthy CNS, and the ability of the fetal heart to respond to stimuli
- procedure: client is placed in semi-fowlers position, an external fetal monitor is applied, a baseline strip is obtained, fetal movement indicated by the mother, interpretation reactive 2 accelerations/10 minutes 15bpm lasting 15 seconds
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contraction stress test (CST)
- is used to identifty the fetus at risk for intrauterine hypoxia by observing the response o the FHR to contraction
- if fetal hypoxia is demonstrated-late decelerations
- FHR and patterns are evaluate in response to contractions (stress)
- Methods: nipple stimulation to produce 3 contractions within a 10 minute period
- interpretation: 50% late decelerations with contractions in 10 minute is a problem
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Biophyisical profile assess 5 parameters+NST
- FHR
- fetal breathing
- gross fetal movement
- fetal tone
- amniotic fluid volume
- criterion: up to 10 points are assigned
- each parameter is either present=2 or absent=0
- 8-10 points is normla
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Fetal heart rate
- use leopold maneuvers to identify the best postion to locate the transducer to hear the loudest FHR
- usually heard the loudest through the fetal back
- typically found in the mother's lower quadrant on left side if fetus is in a LOA position
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Baseline changes
- tachycardia 160bpm+for 10 minutes
- in prematurity, chronic fetal hypoxia, maternal fever (#1 reason), fetal anemia
- bradycardia 110 or below bpm for 10 minutes
- in fetal hypoxia, maternal drugs, compressed cord, maternal supine position (convenient for HCP)
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early decelerations
- fetal head compression
- mirrors the contraction below
- begins and ends with the contraction below
- FHR usually stays within normal range
- generally benign and seen in late labor
- head compression stimulates vagus nerve to slow HR
- no interventation considered category 1, benign
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late decelerations
- due to uteroplacental insufficiency (UPI) causes by being on back, baby isnt getting oxygen
- onset is late-after peak of contraction
- tend to occur with every contraction
- degree of fall doesnt reflect insufficiency
- usually goes below normal range
- Interventions: turn client to left side, give oxygen, increase IV
- turn pitocin off if infusing
- document and report observations
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variable deceleration
- due to cord compression
- FHR goes below normal range
- deceleration dont have a uniform shape
- they fall and rise abruptly
- occurs at times unrelated to contractions
- interventions: change maternal position, C-section if can't change pattern within 30 minutes
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interpretation of fetal HR patterns: Category 1
- predictive of normal acid base balance
- accelerations with fetal movements
- no periodic changes to baseline
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Category 2
- tracings are indeterminate and not predictive
- tachycardia or bradycardia
- minimal or absent variability
- late or variable decelerations
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category 3
- tracings are abnormal
- predictive of abnormal acid base status
- absent baseline variability
- recurrent late and/or variable decelerations
- requires prompt evaluation and interventions:
- maternal oxygen
- changes in maternal position
- discontinue pitocin
- treatment of maternal hypotension
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nursing care of category 3
- identify the cause of the specific pattern
- stop pitocin infusion if being administered
- reposition the client several times
- administer oxygen via face mask at 8-10liters/minute
- call to have HCP put in internal monitor
- notify HCP of category assessed
- notify other staff to prepare for c-section
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Fetal position
- relationship of presenting part to maternal pelvis
- LOP-left, occipital, posterior
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fetal attitude
degree of flexion of body parts
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engagement
occurs when the largest diameter of the presenting part (BPD) reaches or passes through the pelvic inlet
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Contractions
- frequency: refers to the time between the beginning of one contraction and the beginning of the next one
- duration: measured from the beginning of the increment to the end of the dcrement (45-90 seconds)
- intensity: refers to the strength of the contractions during the acneme or peak
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stages or labor-1st stage
- begins when true labor start through complete cervical dilations
- latent stage-mild contractions 0-3 cm
- active phase-progressive fetal descent 4-7cm
- transition-increase fetal descent 8-10 cm significant anxiety, restless, irritabl, contractons are 1 to 2 minutes apart, strong intensity and lasting 60-90 seconds
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2nd stage
- begins when cervix is 10 cm and ends with birth of infant, pushing stage
- crowning occurs
- usually 1 hour long or less
- laboring down-10cm let the woman's body do the work before we tell them to push. pushing time is decreased and maternal exhaustion are less likely
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3rd stage
- begins from birth of infant to placental separation, about 5 mins
- signs of placental separation are globular shaped uterus, rise of fundus in abdomen, sudden gush of blood, further lengthening of cord form vagina fetal side of placenta delivers first
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4th stage
- 1-4 hours after delivery when physiological adjustment of the mother's body takes place
- uterus remains contracted and in the midline
- bladder may be hypotonic
- vitals taken q15 minute-bradycardic pulse
- lochia rubra-moderate amount
- emotional state-excited, fatigued, or quiet
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lochia
- lochia rubra-reddish color with a few small clots occur for up to three days
- lochia serosa-thinner, brownish pink for 4-10 days
- lochia alba-yellowish which discharge for 10 to 21 days
- lochia should be gone by 6 week check up
- lochia usually has a fleshy smell
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Episiotomy
- turn client to either side to examine area with adequate lighting, separate buttocks
- inspect REEDA-redness, edema, ecchymosis, discharge, and approx of skin edges
- severe intractable episiotomy pain-hematoma
- check status of hemorrhoids
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cardiovascular adaptations of newborn
- at birth fetal circulation must switch to newborn circulation with elimination of 3 fetal structures
- foramen ovale: closes with clamping of cord which increase pressures in left side of heart
- ductus arteriosis (shunting blood from the lungs): closes with an increase in oxygen levels
- duvtus venosus (shunted blood away from liver) cloes within days after placenta is absent
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respiratory adaptations
- hypercapnia, hypoxia and acidosis stimulated the newborns first breath
- adequate surfacant levels prevent alveolar collapse at the end of expiration and promotes gas exchange
- fluid fills lungs now and become air filled and pressure in the left side of the lungs become greater than the right side
- thoracic sqeeze gets rid of lungs fluids
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hepatic system
- stores iron for about 4-6 months
- bilirubin conjugation to prevent overload
- RBC breakdown occurs every 80 days
- enters the GI tract and kidneys to be excreted
- bilirubin overload-jaundice in newborn
- bilirubin is toxic to brain and must be removed or bilirubin encephalopathy develops
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GI
- vitamin K production is dependent on bacterial colonization via milk intake
- stomach capacity is small and CNS control is immature, so regurgitation is frequent
- 5-10% loss of their birth weight within the 1st week due to inadequate digestion and absorption of nutrients
- meconium passed within the 1st 24 hours
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renal system
- inability to concentrate urine until 3 months
- urine has a low specific gravity
- voids frequently 6-12 times daily
- limited ability to excrete salt, water loads, and drugs
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general newborn appearance
- head is disproportional large for body
- head constitutes 1/4 of body size
- body appears long and exremities short
- flexed extremities that resist extension
- hands are tightly clenched
- no neck appearance
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weight and measurements
- average weight is 7.5lbs
- 75% of body weight is water
- 5-10% weight loss in first 3 days of life
average length is 20 inches-will grow 1 inch/month for next 6 months
- head circumference is 13-14 inches
- head is 2cm<chest circumference
- chest circumference is 12-13cm
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vital signs
- temp is 97.5-98.6 axillary
- heart rate is 110-160bpm; regular rhythm
- respirations 30-60bpm: irregular, shallow, unlabored
- symmetrical chest movements
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