Bio ch 12 DNA
What happened in Griffith’s bacterial transformation experiment
HARMLESS BACTERIA CHANGED INTO HARMFUL BACTERIA
What happened when Griffith injected mice with the harmless, R-strain bacteria alone?
The mouse lived
What did Griffith observe when he injected a mixture of heat-killed, disease causing bacteria and live
harmless bacteria into mice?
THE MICE DEVELOPED PNEUMONIA.
What did Avery conclude caused transformation?
DNA IS THE TRANSFORMING FACTOR.
Why did Avery’s experiment work?
BACTERIOPHAGE VIRUSES AND BACTERIA BOTH HAVE DNA
(DNA is a common component in each of them.)
What do bacteriophages infect?
Given the structure of a bacteriophage (See p. 340), where is the DNA?
INSIDE THE HEAD OF THE VIRUS
What is inside of a bacteriophage?
Why did Hershey and Chase label the viral DNA with radioactive phosphorus and not radioactive
DNA CONTAINS PHOSPHORUS BUT NOT SULFUR
What would Hershey and Chase have concluded if both radioactive 32P and 35S were found in the
bacteria in their experiment?
BOTH PROTEIN AND DNA WERE INJECTED INTO THE BACTERIA
Which scientist made X-ray diffraction photos of DNA?
What is Rosalind Franklin’s contribution to the effort to identify the structure of DNA?
X RAY DIFFRACTION PHOTOS OF THE DNA MOLECULE
How is DNA like a book?
DNA HAS STORED INFORMATION THAT CAN BE COPIED AND PASSED ON.
What are the parts of a nucleotide?
EXAMPLE = DEOXYRIBOSE + PHOSPHATE GROUP + CYTOSINE
In eukaryotes where is the DNA?
Which term encompasses/includes all of the rest
(DNA Molecules, histones, chromosomes, nucleosomes)?
How do the percentages of bases compare?
Adenine molecule percentage is about equal to Thymine molecule percentage.
Cytosine molecule percentage is about equal to Guanine molecule percentage.
Why can’t adenine pair with guanine?
THE BASES ARE BOTH LONG.
What does DNA replication achieve?
2 DNA MOLECULES EACH WITH ONE NEW STRAND AND ONE ORIGINAL STRAND
Which enzyme adds base pairs to the strand during DNA replication (See p. 351)?
In prokaryotes=bacteria what binds to the chromosome to start DNA replication?
Given a template structure CTAGGT which new strand would be produced during DNA Replication?
In which cells is the accurate transmission of information most important?
SEX CELLS = GAMETES
What happens when a piece of DNA is missing?
GENETIC INFORMATION IS LOST
Bio ch 12 DNA