Why did the use of LSD decline after its initial popularity?
fear of "bad trips"
cost
Put the following drugs in order from highest to lowest relative hallucinogenic activity: DMT, DET, 5-MeODMT , Psilocin
5-MeODMT
Psilocin
DMT
DET
List three perceptual changes associated with LSD use.
The predominant acute adverse reaction to the hallucinogens is____________________.
panic
List two other physiological effects of the hallucinogens.
vivid visual hallucinogens
distortions of images and movement
Sympathomimetic effects of LSD are enduced within_____________minutes
30
CNS effects are enduced within______________minutes
45
How soon does tolerance to LSD develop?
2-3 days
T/F
There is no clinical withdrawal syndrome associated with LSD use.
True
Who “discovered” LSD, and in what year?
1943 Hoffman
In what year was LSD synthesized?
1938
What was one of the first uses of LSD?
study of mental illness
What is the average effective oral dose of LSD?
0.025mg or 25 micrograms
Name four forms in which LSD is sold.
How is LSD synthesized?
Certain species of rye and other grains produce the ergot fungus. An alkaline hydrolysis of the ergot fungus produces lysergic acid, which is the immediate precursor to LSD.
T/F
The chemical structures of LSD and lysergic acid contain an indole nucleus.
True
Which color test is used to screen for the presence of LSD and other hallucinogens?
p-DM
LSD will fluoresce under________________light.
UV
What is the best method for identifying LSD and the other hallucinogens?
GC/MS
Name the four stereoisomers of LSD.
Which isomer is the only one to have a high degree of physiological activity?
d isomer
What schedule is LSD?
Scedule I
T/F
All isomers of LSD are controlled.
True
What is the molecular ion of LSD?
323
What schedule is lysergic acid amide?
Schedule III
Where can lysergic acid amide be found?
in morning glory seeds and Hawaiian Wood Rose seeds
Where and under what conditions do hallucinogenic mushrooms grow?
humid conditions on cow crap
List two physical properties of hallucinogenic mushrooms.
the way it looks
T/F
Bufotenine is a regioisomer of psilocin.
True
How does ibogaine effect the body?
help individuals remain motionless for long periods while remaining metally alert
How are tryptamines usually abused?
by smoking
What is the nickname given to the effects of the tryptamines?Why?