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(2) blood products that are heat treated (and therefore have no risk of HIV and hepatitis)
albumin and serum globulins
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blood to use in low-birthweight infants, bone marrow transplant patients, and other transplant patients
CMV negative blood
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amount of 2,3 DPG in stored blood is _____ than fresh blood
LOWER (causes left shift/inc O2 affinity)
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hemolysis reaction characterized by back pain, chills, tachycardia, fever, hemoglobinuria
acute hemolysis
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causes of acute hemolysis (2)
ABO incompatibility, antibody mediated
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hemolysis reaction which is antibody mediated against minor antigens
delayed hemolysis
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most common transfusion reaction, due to recipient antibody reaction against WBCs in donor blood
febrile nonhemolytic transfusion reaction
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reaction due to IgG against IgA in an IgA deficient recipient. causes bronchospasm, hypotension, urticaria
anaphylaxis
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usual reaction against plasma proteins or IgA
urticaria
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reaction caused by antibodies to recipient's WBCs, causing clots in pulmonary capillaries
TRALI (transfusion related acute lung injury)
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risk of infusion of >10 units of PRBCs
dilutional thrombocytopenia
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electrolyte imbalance common after massive transfusion
hypocalcemia
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risk of repeated platelet transfusions
anti platelet antibodies
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most common bacterial contaminate of blood products
GNRs (often E. coli)
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most commonly contaminated product
platelets (not refrigerated)
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