The endocrine system coordinates body activities and maintains homeostasis through _________.
chemical messengers
Some drugs that bind to steroid hormone receptors are called agonists. They must be _______.
hydrophobic
True or false? Water-soluble hormones pass through the plasma membrane on their own
False
Red bone marrow cells respond to a hormone called erythropoietin. Why doesn�t a liver or kidney cell respond to this hormone?
Only target cells, which contain the receptors for a hormone, can respond to that hormone (Kidney and liver cells do not contain the protein receptor that binds erythropoietin)
The adenohypophysis is AKA the ______________
anterior lobe of the pituitary gland
the neurohypophysis is AKA the ______________
Posterior lobe of the pituitary gland
ADH & oxytocin are produced by the _________ lobe of the pituitary gland
posterior (neurohypophysis)
FSH, LH, Growth hormone, TSH, ACTH, and Prolactin are produced by the _________
anterior adenohypophysis
True or false? The hypothalamus is often called the �master endocrine gland� since it secretes hormones that control other endocrine glands
True
Over-secretion of which hormone will result in acromegaly?
growth hormone
Growth hormone stimulates growth, especially in muscles and bones. What specific structure in bones contains many target cells for this hormone?
epiphyseal plate (the growth plate in children�s long bones)
(Kennedy) autoimmune disorder in which the cells of the adrenal cortex are perceived as foreign. inadequate secretion of ACTH, bronzing of the skin, weight loss, etc
Addinson's disease
Results in redistribution of body fat and accumulation of fluid in the face, fatigue, high blood pressure, and elevated glucose levels.oversecretion of glucocorticoids or a tumor on either the adrenal cortex or anterior pituitary .
Cushing's syndrome
The adrenal medulla secretes hormones used by the ____ nervous system.
sympathetic
Too little thyroid hormone secretion causes ...
Decreased body temperature and heart rate (decreases metabolic activity of body cells)
Parathyroid hormone stimulates osteoclasts. This would ____ calcium levels in the blood.
increase
Which endocrine gland might be involved in Seasonal Affective Disorder, which occurs in some people during winter, when the days are shorter?
Pineal (melatonin secretion for sleepiness & depression)
Which pancreatic hormone functions to increase blood glucose levels?
glucagon
Glucagon stimulates the liver to break glycogen down into _________, which is then released into the bloodstream
glucose
A person�s own immune system attacks the cells of the pancreas responsible for insulin production
diabetes type I
Characterized by a decreased sensitivity to insulin (insulin resistance)
diabetes type II
the plasma membrane of muscles is the _______________
sarcolemma
_________ is the site where a motor neuron stimulates a muscle
motor end plate
voluntarily controlled muscles:
skeletal
Muscle groups that work together are called __________.
synergistic
area from one Z line to the next is the _____________
sarcomere
The structural and contractile unit of a skeletal muscle is a __________.
sarcomere
Calcium is stored in specialized _______ called a ________.
smooth ER; sarcoplasmic reticulum
The two types of myofilaments in sarcomeres are __________.
myosin & actin
Sarcomeres shorten when ______ binds to _______.
myosin; actin
after death: within 3-4 hours, muscles become ____; after 2-3 days become _________
stiff; relaxed
At a neuromuscular junction, the motor neuron stimulates a muscle fiber by releasing ______, which binds to receptors
acetylcholine
When acetylcholine binds to protein receptors on the muscle fiber�s plasma membrane, _______ is released from the sarcoplasmic reticulum.
calcium
Muscle fibers shorten when the tension produced is just greater than the load: _____
isotonic
Muscles can�t shorten because the load is too great:______
isometric
which muscle fiber type is most powerful?
fast-twitch
The molecule that provides energy for muscle contraction is ____________.
ATP
_______________ uses oxygen and glucose.
aerobic respiration
Wendy the whippet and other "jacked-up" mammals are due to decreased ____________ levels
myostation
_________ connects bone to muscle
tendon
True or false? Anemia of any type causes a lack of oxygen in the tissues, stressing and eventually killing cells
true
a cancer of WBC, causing # of wbc to decrease
leukemia
An increase in ______ indicates the presence of parasites
Eosinophils -- white blood cells that attack parasitic worms
Leukocytes function in ____, while platelets(thrombocytes), _____.
immunity; clot blood
Oxygen is primarily transported by ____.
RBC
What is the metal responsible for oxygen-binding in the hemoglobin molecule?
iron
True or false? The reason that erythrocytes don�t live very long is that cells without DNA are unable to produce and repair old, worn out cell parts
true
Carbon dioxide is primarily transported by ________.
being disolved in the plasma
What cell gives rise to all other blood cells?
stem cells
A bone marrow transplant replaces diseased bone marrow with that from a donor. What complications might you expect from this procedure?
donor tissue may create WBC to attack host(foreign) tissue
What stimulates the production of red blood cells?
erythropoietin
universal donor:__, universal recipient:____
O; AB
Type A red blood cells contain ___ antigens and those individuals make anti-___ antibodies
A; B
Blood type ___ contains no antigens, while blood type ___ makes no antibodies
O; AB
Rh__ mother and Rh_____ baby = antigens formed for the NEXT fetus
negative; positive
what is the initial stimulus for a blood clot to form?
cut to a vessel
Albumin,Fibrinogen,Keratin,Prothrombin: which is not found in the blood??
keratin
A condition in which parasites block the passage of lymphatic fluid returning to blood
elephantiasis
reduced ability of RBC to carry oxygen (by low hemoglobin or RBC count)
anemia
___________ do NOT have ducts
endocrine glands
glucagon and insulin-- this is an example of antagonistic ______ feedback
negative
tyrosine - kinase receives ________
insulin
the binding messenger for calcium (modulates it)
calmodulin
results when the anterior pituitary gland produces excess growth hormone (GH) after epiphyseal plate closure at puberty
acromegaly (Andre the Giant)
short range prostate chemicals that may have anti-inflamitory potential
prostaglandins
expothalamos and Grave's disease are linked with overactive ________
thyroid
_________: regulates calcium
parathyroid
the bone-to-bone connector
ligament
a single motor neuron and its innervated muscle connection
motor unit
___________ filaments contain the myosin heads; ______ filaments hold the actin binding sites
thick; thin
the NT at the end plate is ______________
Acytelcholine
group of muscle diseases that weaken the musculoskeletal system and hamper locomotion
Muscular Dystrophy
The order of muscle energy used, from first to last:
1:
2:
3:
1) Fatty acids
2)glycogen
3) glucose
Sprinters: ______ twitch (type __)
Fast; II
endurance runners: _____ twitch (type __)
slow; I
occurs in skeletal muscles in response to strength training
muscular hypertrophy
______ muscle does NOT have striations
smooth
large, bumpy axon node sites where Action Potentials are created
varicosities
a cardiovascular break in the "plumbing"
aneurism
this can be "smelled" by the other cells; it is involved in immunity recognition (A, B, AB, etc.)
antigen
the test used to determine blood type. Cells clump together when an antibody is present and brings them together
agglutination
"Normal" blood pressure systolic / diasystolic
120 / 80
PATHWAY OF HEART(veins to arteries)
1)_____ atrium leads to 2) ______ ventricle. Then, 3) _____ pulmonary to the lung(CO2 OUT). 4) (O2) comes in the ____ atrium
Right; Left; Left; Left
venous travel is by muscle pumping, valves, and ________
inhaling
bubonic plague was due to inflamed ________
lymphatic nodes
tachycardia is defined as ________ beats per minute
over 100
The medulla oblongata is critical in __________
Heart rate control
_______ Occurs when there is inadequate blood flow to match oxygen usage in the tissues
circulatory shock
________: Due to low blood volume from an injury, dehydration, or burns
hypovolemic shock
Occurs when cardiac output is not sufficient to maintain blood flow required by the body:
congestive heart failure
total peripheral resistance and stroke volume are ______ related
inversely
stroke volume _________ when Contractility or EDV (end-diastolic volume) increases