-
DDx: Bilateral lung opacities in a newborn
"SPERM"
- 1.SDD - granular opac, dec lung vol, not present in full term
- 2.Pneumonia - streaky opac, can have pleural fluid
- 3.Edema - streaky opac, uncommon - TAPVR w/ obstruction
- 4.RFF - streaky, linear opac, can have pleural fluid, should quickly clear
- 5.Meconium aspiration - patchy, heterogenous, inc lung vol, occ.PTX
-
Humeral head ossification centers appear at what age?
36 weeks gestation
-
DDx: Unilateral lucent thorax in a newborn/first week of life
- -a.PTX
- -b.CLE /CLH - usually upperlobe, compressed adj lung
- -c.CPAM - as a large cyst (Type I)
- -d. Bronchial Stenosis-e. Absent pectoralis on one side
-
DDx: Unilateral bubbly thorax in a newborn
- a.CDH - usually left and posterior
- b.CPAM - looks like CDH, but bowel gas normal
- c.PIE - later if on high pressure vent
-
DDx: Unilateral opaque thorax in a newborn
- a.Atalectasis - agenesis, NG towards opac
- b.Pleural effusion - NG away from opac
- c.Congenital mass
- d.CLE (early)
-
DDx: Congenital thoracic malformations
- Parenchymal anomalies (pulmonary sequestration, CPAM)
- Foregut anomalies (bronchogenic cyst)
- Airway anomalies (bronchial atresia, CLE)
-
CPAM types
- Type I - Few big cysts
- Type II - Lots of small cysts
- Type III - Solid
Not prognostically indicative, do not affect management
-
DDx: Diffuse lung opacities in a one week old infant
"PAPE"
- Pneumonia
- Atelectasis
- Pulm Hemorrhage
- Edema (PDA)
-
DDx: Diffuse opacities in a one month old infant
-
UAC placement
inferior to aortic arch and superior to renals
-
UVC placement
junction of ivc and right atrium
-
Diffuse branching lucencies, intubated patient
PIE - pulmonary interstitial emphysema
-
5 entities to be concerned about in a pediatric airway
"BERCH"
subglottic narrowing with soft tissue plaques, emergent airway management - Epiglottitis - thumb shaped epiglottis, aryepiglottic thickening, , emergent airway management
- Retropharyngeal abscess/phlegmon
- Croup - subglottic tracheal narrowing
- Hemangioma - asymmetric tracheal narrowing
-
Aryepiglottic folds on lateral film of neck should be less than?
4mm
-
Stridor worse when quiet, exaggerated tracheal narrowing on expiration
tracheomalacia
-
DDx: Wheezing
- 1. Airways Disease
- Reactive Airways Disease (RAD)
- Viral respiratory infection
- 2. Airway compression
- Mass
- Vascular ring
- 3. Foreign body aspiration
Main role of chest film is to rule out 2 and 3
-
MUST assess on EVERY peds chest film?
Trachea (Airway) and Ribs
-
Two techniques to help in evaluating for foreign body if suspected
- 1. Bilateral decubitus chest radiographs
- 2. Fluoroscopy - same concept
Assess for persistent hyperinflation due to air trapping
-
DDx: Round chest mass in a child
RAG BCS Tumor
- round pneumonia - will usually be sick to help diff from real mass
- abscess
- granuloma
- Congenital
- bronchogenic cysts - water density
- CPAM - can have air fluid level
- sequestration
- Neoplasms (exceedingly rare)
-
DDx: Bilateral airspace disease in kids
- 1.Pus (pneumonia)
- High fever
- Atypical/opportunistic
- 2.Water (edema)
- Cardiogenic (cardiomegaly)
- Noncardiogenic - acute glomerulonephritis, smoke inhalation, near-drowning, neurogenic
- Hydrocarbon ingestion
- 3.Blood (hemorrhage)
- Idiopathic pulmonary hemosiderosis (IPH)
- Goodpasture’s, Wegener’s, blood dysrasias
-
DDx: Anterior mediastinal mass in children
- Lymphoma
- Germ cell tumors (benign & malignant)
- Lymphatic malformation (“cystic hygroma”)
- Rare thymic lesions
- -thymic cyst
- -thymoma (adults)
- -thymolipoma
-
DDx: Fluid density anterior mediastinal mass in a child
- Teratoma
- Thymic cyst
- Lymphatic malformation - classic if very extensive into neck or axilla
-
DDx: Middle mediastinal mass in a child
- 1.Foregut duplication cyst
- Bronchogenic cyst - subcarinal
- Esophageal duplication cyst - adj to esophagus
- 2.Adenopathy
- Inflammatory > malignant
-
DDx: Posterior mediastinal mass in a child
- 1.Neurogenic tumor (90%)
- 2.Other
- -a.Hernia
- -b.Adenopathy
- -c.Osteomyelitis/diskitis
- -d.Extramedullary hematopoesis
- -e.Vascular
-
Neurogenic tumors in kids: more aggressive or less aggressive with age???
Less aggressive with age:
- 1.Neuroblastoma (younger child, malignant tumor)
- 2.Ganglioneuroblastoma (in between)
- 3.Ganglioneuroma (older child, benign tumor)
-
DDx: Extrapulmonary thoracic masses in kids
- Malignant
- Mets - Neuroblastoma, leukemia, lymphoma
- Primary - Ewings and Askin tumors; less often osteosarc and rhabdomysarcoma
- BenignSoft tissue tumors - Lymphangioma, lipoma, hemangioma
- Benign bone tumors - EG, fibrous dysplasia, osteochondroma
- Infection (including osteomyelitis)
-
Flattened vertebral bodies, short ribs, curved femurs, lethal dysplasia
Thanatophoric dysplasia
"telephone receiver" femurs
-
–Posterior scalloping of vert. bodies
–Narrowing interpedicular distances
–Tombstone iliac wings
-Frontal bossing
- Achondroplasia
- •Most common short-limbed dwarfism
- •Autosomal dominant
- •Often sporadic
-
–Osteopenia
–Multiple fractures
-Accordian ribs
-Wormian bones
- - Osteogenesis Imperfecta
- DDx:
- -Leukemia
- -Rickets
- -NAT
-
- Micromelia - diffuse shortening of extremities
- Lethal
- Spine poorly mineralized
Achondrogenesis
-
–Normal spine
–Small thorax
–respiratory distress
–Handlebar clavicles
–Trident acetabulum
Asphyxiating Thoracic Dystrophy
-
–Clavicles total or partially absent
–Wormian bones
–Widened pubic symphysis
Cleidocranial Dysplasia
-
–Vertebral body beaking
–Widened ribs
–Madelung deformity
-Thick skull
- Mucopolysaccharidoses
- •Lysosomal storage disorders
- –Hurlers and Hunters Syndrome - Anterior inferior vertebral beaking
- –Morquio Syndrome - Anterior and middle vertebral beaking
-
DDx: Stippled epiphyses
- •Chondrodysplasia punctata
- •Multiple epiphyseal dysplasia
- •Fetal alcohol/ warfarin exposur
-
DDx: of Amniotic Band Syndrome
- •Amniotic band
- •Thermal injury
- •Thromboembolic disease
-
DDx: Hip joint effusion
- •Septic arthritis
- •Toxic synovitis
- •Hemarthrosis –trauma, hemophilia
- •Arthropathy
-
Joint erosions, Soft-tissue swelling, osteopenia, accelerated skeletal maturation
•Ankylosis is late finding
- Juvenile Chronic Arthritis
- DDx: Klippel-Feil
-
Highly specific fractures for non-accidental trauma
- –Metaphyseal corner fractures
- –Posterior rib fractures
- –Scapular fractures
- –Sternal fractures
-
•Idiopathic AVN of femoral head
•Age 4-8 years
Legg-Calve-Perthes Disease
-
DDx: Bilateral femoral head AVN
- - Steroids
- - Sickle Cell
- NOT usually LCP Dz
-
Widened epiphysis of femoral head neck, 25% bilateral, teenagers
- SCFE
- •Emergent finding-orthopedic surgery should be notified
- •Pre-teen to early teenagers
- •More common in obese children
- •Salter I fracture
-
•Metaphyseal Lucent Bands
Think leukemia
-
–Osteopenia/cortical thinning
–Periosteal reaction
–Soft tissue masses
–Pathologic fractures
–Lytic lesion with benign periostitis
EG
-
Increased risk of DDH with:
- females,
- Caucasian,
- breech delivery
-
Tibia vara
•Medial tibial metaphyseal beaking
•Beak is depressed, irregular and fragmented
•Late –medial physeal narrowing, with possibly early medial fusion
Blount's disease
-
DDx: Demineralization and metaphyseal splaying
-
Flat or anteriorly downward pointing calcaneous
Equinus calcaneous
Hind and forefoot varus with EC = clubfoot
-
•Premature Infants brain pathology
- –Intracranial hemorrhage - caudothalamic groove
- –Periventricular leukomalacia
- –Intracerebellerhemorrhage
-
•Term Infants
- –Hemorrhage•Extra-axial
- –Subarachnoid
- –Subdural (birth trauma)
- •Parenchymal Hemorrhage
- –Choroid, thalamus, subpial region
- –Hypoxic-Ischemic Encephalopathy
-
Germinal matrix grading system
- 1. Subependymal hemorrhage
- 2. Hemorrhage plus blood in non-dilated ventricles
- 3. Hemorrhage plus blood in dilated ventricles
- 4. Intraparenchymal, subependymal and intraventricular hemorrhage
-
Periventricular Leukomalacia stages
- •Early –often normal
- •Two weeks -echogenicity of periventricular white matter
- •Three weeks –cystic encephalomalacia
- •Late –cerebral atrophy, ventricular enlargement
DDx –Periventricular blush - normal finding - Ill-defined borders - Echogenicity < Choroid
-
–Increased echogenicity
–Loss of gyral-sulcal interfaces
–Slit-like ventricles
Hypoxic-ischemic encephalopathy
- DDx:
- –cerebritis, edema, hemorrhage
-
Cystic focus adjacent to lateral ventricle, but more anterior than PVL
Coarctation of the lateral ventricle
Normal finding
-
•CSF collection in abnormal split in leptomeninges
•No communication with CSF or ventricles
Arachnoid cyst
-
Cystic structure in the midline of the brain in an infant should always be evaluated with?
Color flow doppler
-
•Fistulous connection between cerebral arteries and midline prosencephalic vein
Vein of Galen malformation
-
•Complete or partial absence of the interhemispheric commissural fibers
•US findings
–Partial/complete absence of corpus callosum
–Widely separated, parallel lateral ventricles
–Ventriculomegaly(colpocephaly)
–Radiallyarranges gyri/sulc
Dysgenesis of the corpus callosum
-
•Failure of midline cleavage of the brain
holoprosencephaly
-
Lack of septum pallucidum on ultrasound
Septo-optic Dysplasia
-
DDx: Focus of hypoechogenicity in the spinal cord in a newborn on US
- -Ventriculus Terminalis - normal, stable
- –Syrinx
- –Transient dilation of central canal - normal, disappears in first few weeks of life
-
DDx: Renal masses in children
- Wilms’ tumor - 87% of renal masses in kids, 5-10% b/l
- Rhabdoid tumor
- Clear cell sarcoma
- Renal cell carcinoma
- Congenital mesoblastic nephroma - under 6 mos most likely, benign solid tumor
- Pyelonephritis/lobar nephronia
- Multilocular cystic nephroma
- Misc: angiomyolipoma, mesenchymal masses, metastases, lymphoma
-
Most likely mets from Wilms
Lung then liver
-
Which peds renal tumor likes to invade the IVC and create thrombus?
Wilms'
-
If B/L Wilms' tumors think of what?
nephroblastomatosis and familial causes
-
DDx: Multifocal Renal Masses in kids
- Nephroblastomatosis - follow closely - (Wilms' risk)
- Pyelonephritis
- Lymphoma/Leukemia
- Metastases
- Infarcts (assoc. with sickle cell disease)
-
How to know if a nephroblastoma has converted to Wilms?
Has begun to enhance or has grown out of proportion to remaining lesions
-
Well-circumscribed lesion containing variable sized cysts surrounded by fibrous capsule
Multilocular Cystic Nephroma
- Bimodal age and sex distribution
- –Boys < 4
- –Girls 4-20
- -women > 40
-
DDx: Adrenal masses
- Neuroblastoma - 10% of pediatric malignant tumors, lift aorta off spine char.
- Adrenal hemorrhage - MC neonatal mass, should resolve with time, can be solid
- Teratoma
- Adrenal carcinoma
- Pheochromocytoma
-
Irregular extra-renal mass, lifts bladder and aorta
Density less than adjacent tissues
No definable capsule
Midline extension, encases vessels
Calcifications 85%
Neuroblastoma
-
Most common mets from Neuroblastoma
Liver, Bone
-
Best nucs test for neuroblastoma mets
MIBG
-
DDx: Pediatric Hepatic Masses
- Hepatoblastoma -90% elevated AFP, <5 yrs
- Hepatocellular carcinoma - 50/50 elevated AFP, >5 yrs of age
- Hemangioendothelioma - infants, heart failure, diffusely infiltrative
- Mesenchymal hamartoma - never AFP, 4mos-2yrs, cystic
-
DDx: Pediatric Pelvic Masses
- Ovarian cysts
- Hematocolpos
- Ovarian tumors
- Neuroblastoma
- Rhabdomyosarcoma
- Sacrococcygeal Teratoma
- Lymphoma
-
DDx: Cystic Abdominal Masses
- Abscess
- Pseudocyst
- Duplication cyst
- Urachal/Meckel’s/Omphalomesenteric
- Lymphatic malformation - can look like an abscess
- Blood
- (consider bladder, ovarian cyst in pelvis)
-
Most abdominal masses in children are what in origin?
Renal - 50%
-
Heterogenous enlarged kidney in a pediatric patient
- Think pyelonephritis, abscess can be seen on U/S as well
- Look for cortical scarring on DMSA
-
-
Most common cause of UPJ in childhood
- UPJ obstruction - associated with other urinary abnormalities
- Must differentiate from MCDK
-
Most common cause of urethral obstruction in boys
- posterior urethral valve
- US: thick bladder wall with bilateral pelvocaliectasis, +/-urine ascites
- VCUG: dilated posterior urethra, trabeculated bladder, reflux in 50%
-
DDx: Unilateral renal enlargement in pediatric patient
- Hydronephrosis
- Pyelonephritis
- Renal vein thrombosis - echogenic heterogenously enlarged kidney
- Wilms’ or other tumor
- Renal duplication
- Compensatory hypertrophy
- Multicystic dysplastic kidney
-
DDx: Bilateral renal enlargement
- “Medical renal disease”
- –Nephroticsyndrome
- –Acute glomerulonephritis
- –Acute hypoxic ischemic injury
- –Hemolytic-uremic Syndrome
- ARPCKD
- ADPCKD
- Nephroblastomatosis
- Bilateral Wilms’ tumor
- Leukemia/lymphoma
- Bilateral hydronephrosis
- Bilateral pyelonephritis
- Bilateral renal vein thrombosis
- Bilateral duplication
- Beckwith-Weidemannsyndrome
-
DDx: Renal cystic disease
- Solitary simple renal cyst
- Calycealdiverticulum
- Multicysticdysplastic kidney
- ARPCKD
- ADPCKD
- Medullary cystic disease
- -Juvenile nephronopthisis
- -MedullarySponge Kidney
- Syndromes
- -Tuberous sclerosis
- -von Hippel-Lindau
- -Zellweger
- Cystic neoplasms
- -Multilocularcystic nephroma
- -Other tumors (necrotic)
-
Small dysmorphic kidney in the pelvis
Renal ectopia, can be cross-fused
-
Weigert Meyer Rule
- Upper Pole - Obstructs - Connect Inferior and Medial (UIM)
- Lower Pole - Refluxes (drooping lily on VCUG) - Connects Superior and Lateral (LSL)
-
Most common renal anomaly
Horseshoe kidney
-
Increased risk of what masses with horseshoe kidney
-
DDx: Bladder Masses in kids
- Hematoma
- Rhabdomyosarcoma - most common ST sarcoma in children
- Ureterocele
- Cystitis with asymmetric/focal bladder wall
- Fibroepithelialpolyp (of posterior urethra)
- Foreign body/Bladder stone
-
DDx: Early filling defect on VCUG
- Prolapsing ureterocele
- Diverticulum
- Bladder Mass (polyp or neoplasm)
- Hemmorhage
-
Drooping lily sign
- Lower pole reflux in a duplicated collecting system
![Image Upload 4](/flashcards/images/image_placeholder.png)
-
1.absent abdominal wall musculature
2.cryptorchidism
3.GU anomalies
- Prune-Belly or "Eagle-Barrett" Syndrome
- 99% male
- Imaging:
- •tortuous dilated ureters
- •vesicoureteral reflux
- •dilated prostatic urethra
-
Dilated proximal esophagus, NG won't pass, but there's bowel gas noted; baby can't handle secretions
Think tracheoesophageal fistula
- Associated findings on prenatal ultrasound
- –Polyhydramnios after 20 weeks
- –Intrauterine growth restriction (IUGR)
- –Nonvisualized or small fetal stomach
-
Proximal esophageal pouch no bowel gass
Esophageal atresia without fistula
-
Shaggy air pouch around trachea
- Perforation Pseudodiverticulum
- Traumatic perforation usually due to ET tube
-
DDx: recurrent pneumonia in pediatric patient
- - H or N type tracheoesophageal fistula
- –GE reflux and aspiration
- –Aspirated foreign body
- –Immunodeficiency
- –Cystic fibrosis
- –Infected congenital pulmonary anomaly
-
VACTERL associations
- V Vertebral Segmentation Anomalies
- A Atresia of Anus or Duodenum
- C Cardiac : VSD, PDA, TOF
- T Tracheal-Esophageal Fistula
- E Esophageal atresia
- R Renal Anomalies
- L Limb anomalies (radial ray)
-
TEF repair complications
- Poor esophageal motility
- Anastomoticstricture
- Esophageal leak
- GE reflux
- Recurrent fistula
- Tracheomalacia
-
"caterpillar stomach sign"
- Hypertrophic pyloric stenosis
- - US Thickness of wall > 3mm]
- - US Channel length > 14mm
![Image Upload 6](/flashcards/images/image_placeholder.png)
-
DDx: Double bubble sign
"D-MADS"
- •Duodenal atresia
- •Malro with Midgut Volvulus
- •Annular Pancreas
- •Duodenal Web
- •Severe duodenal stenosis
![Image Upload 8](/flashcards/images/image_placeholder.png)
-
Location of defect / umbilical cord with gastroschisis and omphalocele
- gastroschisis - defect to right of midline umbilical cord
- omphalocele - cord inserts at apex of protruding bowel/mass
-
Acquired duodenal obstructions
"IRIS"
- Intramural Hematoma
- Radiation Injury
- Intussusception
- Superior Mesenteric Artery Syndrome
-
DDx: Prenatal cystic abdominal mass
"HCC MODEL"
- Hydronephrosis
- Choledochal cyst
- Cystic teratoma
- Meconium pseudocyst
- Ovarian cyst
- Enteric duplication cyst
- gut signature, can bleed or cause intuss. - Duodenal atresiaLymphatic malformation
-
DDx: Biliary emesis
- Malrotation with midgut volvulus
- Jejunal or ileal atresia
- Meconium ileus
- Other distal obstruction
-
Congenital Distal Bowel Obstruction
"IF HAM"
Microcolon, small caliber distal ileum - Functional Immaturity of the Colon–
Meconium plugs, (+/_ small left colon, abrupt transition at splenic flexure), distendable rectum - Hirschsprungs–
Narrow rectum, cone shaped transition, normal rectosigmoid index should be >1- Anorectal Malformation - usually some sacral deformity, poss. presacral mass, VACTERL assoc.
- Meconium Ileus–
Microcolon, meconium obstructs terminal ileum
-
DDx: calcifications in the neonatal/pediatric abdomen/pelvis
"MAIN G"
- -Meconium peritonitis
- -Adrenal hemorrhage
- -Infectious sequelae
- -Neoplasm
- -Gallstone
-
DDx: Bubbly lucencies in the abdomen of a newborn
- Normal stool with normal bowel gas pattern
- Meconium ileus
- –Bubbles in right abdomen (air mixed with meconium in the terminal ileum) with proximal bowel obstruction
- Necrotizing enterocolits
- –Bubbles of air below the bowel mucosa
- –/+ crescentic air between the bowel serosa and bowel wall muscle
- –/+ Portal venous gas
- –/+ Free air from perforation
-
DDx: Microcolon, unused fetal colon
- •Meconium Ileus
- •Jejunal < Ileal Atresia
- •Total Colonic Hirschsprungs (uncommon)
-
DDx: Multiple lucent skull lesions
- •Eosinophilic granuloma
- –< age 5years multiple
- •Lymphoma
- •Metastatic disease
- –Neuroblastoma
-
•Multiple lytic lesions skull with a beveled edge–Outer table > inner table; Vertebra plana C6; floating teeth
Eosinophilic granuloma/ LCH
-
Anterior urethral obstruction
- •Stricture
- –Congenital
- –Acquired
- •Anterior Urethra Valves
- •Anterior Urethral Diverticulum
-
Classic target lesions on T2 MR imaging
Plexiform neurofibroma of NF1
-
Generalized osteosclerosis in kids
- •Osteopetrosis
- •Physiologic sclerosis of the newborn (normal)
- •Hypervitaminosis A or D
- •Renal osteodystrophy / hypercalcemia
- •Healing rickets
- •Pycnodysostosis (micrognathic)
- •Hypothyroid
- •Osteopathia striata
-
multiple enchondromas in the bones
Ollier's disease
-
multiple enchondromas + venous malformation with poss.phleboliths
Maffucci's sydrome
-
DDx: Permeative process of the bone in a kid
"OLEO"
- •Osteomyelitis
- •Lymphoma
- •Ewing's sarcoma
- •Osteosarcoma
-
fluid fluid levels on MR in a distal femur mass with soft tissue involvement
- teleangiectatic osteosarcoma
- -common lung mets
- -can calcify
-
Findings of Classic Dandy Walker Malformation
"CReATE"
- •Complete or partial vermian agenesis
- •Retrocerebellar cyst communicating with the fourth ventricle
- •Absence of the falx cerebelli
- •Torcular elevation above the lambda
- •Enlarged posterior fossa
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