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Drug transfer across the placenta is affected by which of the following?
a. Concentration difference
b. Lipid solubility of the drug
c. Degree of ionization
d. Diffusion Coefficient
e. Molecular drug weight
A, B, C and E
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Teratogenic drugs generally have their greatest effect during:
The first trimester
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A lipid-soluble drug has which of the following characteristics?
a. Readily cross cell membranes
b. Concentration is higher in tissues than in plasma
c. High affinity for protein binding
d. 10% is bound to albumin
e. Distributed slowly to the heart and kidneys
A and C
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Of the following, which is not a type of biochemical reaction of drug metabolism in the liver?
Excretion (p. 226)
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Of the following antibiotics, which is considered to be bacteriostatic?
Tetracycline (p. 231)
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Name a Penicillin
Ampicillin
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Name a cephalosporins
Cephalexin
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Name a Aminoglycosides
Gentamicin
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Name a Macrolide
Erythromycin
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Name a Quinolone
Enoxacin
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Name a Tetracycline
Doxycycline
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Name a sulfonamide
Sulfadiazine
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Name a Antifungal
nystain
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Name an antiviral
Ribavirin
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Which drug would be most appropriate to treat congestive heart failure?
Digoxin
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Which drug would be most appropriate to treat supraventricular tachycardia?
Adenosine
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Which drug would be most appropriate to treat severe hypotension?
Dopamine
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Acute bronchospasm would best be treated with which of the following drugs?
Albuterol
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Neonatal apnea is treated with which of the following?
Caffeine
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Which of the following best describes the effects of glucocorticoids?
a. Combat infections
b. Stabilize cell membranes
c. Inhibit macrophage accumulation
d. Increase the release of adrenocorticotropic hormone
e. Promote Gluconeogenesis
B, C, and E
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The drug that inhibits mast cell degranulation is:
Cromolyn sodium
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Which of the following would be the drug of choice in sedating a neonate following surgery?
Chloral hydrate (p. 252)
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Restlessness, irritability, tremors, high-pitched cry, and vomiting are all signs of:
Fetal Drug withdraw
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