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Asexual reproduction:
- Duplication of self (does not require 2 gametes)
- Replicating DNA
- Mitosis is this type of cell division
- Advantages: Takes less energy
- Disadvantage: No variabity=No adaptation (bad for natural selection)
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Sexual Reproduction:
- Gametes (haploid,n) come together during fertilization to produce offspring
- MEIOSIS
- Advantages: increased variation
- Disadvantages: requires more energy
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Chromatin:
40% DNA and 60% protein
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Euchromatin:
Only condensed during cell division. At other times it is uncoiled (found at the expressed portions of DNA)
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Heterochromatin:
Always condensed (portion of the DNA in not expressed)
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Chromatid:
One of two identical strands of a chromosome
Sister chromatids: two identical copies of a chromatid connected by a centromere.
When two strands seperate they are called DAUGHTER CHROMOSOMES.
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Chromosome:
A single piece coiled DNA, mad of chromatin
Homologous chromosomes: Two different copies of the same chromosome (can be single or double stranded)
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More chromatids and chromosomes:
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Mitosis vs meosis:
- Mitosis: results in the seperatin of replicated chromosomes into two identical daughter nuclei
- -somatic cell: body cells, two sets of chromosomes (diploid,2n)
- Meiosis: results in daughter cells with 1/2 chromosomes of the parent cell
- -gamete: sex cells, one set of chromosomes (haploid,1n)
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Interphase:
the period between mitotic and meiotic division in which there is cell growth and DNA replication.
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Cytokinesis:
Division of one cell into two cells
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Mitossis *interphase:
- (longest phase)
- G1: gap1 synthesis of mRNA for use in protein synthesis (takes 6-12)
- S: synthesis, DNA is synthezied (replicated), going from one chromatid to sister chromatid (6hours)
- G2: gap 2, synthesis of molecules and structures needed for mitosis (5hours)
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Mitosis: interphase checkpoints:
- Control mechanisms that ensure cell division is proceeding acurately.
- G1/S: check for enough proteins, general health of cell, and DNA damage.
- G2/M: looks at DNA damage that occured during replication.
- -Apoptosis (cell suicide)
- -Go back to interphase and correct process
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Mitosis: Prophase
- Condensing of the chromosomes (easier to move)
- Nuclear membrane begins to breakdown
- Nucleoli disappear
- Beging to form spindles (Actin fibers)
- Maturation of kinetochores (proteinaceous material on the sides of the centromere)
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Mitosis: metaphase
- Kinetochores attach the chromosomes to the spindles
- chromosomes align along the mitotic plate
- There is also a spindle checkpoint
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Mitosis: Anaphase
- Seperatin of chromosomes
- Sister chromatids begin to move towards the poles via spindles (forming identical cells)
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Mitosis: Telophase
- Cytokinesis occurs (cell plate formation in plants and cleavage furrow in animals
- Spindles dissasemble
- Kinetochores disappear
- Nuclear membrane reforms
- Nucleoli reappear
- Chromosomes become uncondensed
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Mitosis in short:
- Interphase: prepare
- Prophase: condense
- Metaphase: line up
- Anaphase: split
- Telophase/Cytokinesis: two new dipliods
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Onion/Garlic root tip slides:
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Meiosis I:
- •Pre-meiotic Interphase:
- –prepare cell for division
- –replication of chromosomes
- •Prophase I:
- chromosomes condense
- –Formation of spindles and centrioles
- –Homologous chromosomes pair in synapse forming tetrads
–Crossing over and recombination (chiasmata)
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Meiosis I continued:
- •Metaphase I:
- –Tetrads line up
- –Chromosome position is random (independent assortment of chromosomes)
- •Anaphase I:
- –Homologous chromosomes separate
- •Telophase I:
- –One chromosome of each pair arrives at pole
- –Cytokinesis occurs
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Meiosis II:
- •Interkinesis (Interphase II):
- –Cell prepares for division
- –NO DNA replication
- •ProphaseII:
- –Chromosomes reappear
- –Spindles form
- –Nuclear membrane breaks down
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Meiosis II continued:
- •MetaphaseII:
- –Chromosomes line up
- •AnaphaseII:
- –Sister Chromatids separate
- •TelophaseII:
- –Chromatids arrive at poles
- –Cytokenesis occurs
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Spermatogenesis:
- Males:
- •Maintain many cells (spermatogonia) that
- are diploid and can constantly undergo mitosis
- •Two daughter cells (primary
- spermatocytes) go through meiosis to produce four haploid cells (spermatids)
•Spermatids mature into sperm
•Process takes 9 weeks
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