Path MT I

Autonomous hypersecretion due to hyperactivity (primary hyperfunction) of an endocrine gland can be due to what two things?

Secondary hyperfunction in an endocrine gland is usually due to what?

Excess secretion of peptides similar to hormones causing hyperactivity can be caused by what?

What are some examples of iatrogenic syndromes of hormone excess?

What are three possibilities responsible for primary hypofunction of an endocrine gland?

What can be due to secondary hypofunction of an endocrine gland?

What are two explanations for endocrine dysfunction due to failure of target-cell response?

In what breeds of dogs is it common to find pituitary cysts and pituitary dwarfism?

What is pituitary cysts and pituitary dwarfism due to?

What lesions are associated with pituitary cysts and dwarfism?

What clinical signs are associated with pituitary cysts and dwarfism?

If a tumor is producing trophic hormones that stimulate target organs, how is it described?

If a tumor is destructive to adjacent structures causing hypoactivity of an endocrine gland, how is it described?

What are the most common endocrine gland tumors of adults?

What are the most common endocrine tumors of younger animals?

What is the most common pituitary neoplasm in horses?

What is the second most common pituitary neoplasm of the dog?

What functionally active tumor is derived from corticotroph cells in the pars distalis or the pars intermedia of dogs and is common in adult aged boxers, boston terriers and dachshunds?

In what animals is endocrinologically inactive chromophobe adenoma usually seen in?

What clinical signs are associated with endocrinologically inactive chromophobe adenoma?

What benign tumor is derived from the epithelial remnants of Rathke's pouch and causes abnormal secretion of somatotropin (growth hormone)?

What clinical signs are associated with craniopharyngioma (intracranial germ cell tumor)?

What type of inflammation is seen sporadically in ruminants and swine?

What is the etiology behind pituitary abscesses, common in ruminants and swine?

What can a lesion in the neurohypophysis that interferes with ADH synthesis or secretion cause?

What form of diabetes insipidus is a hereditary defect resulting in lack of adenylate cyclase in the plasma membrane of epithelial cells in the distal tubules and collecting ducts?

Hemorrhage of the adrenal cortex can be due to what three things?

What syndrome of the adrenal cortex is usually a fatal consequence of overwhelming sepsis but can also be due gram-positive organisms, anticoagulant therapy and trauma?

In what animals is nodular hyperplasia of the adrenal cortex seen in?

What is the result of nodular hyperplasia of the adrenal cortex?

In what animals are cortical adenomas of the adrenal cortex seen in?

In what hyperplasia/neoplasia of the adrenal cortex do you see multiple small foci, usually bilateral and without encapsulation?

In what hyperplasia/neoplasia of the adrenal cortex do you see larger, unilateral and encapsulated growths?

In what animals are coritcal carcinomas usually seen in?

What type of tumor of the adrenal cortex is larger than adenomas, often bilateral, and may invade the vena cava?

What is the second most common neoplasm reported in adult ferrets?

What clinical signs are associated with functional proliferative lesions in ferrets?

What percent of Cushing's disease is due to primary hyperadrenocorticism?

What percent of the Cushing's disease is due to secondary hyperadrenocorticism?

What percent of Cushing's disease is due to pharmacological (iatrogenic) hyperadrenocorticism?

What possible pathogenetic mechanisms can cause Cushing's disease?

What clinical signs are associated with Cushing's disease (hypercortisolism)?

What are some pathogenetic mechanisms responsible for primary hypoadrenocorticism?

What primary hypoadrenocorticism involves the destruction of all three cortical layers, a deficiency in production of all cortical hormones, and is see most frequently in young to middle-aged female dogs?

What primary hypoadrenocorticism is due to adrenalitis, infarction, hemorrhage and tumors?

What type of primary hypoadrenocorticism involves sudden withdrawal following prolonged excessive administration of synthetic steroids?

What must be done for a dog to usually get Addison's disease (hypoadrenocorticism)?

ACTH deficiency from a destructive pituitary lesion usually only leads to which two zones in the adrenal gland to be destroyed (mineralocorticoids are not affected)?

What clinical signs are usually seen with hypoadrenocorticism?

What is the most common neoplasm of the adrenal medulla in animals?

In which animals i pheochromocytoma usually seen?

What pathogenetic mechanisms can cause goiter (hyperplasia of the thyroid gland)?

What type of goiter do you see in young adult and adult animals following the correction of the problem in diffuse hyperplastic goiter?

What type of goiter do you see in young animals born to dams on iodine deficient diet or excess iodine, fed goitrogenic substances or plants of Brassicacceae family?

What type of goiter is an incidental lesion in old animals (horses, cats, and dogs) and is nonfunctional in most animals except cats?

What type of goiter is the result of an autosomal recessive disorder in some breeds of sheep, Afrikander cattle, and Saanen dwarf goats?