Aminophylline

Xanthine

Xanthine Bronchodilator that sometimes is effective in cases where Sympathomimetics have not been effective.

Relaxes bronchial smooth muscle but does not act on adrenergic receptors. Mild diuretic properties can increase HR & Cardiac output.

• Onset: 15min
• Peak: 15min
• Duration: Varies
• Half-life: 4hrs

Treatment of infants w/ apnea. Bronchial asthma, Reversible bronchospasm associated w/ chronic Bronchitis, Emphysema, CHF and Pulmonary Edema

Known Hypersensitivity, Uncontrolled Cardiac Arrhythmias

Cardiac monitor, Arrhythmia, PVC, Tachycardia, palpitation, chest pain, nervousness, headache, seizure, nausea/vomiting, hypotension from rapid administration.

CHF/fluid overload NOT present 250 or 500mg (2-5mg/kg) in 90 or 80ml of 5% Dextrose infused over 20-30min

CHF Present 250 or 500mg in 20ml of 5% Dextrose

6mg/kg loading dose infused over 20-30min

• Adult: Titrate to Effect
• Pedi: Don't exceed 12mg/kg in 24hrs

IV/IO

Vials