21 Study Guide

T/F
Early initiation of iron-rich cow's milk in an infant's diet is an excellent preventive measure against iron deficiency anemia.
True False

T/F
Although a frequent problem, ABO incompatibility seldom results in significant disease.
True False

T/F
Sequestration crisis is a serious complication of sickle cell disease unique to childhood.
True False

T/F
Rh incompatibility is a problem only of an Rh-positive woman bearing an Rh-negative fetus during a second pregnancy.
True False

T/F
Because homeostasis in the newborn is chiefly attained through the extrinsic pathway, serious bleeding in the newborn period usually is not a problem in hemophiliacs.
True False

T/F
Idiopathic thrombocytopenic purpura is a genetically transmitted disease.
True False

T/F
Leukemias are multifactorial diseases with genetic disposition, environment, and bacterial infections playing a role in their etiologies.
True False

Which is the most common blood disorder of infancy and childhood?
A. iron deficiency anemia
B. folate deficiency anemia
C. pernicious anemia
D. sideroblastic anemia

Maternal-fetal blood incompatibility may exist in which condition?
A. Rh-negative father, Rh-positive mother
B. Rh-negative mother, Rh-positive fetus
C. Rh-negative father, Rh-positive mother
D. Rh-positive mother, Rh-negative fetus

Beta-thalassemia is:
A. common among Italians.
B. an X-linked recessive disorder.
C. an autosomal recessive disorder.
D. Both a and b are correct.
E. Both a and c are correct.

Which statement is correct?
A. Sickle cell disease is an X-linked recessive disorder.
B. Sickle cell disease is an autosomal recessive disorder.
C. Sickle cell disease is an X-linked dominant disorder.
D. Sickle cell disease is an autosomal dominant disorder.

Idiopathic thrombocytopenic purpura involves antibodies against:
A. neutrophils.
B. platelets.
C. basophils.
D. eosinophils.

Which are factors associated with iron deficiency anemia?
A. rapid growth
B. low socioeconomic status
C. cow's milk for infants
D. Both a and c are correct.
E. a, b, and c are correct.

What is the most likely cause of idiopathic thrombocytopenic purpura?
A. stress and fatigue
B. genetic predisposition
C. prolonged occult bleeding
D. viral sensitization
E. Both b and c are correct.

Hodgkin lymphoma has:
A. extensive extranodal involvement.
B. rare extranodal involvement.
C. painless cervical lymphadenopathy.
D. Both a and c are correct.
E. Both b and c are correct.

In sickle cell disease, vasoocclusive crisis is the result of:
A. "plugging" of microcirculation by "stiff" sickled erythrocytes.
B. ingestion of sulfa drugs.
C. damage to platelets caused by IgG.
D. sequestration of large numbers of erythrocytes in the spleen.

Which factor may play a part in the development of childhood leukemia?
A. genetic predisposition
B. environmental factors
C. viral infections
D. radiation
E. All of the above are correct.

Which statement is true about acute lymphocytic leukemia?
A. It is the most common childhood leukemia.
B. It usually occurs between 2 and 6 years of age.
C. It is uniformly fatal.
D. It is easily predicted through genetic testing.
E. Both a and b are correct.

Leukocyte counts approaching 100,000mm³
A. hemophilia
B. sickle cell disease
C. Rh incompatibility
D. ITP
E. leukemia

Low platelet counts
a. leukemia
b. ITP
c. sickle cell disease
d. Rh incompatibility
e. hemophilia

Lack of coagulation factors VII, IX, and XI
a. leukemia
b. ITP
c. sickle cell disease
d. Rh incompatibility
e. hemophilia

May present early as symmetric, painful swelling of hands and feet
a. leukemia
b. ITP
c. sickle cell disease
d. Rh incompatibility
e. hemophilia

May cause severe hemolysis in the newborn period
a. leukemia
b. ITP
c. sickle cell disease
d. Rh incompatibility
e. hemophilia

May result in aplastic crises
a. leukemia
b. ITP
c. sickle cell disease
d. Rh incompatibility
e. hemophilia

May result in fetal death
a. leukemia
b. ITP
c. sickle cell disease
d. Rh incompatibility
e. hemophilia