-
Observational research design
- study in which individuals are observed or certain outcomes are mesaured
- no attempt (treatment) given to affect the outcome
-
Cohort Research Design
- study thtat compares a particular outcome in groups of individuals who are alike in many ways but differ by a certain characteristic
- ex female nurses whos smoke compared those who dont
-
Case control Research design
- compares two groups of people
- with disease or condition under sdudy(cases) and a very similar group of people who do not have the disease or condition (control)
- study medical,lifestyles
- learn factors
- ex. one given a substance that other was not
-
Epidemiological Research design
- the branch of medical science that deals with the study
- incidence
- distribution
- control of a disease in a population
-
Randomized clinical Trial research
- study in which the participants are assigned by chance to seperate groups that compare idfferent treatments
- rsearchers nor the participants can choose group
- patients choice to be randomized trial
-
Cross Sectional research
- analysis studies the relationship between different variables at a point in time
- relationship between income,locality,and personal expenditure
- related to how variables affect each other at same time and period
-
Longitudinal research design
- correlation research study involves repeated observations of the same items over ling periods of time
- often many decades
- type of observational study
- used in psychology developmental trends
- track same people
- also used in medicine
-
Prospectie Research
- follows over time groups of individuals who are alike in many wasy but differ by certain characterisics
- ex female nurses smoke and dont
- compares them in a particluar outcome
- may be combined as prospective cohort study
-
Case Study research
- detailed report of the diagnosis treatment and follow up of an individual patient
- contain some demorpgraphic information
- age,gender,ethnic origin
-
Retrospective Research
- compares two groups of people
- those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition (controls)
- study medical,lifestyl histories, factors may be associated with disease
-
Meta-Analysis
- combines the reults of several studies that address a set of related research hypotheses.
- Will include number of articles reviewed and otucome sof each to reach a summar conlusion
-
Review
summary of research on a particular subject
-
Basic Research
- Pure fundamental
- increase a body of knowledge
- explore unknown
- not necessarily solve a problem
- ex- studying the structure of a vitamin
-
Applied Research
- takes known information and attempts to solve
- ex- effects of a low fat diet on hear disease
-
Control Group
- is given the traditional or standard care or medication
- may be given placebos
-
experimental group
receives the treatmetn or medication that is being tested
-
Dependent Variable
- the variable that is of interest to researchers
- ex HDL cholesterol
-
Independent variable
- the variable that is being manipulated by researchers
- ex fiber intake
-
Bias
- is the distortion of results caused by some factor other than the study itself
- can be caused by researchers
- or by subjects
-
Open Label A
situation when both the researcher and the participant know the study
-
Open Label
opposite of double blind neither hte researcher nor the participant knows
-
Single/blind Study
- subjects are unawar if in control or experimentak
- only researcher knows
-
double Blind study
both the subjects and researchers are unaware
-
Placebo Effect
this happens when subjects feel better just because they are involved in the study even if they are receiving the placebo
-
Replication
same study but different researchers and participants
-
duplication
same study same results
-
positive correlation
more calories you eat more you gain weight
-
Sections of articles
- Abstract
- introduction
- review of literature
- methodology
- results
- conclusions
- references
-
ADA
- position papers explain the associations stands on issues that affect the nurtitional status of the puplic.
- positions staements and support paper based on sound scientific data
-
validity
- measure what you should be measuring
- real accurate results
-
Peer or refered articles
- scientist rigoursly evaluates a research study to assure
- original article
-
reliable sources of nutrition
- professional oganizations
- american dietetic association
- american society for nutrition sciences
- american soceity for clinical nutrition
- society for nutrition education
- american college of sports medicine
- nort american association for study obesity
-
reliable sources of nutrition continued
- journals
- educational instituions
- persons with credible credentials
- hospitals and clinica
- libraians books
-
Common health Frauds
nutritional schemes
-
FAD diets nutritionally inadequate
- become vary popular temp
- special apeal or prestige
- sound easy
- little responsibilities
- distort or ingore basci nutition
- seldom include full variety of foods
-
Checklist for nutrition misinformation
- is something being sold
- does if offer a quick fix
- are catchy
- are testimonalrs
- does it sound to good to be true
- is money back gurantee offered
-
Using ADA evidenc based library
- experts have crtically reviewed articles for you
- summary and conlusions
- strenghts and weakness of each article
-
What is a healthful body Weight
- appropriate for tour age and physical development
- maintained withoud dieting
- family hostory of body shape and weight
- good eating habits and physical activity
- acceptable to you
-
underweight
habing too little body fat to maintain health
-
overweight
habing a moderate amount of excess body fat
-
Obese
having an excess of body fat that adversely affects health
-
Morbid obesity
body weight exceeding 100% of normal, creating a very hogh risk for serious health complications
-
Body mass index
- expresses the ratio of a persons weight to their height
- BMI values below 18.5 or above 30 have increased health risk
-
BMI Calculation
Weight (lbs)x703/height in inches2
-
Limitations of BMI
- it may overestimate body fat in athletes and others who have a muscular build
- underestimat body fat in older persona ans others who have less muslce mass
-
Underweight
- BMI below 18.5kg/m2
- increases the risk of infections and illness and can even be fatal
- can be just as unhealthy as overweight
-
overweight
- BMI between 25 and 29.9 kg/m2
- health risk
- hogh blood pressure
- heart disease
- type 2 diabetes
- sleep disordors
-
Obesity and Morbid Obesity
- Obesity BMI between 30 to 39.9kg/m2
- Morbid obesity exeeds 100% of normal and or BMI>40
-
Overweight and obesity
- epidemic in US linked to many chronic disease
- hypertension
- dyslipidemia
- type 2 diabetes
- heart disease and stroke
- gallbladder disease
- sleep apnea
- steoarthritis
- gestational diabetes
- depression
-
Obestity and chornic disease
- heart disease
- all cancers: colon breast endometrial and gallbladder
- stroke
-
Body Composition
measuement of body fat and lean muscle mass
-
Densitometry
underwater weighing
-
Anthropometry
measurment of skinfold thickness using skinfold calipers of body circumferences
-
conductivity
bioelectric impedance
-
DEXA
considered the most accurate
-
Bod Pod
air displacemetn (plethysmography) expensive
-
The mosh inaccurate measuremt available
- Skinfold measurement
- dependent on person taking measurements and degree of training
-
Bioelectric impedance
- depends upon several factors
- hydration
- least invasibe and fairly accurate
-
Fat distribution Pattern
measured by waist to hip ratio and waist circumference
-
Apple shaped fat patterning
- upper body
- increased risk for chonic deseases
- android-men-visceral fat apple
-
Pear shaped fat patterning
- lower body
- no significant increased risk for chornic desease
- ganoid-woman
-
Waist to hip ratio
- WHR= waist circumference/hip cicumference
- desirable values
- <0.80 women
- <0.90 men
- high= central obesity
-
Waist circumference
- risk of death
- chronic disease from all causes appears to be highest for individuals with central obesity which
- > 40 in males
- >35in females
-
Gaining or lossing weight
- depens on
- energy intake vs energy expenditure
- genetics
- childhood weight
- behavior/lifestyle
- social factors
-
Energy balance
occurs when energy intake =energy expediture
-
Energy intake
- calcualting energy that is in a particular food
- grams of prtoein or carbs or fat x kcal of coresponding energy
- add together which = total kcal
-
Weight gain results
- when total daily energy intake exceeds the amount of energy they expend
- an excessive intake of aprox 3,500 kcal will result in a gain of one pound
- without exercise will be likely fat
-
Basal Metabolic Rate(BMR)
- energy expended to maintain basal ,or resting functions of the body
- the highest protion of energy expenditure
-
BMR increases with
- more lean body mass,during stress, and period of growth
- hogher lean body mass
- greater height
- younger age
- elevated levels of thyroid hormone
- stress fever ilness
- male gender
- pregn and lactation
- drugs caffeine tobacco
-
BMR Decreses with
- older age and during energy restriction
- fasting or starvation
- lower lean body mass
- lower height
- depressed levels of thyroid hormone
- female gender
-
Basal Metabolism Rate (BMR)
- energyt used to maintain life when the awake body is at complete rest
- circulation
- respiration
- temperature maintenance
- synthesis of new tissue
- nerve activity
- hormone secretion
-
Energy Out Balance
- BMR=60-75%
- TEF(thermic EFfect of foods)= 5-10%
- Physical Activ=15-35%
-
Energy Expediture Measurment
- 1. Direct calorimetry is the method that amount of heat the body releases
- 2. Indirect Calorimetry estimates energy expenditure by measuring oxygen consumption and carbon dioxide production
- used in hospitals
-
Prevalence of obesity
- nearly two thirds of US adults are overwieth
- Nearly one third of US adults are obese
- 1 in 5 children are obese
- less than 1/2 have a healthy weight
-
Causes of Obesity
- Diet
- Inactivity
- physchological factors
- genetics/environment
- age
- medication
- medical problems
-
Genetic Factors
- about 25%
- thrify gene theory
- set-point theory
-
Thrifty Gene Theory
- proposes that a gene or genes cases people to be energetically thrifty
- expend less energy than other people and therfore gain weight
-
Set-Point Theory
proposes that each persons weight stays within a small or narrow range set point
-
Leptin Theory
leptin is a hormone produced by fat cells that casues reduced food intake reduced weight ,decreased body fat
-
Physiologic Factors
- Hunger vs appetite
- leptin - reduce food intake/less effect in obese
- Ghrelin-stimulate appetite hour later hungry after eating
- Peptide yy(pyy)- decreases appetite relasased in the GI
-
ChildHood Factors
- environmental factors in childgood can influence
- childhood overweight inceases the risk of heart desease and premature death as an adult
-
compositon of the diet
theory states that overeating dietary fat promotes storage as adipose tissue / as well as carbs and protein
-
Social Factors
- influencing our diet
- family
- culture
- holidays
- easy acess
- less physical act
- societal expectations perfect body
-
Co-Morbidites related to obesity
- hypertension
- diabetes
- dyslipidemia abnormal blood fats- usually from diet hogh in saturated fat high ldl,low hdl, hogh triglycerides
-
Co morbidities related to obesity continues
- coronary artery disease
- stoke
- gall stones
- gout
- osteoarthritis
- sleep apnea
- cancer
-
Fad Diets
fads that do not results in long term healthful weight changes
-
Sugar busters
- basic conepts is all sugars, including sugar derived form colplex varbohydrates and starches ar toxic
- potatoesmcornmcarrots
- recommended for children prengant women diabetics
- protein and fats should be limited
-
Raw food diet
- cooked food lose the natural vitamins nutrients and enxyme snecessary to build a strong immune system
- only fruits and vegetable picked ripe
- professional anaylysis of this diet
- restrictions make difficult to get nurtients needed
- example b12 and D
-
Eat rigth 4 your type
- type A vegetarians
- type b omnivores
- groups people based only on blood type and does not consider individual variences
-
The Flavor Point diet
- workd to sudue appetit on two levels
- flavor
- minimally processed foods
- nutritionally sound but avoid taking the concept too far and becoming too restrictive
-
Weight loss diets
- high fat low carboydrates,high on protein diets
- cause ketosis
- nutritionally inadequate,require supplements
-
Atkins diet and New Atkins Diet
- mostly protein
- high protein
- low carbs
- major restrictions on cabohydrates
- ketones buildup
- increased intake of sat fat and cholest
- contradicts everhting we know about health promotion and disease prevention
-
Moderate fat,high carbs, moderate protein diets
- gradual weight loss
- effective in weight loss
- decrease in ldl
- decrease in TG
- decrease in Blood presur
- nutritionaly adequate if follow general guidelines
-
South Beach Diet
- 3 phases
- theory is that faster sugars and starches are digested the more weight is gained
- 1400-1500 calorie intake
- first phase unhealthy
- compliant many fo the foods and recipes are not common to all areas
-
The Zone
- 40 cho 30 pro 30 fat 4:3
- closer to what most dietetic profesionas recommend
-
Behavior Modification
- Most successful of all therapies
- self monitoring
- control
- cognitive restructuring
- aims change lifestyle
-
Individual Approaches
- helpful for figuring meal preration new recipes
- nurtrient and k cal count s
- may be expensive
-
Low fat and very low fat diets
- regular physical activity is a key component
- effective at weight loss but difficult ot mantain over time because they are too restrictive
- about 11-19% of total
-
FAD Diets
- Starvation
- Very low calore diets <800 kcal
- restricted diets 800-1600 kcals
-
Adipose tissue
- storage site of body fat
- 1lb of fat = 3500 kcal
- 5 lb = 17,500 kcal
- to lose 5 lbs of fat in a week
- 17,500kcal / 7 days = 2,500/day
-
Appropiate weight loss
- no more than 1-2 lbs per week
- to lose 1lb 3500/7=500 kcals per day
- to lose 2lbs 7000/7=1000 kcals per day
-
Weight loss medications
- should only be used if a person has
- BMI of 30kg/m2
- BMI of 27 kg/m2 and other health risk factors
-
Effective weight gain
- east 5500 to 1,00 extra kcal
- eat frequently
- limit fat 15-30%
- exercise regularly with resistance training in order to gain lean muscle tissue
-
Wight control diet
- East less sugar and high sugar foods
- 1 less 12 oz can of soda per day = a weight loss of about 15lbs in one year
-
Effect of Exercise
- increase metabolic rate or prevent decline due to calore restrictions
- rduce fat mass
- incrase in HDL-C
-
Treatments for obesity
- low calorie diet
- regular exercise
- prescription medication
- surgery
-
Medications
for people with a BMI >30 or 27
-
Meridia (sibtramine)
- decreases appetite by altering brain neurtransmitters
- side effects = increased blood pressure,dry mouth, anorexia, constipation,insomnia, dizziness,nausea
-
Xenical (orlistat)
- inhibits pancreatic lipase and decreases fat abosrption
- side effects = abdominal pain, fatty and loos stool,leaky stools, flatulence, decreased absorption of fat solubl nutrients
-
Alli-over the counter orlistat
possible side effects the wall steet journal
-
Surgery
- only for morid obesity
- new researth suggest that this surgery should be done before DM,CVD,etc are sever
-
Surgery Qualification
- BMI 35+ and
- 2 co morbidities = diabetes,CVD or sleep apnea or
- BMI 40+
-
Gastric Banding
- uses a premeasur prosthetic device to restrict oral intake
- usually 0.5 com
- can adjust
- muche better with flexible band
- less consistent than other banded
-
Gastric Bypass
- combines gastric resection with small amount of sub-clinical malabsorption
- iron, B12
- mean weight loss 35%
-
Biliopancratic bypass BPB
- modest amount of gasrtic restriction with intenstinal malabsorption
- entire jejunum is excluded
- metabolic complication in the first year
- anemia
- fat soluble vitamin deficiencies
- treatment of protein calore malnutrition
-
Gastric Bypass Sleeve
- sleeve is new stomach pouch no chang to the anatomy
- have less stomach stomach still attached to small intestine
- still post surgery diet requirements
- least amount of nutrient lost
-
Complication of gastric surgery Possible
- death
- lung problems
- infection
- heart complicatin
- leaks in GI
- blood clots
- post op ulcers
- obstruction and strictures
-
Early complications
- wound infection
- dificiency anemia
- dumping sydrome
- blood colt
- walking blood thiners
- bowel obstruction
-
Early Potential
- respiratory problems biggest risk
- anastomotic leak
-
Tachycardia
- Possible causes leakage
- uncontrolled pain
- hypervolemia
- hemorrahage
-
Pulmonary embolism
- primary cause of motrality after bariactric surgery
- early ambulation necessary
- stenosis
-
Stricture
- narrowing bleeding at anastomosis
- rature or leakage from staple lines
-
Long term complicatins
- vitamin B12 deficiencies
- iron anemia
- hypoalbuminemia
- ulcer at the gastrojen
- bile reflux
-
ulcers
at the site of the stomach or intestinal anastomosis or acid peptic ulcer in non functional large stomach pouch
-
gall stone
related to rapid weight loss more than surgery
-
Dumping syndrome
- most common cuases of morbidity after gastric surgery
- abnomality
- fatality
- gastriontestinal and vasomotor symptoms
- postprandial fullness
- crampy abdomonal pain
- nausea
- vomiting
- explosive diarrhea
-
Vastomotor symptoms(dumping Syndrome)
- sweating
- diaphoresis
- weakness
- dizziness
- flushing
- palpitations
- intense desir to lie down
-
Early Dumping syndrome
- starts 10-30 minutes after ingestion of a meal
- gastrointestinal and vasomoter compaints
-
Late dumping syndrome
- 2-3 hours postprandially
- mainly vasomotor response
-
dumping sydrome preventions
- increase complex carbs
- increase dietary protein
- eat small frequent meals
- eat dry meals , liquids on half hour after meal
- avoid simple sugars
- add fiber to diet
-
Fat Malabsorption
- in bypass operationthe fat obsorbing intestine is bypassed, this leads to malbsorption
- high fat meal cause diarrhea
- explosive and fouls smelling can last
- best to aboid high fat or greasy foods
-
Nutrients after surgery
- eat healthy manner, snacking
- adequat fluid intake
- take the multiple vitamin/mineral
-
Diet after surgery
- several phases
- phase 1 liquids only
- phase 2 soft or puree foods
- phase 2 and 4 normal foods
- varies in physician
-
Bariatric surgery nurtition guidlines
- 6 meals daily eat every 2-3 hours
- clear liquid 1-2 days after
- blended diet 2 weeks 1 month
- soft diet: 1 month 2 months
- solid diet 2 months
- meat size of pencil erasers
-
Bariatric surgery guidlines continued
- 30 minuts before and afgter meals
- limit soups, yougart
- limit caffein due to dehydtation
- avoid carbonated beverages discomfort
- stop eating and drinking when feelings of fullness occur
- avoid food with more than 2 gm sugar alcohol
-
Activity and exercise phychological effects
- increased energy
- less fatique
- improvements inbody image and self esteem
- emphasize walking and sweimming
- more otion available as weigh decreases
-
Outcomes of gastric surgery
- 50% considered successful
- is the best treatment for morbility obese
- measured by weight loss and improvement of obesity related medical disorders
-
Follow up surgeries
- possible leaks from first
- hernias are most common
- plastic surgery for excessive skin
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