-
H2 receptor antagonists (Blockers)
- Uses: GERD, peptic/duodenal ulcers, dyspepsia
- -used for stress uclers in hospitals
ADE:blur, optic neuritis, ocular irritation, N/V/D, rash.
Agents: Cimetidine (Tagamet), Ranitidine (Zantac), Famotidine (Pepcid)
-
Antacids
Uses: Gastric acid irritation
ADE: Electrolyte imbalance, toxic electrolytes in renal impairment, constipation, diarrhea
- Ca2+: mixed with other antacid ingredients
- Al3+: constipation
- Mg3+: diarrhea (milk of magnesia)
-
Metoclopramide (Reglan)
Uses: Reflux esophagitis, duodenal ulcers, gastroparesis
ADE: CNS effects, diarrhea, constipation, unspecified visual disturbances.
-
Proton Pump Inhibitors
Uses: GERD, gastric/duodenal ulcers, dyspepsia.
ADE: blur, optic neuritis, irritation, dry eye.
Agents: "prazole's" Omeprazole (Prilosec - OTC), Lanoprazole (Prevacid), Esomeprazole (Nexium), Pantoprazole (Protonix), Rabeprazole (Aciphex)
-
Inflammatory Bowel Syndrome
MOA: Anti-inflammatory
- Agents: Mesalamine (Asacol) - ASA asprin prodrug, eye pain, vision abnormalities.
- Olsalazine (Dipentum) - blur
- Sulfasalazine (Azulfidine)
|
|
