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kawasaki disease and immunizations
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kawasaki disease def
acute systemic vasculitis of unknown origin, assoc w spring cleaning
prevalence of kawa
infants and young children (18mo-5 yrs is pk incidence)
etiology of kawa
season-more common in winter or spring
possible infectious cause
race-originally found in asian pts but affects all
clinical pres of kawa
fever, bilateral nonexudative conjunctivitis
erythema of lips and oral mucosa
changes in extremities
rash-usually on extre
cervical lyphadenopathy
classical diag of kawa
fever for five or more days
four or more of the following (5):
changes in extrem
rash-skin peels off
conjunc
cracking of lips and oral cavity, strawberry tongue
cervical lymphadenopathy
goals of acute tx of kawa
reducing inflamm of coronary artery wall
preventing coronary thrombosis
goals of management long termkawa
preventing myocardial ischemia and infarction in those that develop aneurysms, tx all w possible diag
pharmacotherapy for kawa
IVIG-2gm/kg in a single inf(fever should come down rapidly)
asa-80-100mg/kg/d in 4 doses during acute , dec to 3-5 mg/kg/d until follow up shows no coronary artery changes at 6-8 wks after onset of illness
complications of kawa
coronary artery aneurysms primarily in untreated children
Part A-national vaccine injury compensation Act
provides details related to compensaion if injury occurs
part B
removes manufactureres from liability if injuries occur as long as full info regatding product is provided
part C
FDA must be notified within 7 days if an adverse rxn does occur
documentation of vaccines
manufacturer, lot, date of admin, name, address, title of person giving
Author
Ambestul
ID
13625
Card Set
kawasaki disease and immunizations
Description
kawa
Updated
2010-04-08T23:36:00Z
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