-
Echinacea
what is it used for?
MOA
drug interactions
- decrease cold duration
- immunostimulant
- increases leukocytes, inhibits COX
- avoid taking w/ NSAIDs, increased risk for GI bleed
-
Gingseng
what does it do?
toxicities? drug interactions
- use: CV, hyperglycemia, energy
- interactions w/ antipsychotics, oral anticoagulants, caffiene, MAOI
- SE: schizophrenia, inhibition of platelet aggregation, increased bleeding
-
Ginkgo Biloba
uses?
interactions:
- Use: claudication (reduce ischemia from blood clot), dementia (ALZ pts), cerebral insufficiency
- Drug interactions:
- warfarin, NSAIDS, clopidogrel, decreases nifedipine & omeprazole, increased sedation w/ trazadone
- Side effects: SZ, bleeding
-
Garlic
Use:
drug interaction
Side effect
- Use: cholesterol lowering agent
- drug interactions: oral coagulants, HIV drug metabolism
- SE: bleeding
-
St. John's Wort
Use:
drug interaction
Side effect
- Use: anti-depressant
- Drug interaction: induces CYP3A4 (increases metabolism w/ many drugs), interacts w/ other anti-depressants - serotonin syndrome
- side effect: mild- headache and upset stomach,
-
Peppermint
use:
drug interactions
side effects
- use: GI discomfort, cough, tension headache (topical headache)
- drug interaction: inhibits CYP3A4
- Side effects:
- at low doses - headache, dizziness, muscle tremor, anal burning
- high dose: brain damage, gallbladder disease, skin damage, kidney damage
-
Ginger
Use:
Drug interactions:
Side effects:
- Use: hyperemesis gravidarum (super barfing during pregnancy), antiplatelet agent, migraine
- Drug interaction: anti-coags like warfarin
- Side effects: well tolerated
-
Soy
Use:
drug interactions
side effects
- use: high cholesterol, acute diarrhea in kids, menopausal sx
- drug interactions: aromatase inhibitors, possible warfarin
- side effects: decrease thyroid hormone, migraine, pancreatitis, estrogen like effects.
-
chamomile
use:
drug interactions:
side effects
- use: nausea, irritable bowel, dysmenorrhea, peptic ulcer, nervous system disorders
- drug: oral anticoag
- Side effects: decrease iron absorption , increased bleeding
-
Kava Kava
use:
drugs interactions
side effects
- use: anxiolytic
- drug interactions; benzo, barbs, ethanol, antihistamines, anesthetics, antipsycholtocs
SE: serious heptatoxicity, extrapyramidal effects, dermopathy, hair loss, hearing loss.
-
Saw Palmetto
use:
drug interactions
side effects
- use: pee probs, BPH
- drug interaction: warfarin
- side effects: nausea, hypertension, headache, urinary retention, abdominal pain
- contraindicated in pts w/ breast cancer, estrogen replacement, pregnant and lactating
-
Milk thistle
use:
drug interactions
side effects
- use: hepato protectant- esp mushroom poisoining and EtOH liver
- drug interactions: several CYPs
- well tolerated
-
Feverfew
use
drug interactions
side effects
- use: migraine, arthritis
- drug interactiosn: anti coags, anti platelet drugs
- side effects: mouth ulcers, GI upset, external dematitis
-
Horse Chestnut seed
use:
drug interactions
side effects
- use: chronic venous insufficiency and hemmeroids
- Drug interactions: oral anticoags
- SE: renal and blood toxcity, not safe at high doses
-
Bromelain Pineapple enzyme
use:
DI
SE
- use: sinusitis, inflammation
- DI: anticoags,
- SE:GI upset and hypersensitivity
-
Chasteberry
use:
DI:
SE:
- use: hyperprolactinema, mentrasual complaints
- DI; none
- SE: rash, GI upset, don't use for pregnant and lactating woman
-
Black Cohash
use:
DI
SE
- use: breast cancer, menopause, migranine
- DI- none
- SE- acute hepatitis, N/V, dizziness, nervous system
-
Comfrey
use:
DI:
SE:
- use: digest aid, wound healing, inflammation, myalgia
- DI : none
- SE: hepatotoxic
-
Greater Celandine
use
DI
SE
- use: cancer, biliary colic
- drug interactions - none
- SE: acute cholestatic hepattis, stomach pain, urinary urgency, hematuria, stupor
-
Mistletoe
use:
DI
SE
- use; cancer treatment
- DI- none
- SE: chils, fever, orthostatic hypotension, chest pain
-
Valerian
use
DI
SE
- use: sedative hyponotic
- DI: EtOH, Barbs, Benzos, anesthetics
- SE: decreases Fe absorption (tannin containing), sedation
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