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a potentially life-threatening condition caused by partial or complete failure of adrenocortical function with loss of the functions of the adrenal cortex and decrease in glucocorticoid, mineralocorticoid, and androgenic hormones. It is a chronic disease of hyposecretion of steroids
Addison's disease
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the outer portion of the adernal gland
adrenal cortex
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an acute, life threatening state of profound adrenocortical insufficiency requiring immediately medical management.
adrenal crisis
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it is fluid volume, hyponatremia, and hyperkalemia
adrenal crisis
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the inner portion of the adrenal gland
adrenal medulla
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a mineralocorticoid hormone produced by the adrenal cortex that acts on the renal tubule to regulate sodium and potassium balance in the blood
aldosterone
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the general anatomic term for the outer layer of the body or gan or other structure
cortex
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any of the natural or synthetic adrenocortical hormones; that is, those produced by the cortex of the adreanl gland
corticosteroids
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a metabolic disorder characterized by abnormally increased secretion of the adrenocortical steroids
cushing's syndrome
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an adrenegic hormone, also secreted by the adrenal medulla
norepinephrine
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increases blood pressure by causing vasoconstriction but does not appreciably affect cardiac output
norepinephrine
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it is the immediate metabolic precursor to epinephrin
norepinephrine
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a major group of corticosteriod hormones that regulate electrolyte and water balance
mineralocorticoids
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in humans the primary mineralocorticoid is aldosterone
mineralocorticoids
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a general anatomic term for the most interior portion of an organ or structures
medulla
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a negative feedback system involved in regulating the release of corticotropin-releasing by the hypothalamus, adrenocorticotropic hormones (corticotropin) by the pituitary gland, and corticosteroids by the adrenal glands.
Hyypothalamic-pituitary-adrenal (HPA) axis
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suppression may lead to addison's disease and possible adrenal crisis or addisonian crisis.
Hypothalamic-pituitary-adrenal (HPA) axis
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the suppresion results from chronic disease or exogenous sources, such as long-term glucocorticoid therapy
Hypothalamic-pituitary-adrenal (HPA) axis
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a major group of corticosteriod hormones that regulate carbohydrate, protein, and lipid metabolism and inhibit the release of adrenocorticotropic hormone (corticotropin)
Glucocorticoids
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an endogenous hormone secreted into the blood-stream by the adrenal medulla
epinephrine
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a synthetic drug that is an adrenergic vasoconstrictor and also increases cardiac output
epinephrine
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