-
Mannitol
- Osmotic Diuretic
- Osmitrol-IV
- Used for head injury (reduce cerebral edema)
-
Glycerin
- Osmotic Diuretic
- Osmoglyn-PO
-
Isosorbide
- Osmotic Diuretic
- Ismotic-PO
-
Acetazolamide
- CAIs
- Diamox
- Open-angle glaucoma, Acute mountain sickness
- Causes Metabolic Acidosis, renal stone formation, ammonia circulation (hepatic)
-
Methazolamide
- CAIs
- Glauctabs
- Open-angle glaucoma, Acute mountain Sickness
- Causes Metabolic Acidosis, renal stone formation, ammonia circulation (hepatic)
-
Furosemide
- Loop
- Lasix-PO, IV
- High protein bound, 50% kidney glucoronidation
- Short t1/2(1-3hr), hypokalemic alkalosis,Ototoxicity, hyponatremia, hyperuricemia-gout, hypomagnesemia
-
Bumetanide
- Loop
- Bumex-PO, IV
- High PO absorption, Hepatically metabolized
- Short t1/2(1-3hr), hypokalemic alkalosis,Ototoxicity, hyponatremia, hyperuricemia-gout, hypomagnesemia
-
Torsemide
- Loop
- Torsemide- PO, IV
- High PO absorption, Hepatically metabolized
- Short t1/2(1-3hr), hypokalemic alkalosis,Ototoxicity, hyponatremia, hyperuricemia-gout, hypomagnesemia
-
-
Chlorothiazide, Hydrochlorothiazide, Methyclothiazide, Polythiazide
- Diuril, Hydrodiuril, Enduron, Renese
- Na/Cl Symporter of DCT
- Hypokalemia, Hypovolemia, Hyponatremia,Hypercalcemia, Hypomagnesemia, decreased glucose tolerance, increase cholesterol, TG level, Impotence
- Usage: Edema (ineffective at GFR<30), Hypertension
-
Chlorthalidone
thiazide-like
-
-
-
Amiloride
- K-sparing Diuretics
- ENaC of principal cells of late DCT and collecting duct
- Usage: HTN, Edema, Liddle's Syndrome
-
Triamterene
- K-sparing Diuretics
- ENaC of principal cells of late DCT and collecting duct
- Usage: HTN, Edema, Liddle's Syndrome
-
Spironolactone
- MR antagonist
- Basolateral side of renal epithelial cells
- Usage: Edema, HTN, Hepatic cirrhosis, HF
-
Eplerenone
- MR antagonist
- Basolateral side of renal epithelial cells
- Usage: Edema, HTN, Hepatic cirrhosis, HF
|
|