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Extractions
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Define
amphoteric
A compound which contains both acidic and basic functional groups
Define
solubility
• The capacity of two or more substances to form, without chemical reaction, a homogenous molecular dispersion
Define
Acid
A compound which can donate a proton
Define
Base
A compound which can accept a proton
Define
solvent
the liquid componet into which the solute is dissolved
Name one source where chemical information, such as solubility, melting points, etc, can be found.
Merck index or Clark's
isolation and identification of drugs
Name 3 types of extractions.
Dry Extractions
• Liquid-Liquid extractions
• ANOR Extractions
Name 2 of the common solvents used in extractions.
chloroform
diethyl ether
petroleum ether
ethyl acetate
What extraction technique can be used specifically for methamphetamine and amphetamine?
What chemical property makes this extraction work?
Alkaline Diffusion
Takes advantage of the volatile nature of a drug in its base form
Drugs in the basic (ionic) state tend to be __________ in water while their salt forms tend to be __________ in water.
insoluble
soluble
True or False
Sugars are typically soluble in organic solvents.
True
True or False
Tablet binders are typically insoluble in organic sovents.
True
True or False
When determining solubility based on polarity, the general rule that can be applied is "like dissolves like".
True
True or False
Liquid-liquid extractions are the simplest type of extractions.
False
Dry extractions
What is a solute?
The compound that is dissolved in a liquid solvent
True or False
Cocaine base is soluble in petroleum ether, and cocaine HCl is soluble in chloroform.
True
Author
abbyljones9
ID
135237
Card Set
Extractions
Description
Test #2
Updated
2012-02-27T01:44:40Z
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