-
Lovenox
- Gen: Enoxaparin Sodium,
- Class: Anticoagulant (LMW-heparin),
- RoA: IV,
- MOA: Anti-Factor Xa and anti-thrombin (Factor IIa) activity,
- Indication: DVT, PE, MI, Ischemia, (all postop and prophylaxis)
-
Aranesp
- Gen: Darbepoetin Alfa,
- Class: Erythropoietic- Hematopoietic,
- RoA: IV or SC,
- MOA: stilmulates progenitor stem cells for production/differentiation of erythropoiesis,
- Indication: Anemia from Chronic Kidney Disease and Chemotherapy
-
Procrit
- Gen: Epoetin Alfa,
- Class: Erythropoietic- Hematopoietic,
- RoA: IV or SC,
- MOA: stimulates bone marrow division/differentiation of committed erythroid progenitors,
- Indication: Anemia from Chronic renal failure, Chemotherapy, or Surgical procedures
-
Revlimid
- Gen: Lenalidomide,
- Class: Immune Modulator (antiangiogenetic),
- RoA: Oral,
- MOA: inhibits cell proliferation, pro-inflammatory cytokines,
- Indication: Multiple myeloma, Myelodysplastic syndrome
-
Neulasta
- Gen: Pegfilgrastim,
- Class: Colony Stimulating Factor(CSF), Hematopoietic,
- RoA: SC,
- MOA: A CSF- stimulates proliferation/differentiation/ activation of hematopoietic cells,
- Indication: Febrile neutropenia, in pt with non-myeloid malignancies, Prophylaxis
-
Remicade
- Gen: Infliximab,
- Class: Immunosuppressant (TNFa-I),
- RoA: IV infusion,
- MOA: inhibits the binding of TNF alpha,
- Indication: Crohn's, Colitis, RA, psoriasis
-
Rituxan
- Gen: Rituximab,
- Class: Antineoplastic agent, (Mab),
- RoA: IV infusion,
- MOA: binds to CD20 antigen located on pre-B lymphocytes and may promote lysis,
- Indication: Lymphomas, Leukemias, RA
-
Levaquin
- Gen: Levofloxacin,
- Class: Antibiotic (fluoroquinolone),
- RoA: Oral , IV, optical,
- MOA: inhibits topoisomerase IV, DNA gyrase (replication, transcription, repair, recombination),
- Indication: Bronchitis, Pneumonia, UTI, (Anthrax)
-
Avastin
- Gen: Bevacizumab,
- Class: Immunomodulator, Antiangiogentic, (Mab) VEGF-I,
- RoA: IV infusion,
- MOA: IgG1 antibody Binds to VEGF to inhibit VEGF/Flt1 & KDR interaction of epithelial cells
- Indication: Glioblastoma, Cancer (Colorectal, Renal cell Small cell lung)
-
Zosyn
- Gen: Piperacillin Sodium/Tazobactam Sodium,
- Class: Antibiotic (antipseudomonal/B-lactamase-I),
- RoA: IV infusion,
- MOA: Transpeptidase-I/ B-lactamase-I ,
- Indication: Appendicitis, Pneumonia, Skin infection, Peritonitis, Puerperal endometritis
-
Neupogen
- Gen: Filgrastim,
- Class: Colony Stimulating Factor, Hematopoietic,
- RoA: SC,
- MOA: granulocyte CSF, regulates neutrophil production, progenitor proliferation, and differentiation,
- Indication: Febrile neutropenia, harvesting peripheral stem cells
-
Eloxatin
- Gen: Oxaliplatin,
- Class: Antineoplastic Agent, Platinum Coordinating Complex
- RoA: IV,
- MOA: binds nucleotides to inhibit DNA replication of tumor cells
- Indication: Colon cancer - stage III, colorectal cancer
-
Diprivan
- Gen: Propofol,
- Class: Sedative/Hypnotic, Anesthetic,
- RoA: IV,
- MOA: unknown,
- Indication: General anesthesia, Sedation for mechanically ventilated
-
Omnipaque
- Gen: Iohexol,
- Class: (dye)Non-Ionic Contrast Agent,
- RoA: IV,
- MOA: hypotonic, low osmolality to serum,
- Indication: Diagnostics radiology
-
Integrilin
- Gen: Eptifibatide,
- Class: Anticoagulant, Glycoprotein-I (2b/3a)
- RoA: IV,
- MOA: inhibits platelet aggregation by binding to GP2b/3a - prevents binding of fibrinogen, vWf, and other adhesive ligand,
- Indication: Acute coronary syndrome, percutaneous coronary intervention
-
Advair Diskus
- Gen: Fluticasone Propionate/Salmeterol Xinafoate,
- Class: Antiasthma, Anti-inflam/Bronchodilator Combo,
- RoA: Inhalation,
- MOA: Fluticasone: glucocorticoid receptor agonist. Salmeterol: long acting beta agonist, relaxes bronchial smooth muscles,
- Indication: Asthma, COPD
-
Sodium Chloride
- Gen: Sodium Chloride,
- Class: Dermatological Agent, Parenteral Electrolyte, Sodium Supplement,
- RoA: Inj, IV, Topical,
- MOA: principle cation of extracellular fluid,
- Indication: Corneal edema, Elective abortion, Heat stroke, Hyponatremia, Hypovolemic shock, Nasal irritation
-
Zyvox
- Gen: Linezolid,
- Class: Antibiotic (Oxazolidinone),
- RoA: IV
- MOA: inhibits ribosomal translation by binding to 23S of 50S RNA, Preventing 70S complex formation
- Indication: Pneumonia, Vanco-resistant Enterococcus faecium infection, infection of skin
-
Herceptin
- Gen: Trastuzumab,
- Class: Antineoplastic Agent, Mab (HER2-I),
- RoA: IV,
- MOA: monoclonal antibody binds to HER2 protein to inhibit the growth of tumor cells,
- Indication: Metastatic breast cancer, HER2 overexpression
-
Protonix
- Gen: Pantoprazole Sodium,
- Class: PPI,
- RoA: Oral, IV
- MOA: inhibits acid secretion by covalently binding to the H/K ATPase pump,
- Indication: GERD, Zollinger-Ellison Syndrome, Gastric hypersecretion
-
Taxotere
- Gen: Docetaxel,
- Class: Antineoplastic Agent (Mitotic-I),
- RoA: IV,
- MOA: binds/inhibits microtubule disassembly inhibiting mitotic/interphase = no cell division,
- Indication: Breast cancer, Gastric cancer, Head & neck cancer, hormone refractory prostate cancer, lung cancer
-
Angiomax
- Gen: Bivalirudin,
- Class: Anticoagulant, Thrombin-I,
- RoA: IV,
- MOA: binds to catalytic site and the anion-binding exosite of circulating and clot-bound thrombin,
- Indication: Heparin-induced thrombocytopenia, Thromboembolic disorder
-
Thrombin-jmi
- Gen: Bovine Thrombin,
- Class: Hemostatic, Coagulant,
- RoA: Topical,
- MOA: a protein substance that immediately clots the fibrinogen of the blood,
- Indication: hemorrhage
-
Cancidas
- Gen: Caspofungin Acetate,
- Class: Antifungal, Glucan Synthesis I,
- RoA: IV,
- MOA: inhibits beta-1,3-D-glucan synthesis: an important component of cell wall,
- Indication: Aspergillosis, Candidemia, Febrile neutropenia
-
Ultane
- Gen: Sevoflurane,
- Class: Anesthetic, Haloalkane,
- RoA: Inhalation,
- MOA: disrupts lipid matrix of neuronal membranes affecting gating of ion channels,
- Indication: General Anesthesia
-
Seroquel
- Gen: Quetiapine Fumarate,
- Class: Antipsychotic, Dibenzothiazepine,
- RoA: Oral,
- MOA: antagonist of 5-HT1A, 2, D1,2, H1, and alpha1,2,
- Indication: Bipolar-1, MDD, Schizophrenia
-
Protonix IV
- Gen: Pantoprazole Sodium,
- Class: PPI,
- RoA: Oral, IV
- MOA: inhibits acid secretion by covalently binding to the H/K ATPase pump,
- Indication: GERD, Zollinger-Ellison Syndrome, Gastric hypersecretion
-
Gemzar
- Gen: Gemcitabine Hydrochloride,
- Class: Antineoplastic Agent, Antimetabolite
- RoA: IV,
- MOA: nucleoside analogue cell phase-specific for the S-phase and for the G1/S-phase, inhibits DNA synthesis,
- Indication: Breast, Ovarian, Pancreas, non-small cell lung cancers
-
Erbitux
- Gen: Cetuximab,
- Class: Antineoplastic agent, (Mab) EGFR-I,
- RoA: IV,
- MOA: binds EGFR blocking phosphorylation/activation of kinases, inhibiting growth/survival of tumor cells
- Indication: Head and neck cancer, Metastatic colorectal cancer
-
Visipaque
- Gen: Iodixanol,
- Class: (Dye)Non-Ionic Contrast Agent
- RoA: IV,
- MOA: hypotonic, low osmolality to serum,
- Indication: Diagnostics Radiography
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