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Guillain-Barre' Syndrome
- destruction of myelin sheath by immune system
- starts at legs & moves up (ascending paralysis)
- may require mechanical ventilation
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Guillain-Barre' Syndrome-three stages
- Acute or initial period-begins at onset and ends when no further deterioration occurs
- Plateau phase-disease just "hangs around", doesn't get better or worse
- Recovery phase-remyelination and axonal regeneration
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Guillain-Barre' Syndrome-assessment
- get symptoms in chronological order
- pain
- cranial nerves: smile, frown, whistle, drink
- speak
- cough
- increased WBC's and protein in CSF
- respiratory function compromised
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Guillain-Barre' Syndrome-interventions
- plasmapheresis-remove excessive plasma
- IV immunoglobulin
- DO NOT USE Corticosteroids
- RESPIRATORY IS PRIORITY! Keep mechanical ventilator handy
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