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What forms the blood brain barrier?
Astrocytes
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Cerebrum - brain functions?
- conscious thought processes, intellectual functions
- -memory storage and processing
- -conscious and subconscious regulation of skeletal muscle contractions
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cerebellum - functions
- coordinates complex somatic motor patterns
- -adjusts output of other somatic motor centers in brain and spinal cord
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pons - functions
- relays sensory info to cere bellum and thalamus
- -subconscious somatic and visceral motor centers
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medulla oblongata functions
- -relays sensory info to thalamus and to other portions of the brain stem
- -autonomic centers for regulation of visceral function (cardiovascular, respiratory, and digestive system activities)
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mesencephalon functions
- processing of visual and auditory data
- -generation of reflexive somatic motor responses
- -maintenance of consciousness
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hypothalamus functions
centers controlling emtions, autonomic functions, and hormone production
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thalamus functions
relay and processing centers for sensory info
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7 major divisions of CNS
- 1. cerebral hemisphere
- 2. diencephalon
- 3. Midbrain
- 4. Pons
- 5. Cerebellum
- 6. Medulla
- 7. Spinal cord
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Spinal cord
- -flow of info from PNS to CNS
- -direct body movement
- -processes sensory info from limbs, trunk, and internal organs
- 0segmental organization and pair of nerve roots
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Brainstem =
medulla + pons + midbrain
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spinal cord
- head (sensory, motor control)
- -use of cranial verves in place of spinal nerves
- -transmission of info between brain and SC
- -regulation of arousal and viscceral functions (bp & respiration)
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Cerebellum
regulation of movement, maintenance of posture and balance; works closesly in concert with pons
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thalamus is the key...
..for transmitting info to cerebral hemispheres
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Hypothalamus ...
- integrates functions of the ANS
- -controls endocrine hormone release from pit
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cerebral cortex convoluted to accommodate large surface area. ..
gyri, sulci, fissues, and 4 lobes
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Frontal lobe.
- -motor behavior
- -primary cortex at precentral gyrus: nearby premotor areas, prefrontal assocaiton cortex, cingulate gyrus (import. for reasoning and emotional)
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Parietal lobe.
- sensory areas.
- Primary cortex at postcentral gyrus
- -superior parietal lobule (spatial perception, self-image
- -inferior parietal lobule (integrating sensory info for speech and perception)
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Occipital lobe
- primary cortex within calcarine fissure on medial surface
- -surrounding association cortex elaborates the sensory message so that can see and integrate forms and colours
- -important for recognizing faces
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Temporal lobe
- sensory funccitons +memory and emotions
- -primary auditory cortex: on superior temporal gyrus - speech centre
- -integrate with nearby areas: inferior temporal gyrus: perception of visual forms and colours
- -works with nearby occipital
- -temporal pole + medial temporal areas: mediate emotions along with nearby frontal cortical areas
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Hippocampus important in ...
learning and memory
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Amygdala...
emotional control and coordination of rage
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whats the limbic system?
hippocampus and amygdala; important implications for psychiatry
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Basal Ganglia
imorant in control of movement, emotion and cognition
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CSF formation in CNS
- CSF surrounds and fills tubular CNS
- -serves as cushion and shock absorber
- -serves as medium for chemical communication
- -general structures serve as important landmarks for nearby structures: (lateral ventricles, 3rd ventricles, 4th ventricle)
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function of dura mater and what folds?
- STABILIZE THE POSITION OF BRAIN
- -falx cerebri, tentorium cerebelli, falx cerebelli
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Cranial Meninges of CNS.
-dura, arachnoid, pia
- -protective, circulating function (contain bloodvessels) - veings and arteries in subarachnoid space
- -dural sinuses - major venous areas carrying blood away from brain
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CSF
cushions delicate neural structures, supports brain, transports nutrients, chemical messengers, and waste products
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pathway of CSF
- -produced at choroid plexus
- -travels thru lateral and medial apertures to subarachnoid space,
- -diffuses across the arachnoid granulations itno the superior sagittal sinus
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BBB
isolates neural tissue from general circulation
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medulla oblongata
- connects brain with spinal cord
- -contains relay stations and reflex centers (olivary nuclei and cardiovascular and repiratory ryhythmicity centers)
- -reticular formation beingsi n medulla oblongata and extends into more superior portions of the brainstem
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Pons.
- -sensory and motor nuclei for four cranial verves
- -nuclei that help control respiration
- -nuclei and tracts linking cerebellum with the brain stem, cerebrum and spinal cord
- -ascending, descending, and transverse tracts
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reticular formation
analogous to intermediate zone; plays key role in sensory motor integration; regulates arousal
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Cerebellum
- adjusts postural muscles and tunes on-going movements
- -cerebellar hemispheres: anterior and posterior lobes, vermis, flocculonodular lobe
- -superior,m iddle and inferior cerebellar peduncles link cerebellum with brain stem, diencephalon, cerebrum, and spinal cord
- -interconnects the two cerebellar hemispheres
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Mesencephalon contains...
- corpora quadrigemina (superior and inferior colliculi)
- -contains many nuclei: red nucleus, substantia nigra, cerebral peduncles, RAS headquarters
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Diencephalon composes of
epithalamus, hypothalamus, thalamus
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Thalamus ...in terms of sensory info
final relay point for ascending sensory info
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Thalamus coordinates...
the activities of cerebral cortex
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thalamus is part of...
- diencephalon - relay nuclei thru which sensory and motor info pass to and from cortex
- EG. from sc to primary sensory cortex; from primary motor cortex to sc
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Thalamus - projecting nuclei
- diffuse; function in arousal and regulates various functions of cerebral cortex
- -final relay point for ascending sensory info
- -coordinates activities of cerebral cortex and basal nuclei
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internal capsule
white matter underling cortex; path of transmission of info immediate to and from cortex
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Hypothalamus.
- controls somatic motor activities at the subconscious lvl
- -controls autonomic function,
- -coordinates activities of endocrine and nervous systems
- -secretes hormones
- -produces emotions and behavioral drives
- -coordinates voluntary and autonomic functions
- -regulates body temp
- -coordinates circadian cycles of activity
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most cortical regions in humans are
advanced forms (neocortex, isocortex)
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paleocortex is
sense of smell, emotions (olfbulb)
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Archicortex
memories (hipp, 3 layers)
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Broadmann's Areas
thickness of each 6 layers varies between areas, whcih are also distinct functionally
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areas that subserve sensation have which layer?
- layer IV
- -primary motor areas have thick layer V
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White matter of the cerebrum
contains association fibers, commissural fibers, projection fibers,
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Basal nuclei
- caudate nucleus
- -globus pallidus
- -putamen:
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putamen:
control muscle tone and coordinate learned movement patterns
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primary motor cortex of the precentral gyrus directs...
voluntary movements
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primary sensory cortex of hte postcentral gyrus receives...
- somatic sensory info
- -touch, pressure, pain, taste, temp
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association areas...
- control ability to undersatnd sensory info and coordinate a response
- -somatic sensory asso. area
- -visual asso area
- -somatic motor assoc. area
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general interpretive area
- receives info from all sensory areas
- -present only in L hemisphere
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speech center
regulates patterns of breathing and vocalization
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prefrontal cortex
- coordinates info form secondar and special asso. areas
- -performs abstract intellectual functions
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hemispheric differences
L hemisphere typically contains general interpretive and speech centers and is reponsible for language based skills
R hemisphere: responsible for spatial relationships and analyses
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cranial nerves
- 12 pairs
- -each attaches to ventrolateral surface of brainstem near assoc. sensory or motor nuclei
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Limbic system (motivational system) includes
- amygdaloid body
- -cingulated gyrus
- -parahippocampal gyrus
- -hippocampus
- -fornix
- -functions: involve emotions and behavioral drives
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