-
Ranexa
- #Last line Stable Angina
- * QT prolongation
- ** inhibitors: grapefruit, PIs, Verapamil, Diltiazem,...
- Ranolazine
-
ReoPro
- GP IIb/IIIa inh = antiplatelet
- #ACS with Planned PCI within 24 hours.
- Use with Heparin.
- Abciximab
-
-
-
Pradaxa
- direct thrombin inh
- BID
- couple of hours gap with inh&ind
- if ECT not available then aPTT
- Dabigatran
-
-
Caduet
- CCB+Statin
- For HTN
- Amlodipine/Atorvastatin
-
Imdur
- Nitrate
- Don't Crush Imdur
- ISMN ER
- Isosorbide Mononitrate ER
-
Nitrostat
Nitroglycerin Sublingual tablet
-
Cardene
- Nicardipine
- IV emergency HTN
- IR only for angina (tid)
- SR (bid)
-
Plendil
- CCB
- don't crush
Felodipine ER
-
Cleviprex
- CCB
- HTN emergency
- Don't if egg allergy
- Clevidipine
-
-
-
Kombiglyze XR
Saxagliptin/Metformi
-
Rapamune
- for kidney trrasplant
- also used inside the stent
- Sirolimus
-
-
-
Brevibloc
- HTN emergency
- BB Brevibloc
- B1 selective
- Esmolol
-
-
-
Daliresp
- for COPD
- PDE4 inh
- PO, weight loss
- Roflumilast (COPD lasts for ever)
-
Xolair
- allergic asthma
- SC binds to IgE
- Omalizumab (governor o'malley)
-
-
-
Regitine
- HTN emergency
- overdose of TCA,...
- Phentolamine
-
Apresoline
- HTN emergency in pregnancy
- Hydralazine
-
-
-
Multaq
- AF singnificant reduction in morbidity and mortality
- causes liver, heart, renal failure, INR increase
- no vission, thyroid, lung effects like Amiodarone
- Dronedarone (drone drone)
-
Procardia
- CCB
- for Raynaud's
- Nifedipine
-
-
Lopressor
- Metoprolol tartrate
- with food
-
Zaroxolyn
- Thiazide-like
- OK if CrCl<30 (unlike thiazides)
- Metolazone
-
Thalitone
- thiazide-like long acting
- more potent than HCTZ
- Chlorthalidone
-
Valturna
- ARBS+Renin inh
- Valsartan/Aliskiren
- has Tekturna
- Valturna
-
Amturnide
- triple
- Am + turn + ide
- CCB/Renin inh/Thiazide
- Amlopdipine/Aliskiren/HCTZ
- Amturnide has Tekturna
-
Tekamlo
- CCB/renin inh
- Tekamlo has Tekturna
- Tekamlo has Amlodipine
-
Lotrel
- ACEI/CCB
- Benazepril/Amlodipine
-
Lexxel
- CCB/ACEI
- Felodipine/Enalapril
-
Tarka
- CCB/ACEI
- Verapamil/Trandolapril
-
Aldactazide
Spironolactone/HCTZ
-
Hyzaar
- ARB/thiazide
- Losartan/HCTZ
-
Accuretic
- ACE/duretic (thiazide)
- Quinapril/HCTZ
-
Zebeta
- BB
- one of 3 BB used in CHF
- Bisoprolol
-
Ziac
- BB/thiazide
- Ziac has Zebeta
- Ziac has HCTZ
- Ziac has thiazide Bisoprolol/HCTZ
-
-
Lescol
- statin
- Cimetidine and Ranitidine increase Lescol levels up to 70%
- Fluvastatin
-
-
Pravachol
- statin
- No P450: least drug interaction
- Pravastatin
-
Advicor
- statin/niacin
- big risk of myopathy
- know Niacin side effects
- Lovastatin/Niacin
-
Lovaza
- Fish oil
- Omega 3: EPA, DHA
- increases risk of bleeding
- watch with: ASA, Plavix, Coumadin
-
Amaryl
- max 8ml qd
- Glimepiride
- adjust RF
-
Victoza
- Sc pen qd (unlike Byetta bid)
- type 2 only (like Byetta)
- GLP-1 agonist (like Byetta)
- first diarrhea later may constipation. 0.6 then 1.2 then 1.8 (Byetta=constipation=add fiber)
- Weight loss (like Byetta)
- Discard if is not clear
- BBW: thyroid tumor in rodents
- 0.6 then 1.2 then 1.8 to
- Liraglutide
-
Cycloset
- dopa agonist
- DM type 2 only adjunct to diet and exercise
- qd, with food 2h af waking up in the morning
- Bromocriptin
- Parlodel for parkinson is much higher dose
- Parlodel 2.5,5 mg tabs 10-30 mg tid
- Cycloset 0.8 mg tab 1.6-4.8 mg qd
-
Santyl
- DM ulcer ointment
- Collagenase
-
-
Medrol
Methylprednisolone
-
Cesamet
- cannabinoid
- second-line chemo N/V
- CII
- Nabilone (not babilone,lol)
-
Marinol
- cannabinoid
- second-line chemo N/V
- CIII ( maybe cuz it's shorter acting than Cesamet)
- Dronabinol
-
Kayexalate
- Decreases K absorption in the gut.
- for tumor lysis syndrom
- causes constipation, but never give sorbitol.
- Sodium Poly-styrene sulfonate
-
Zolinza
- for lymphoma
- Histone deacetylase inh
- causes QT prolongation
- qd with food
- Vorinostat
-
Nolvadex
- Tamoxifen
- 20mg bid premenopausal
- 10mg bid menopausal
- don't give with Fluoxetine or Paroxetine
- can give with Venlafaxine
- causes endometrial sarcoma
-
Evista
- Raloxifene
- prevention of breast cancer
- not for pre-meno
- used for osteoporosis ( again: not in pre-meno))
-
Herceptin
- monoclonal antibody
- should be:
- HER2+ (human epidermal GF receptor)
- metastatic
- stomach or breast
- should be in combination with Paclitaxel
IV qw 52 weeks - Trastuzumab
-
Xeloda
- metastatic breast cancer resistant to Paclitaxel
- metastatic colorectal cancer first-line
- dosage is cyclical 2w on, 1w off
- prodrug of 5-FU, so is antimetabolite
- Capecitabine if give Tykerb give it with Xeloda (both are po)
-
Taxol
- Paclitaxel
- from 9 existing plant alkaloid in naplex books only this one comes with a brand to know.
- Docetaxel, Paclitaxel (premedicate with Dexa)
- Etoposide, Teniposide (hypotension)
- Irinotecan, Topotecan (diarrhea)
- Vin
cristin, Vinblastin, Vinorelbin ( PN: tingling)
-
-
-
Plaquenil
hydroxychloroquine
-
Arthrotec
- NSAID/Prostaglandin
- diclofenac/Misoprostol
-
Cytotec
- Prostaglandin
- prevents NSAID GI side effects
- Misoprostol
-
Tenex
- alpha 2-adrenergic agonist
- Guanfacine
-
wytensin
- alpha 2-adrenergic agonist
- Guanabenz
-
Catapres
- alpha 2-adrenergic agonist
- has qw patch
- Clonidine
- also for ADHD
-
Besivance
- ophtalmic quinolone
- Besifloxacin
-
Vigamox
- ophtalmic quinolone
- Moxifloxacin
-
Zymar
- ophtalmic quinolone
- Gatifloxacin
-
Moxeza
- ophtalmic quinolone
- Moxifloxacin
-
Iquix
- ophtalmic quinolone
- Levofloxacin
-
Quixin
- ophtalmic quinolone
- Levofloxacin
-
-
Maxaquin
- quinolone
- qd evening to decrease phototoxicity
- Lomefloxacin
-
-
Ciprodex
- otic quinolone
- Ciprofloxacin/Dexamethason
-
Tequin
- quinolone
- Gatifloxacin
- Don't in DM
- QT prolongation don't with Geodon
-
Avelox
- quinolone
- Don't in UTI
- QT prolongation don't with Geodon
- Moxifloxacin
-
Foscavir
- antivirus
- for all forms of CMV
- Foscarnet
-
-
Lyrica
- Pregabalin
- for fibromyalgia, seizure
-
Zarontin
- Ethosuximide
- absence seizure
-
Celontin
- Methusuximide
- refractory absence
-
Topamax
- Topiramate
- seizure: partial, general, LGS
-
Pentasa
- for Crohn's disease
- it's CR, but qid
- Mesalamine
- Urine Yellow brown
-
Asacol
- Mesalamine delayed release tablet
- Urine Yellow brown
-
Edluar
- Sublingual Zolpidem
- should not be taken with water
-
-
Restoril
- Temazepam
- for sleep 15min before bed
-
Prograf
- Inh T cells
- Tacrolimus or FK
- LDL, Glucose, Potassium and BP up
- PTDM= post transplant D
- liver dysfunction decrease dose
- renal dysfunction decrease dose
- Major sub watch with inh ind
- nephrotoxic watch with Amphotericin B
- empty stomach 2h apart from antacids
- hair loss resolves after 6 months
- Hand tremor resolves decrease dose
- Diarrhea and GI upset
-
Protopic
- topical prograf
- Tacrolimus
-
Quetran
- Bile acid sequestrant = Resin (LDL down TG up)
- Cholestyramine
-
Colestid
- Bile acid sequestrant = Resin (LDL down TG up)
- Colestipol
-
Welchol
- Bile acid sequestrant = Resin (LDL down TG up)
- Colesevelam
-
Niacor
Niacin = Nicotinic acid = vit B3 ( LDL, TG down) Myo
-
Nicolar
Niacin = Nicotinic acid = vit B3 ( LDL, TG down) Myo
-
Niaspan
- Niacin = Nicotinic acid = vit B3 ( LDL, TG down) Myo
- it's ER max 2mg/day instead of 4.5mg/day
-
Simcor
- Statin/Niacin
- Simvastatin/Niaspan
- watch for myopathy
-
Advicor
- Statin/Niacin
- Lovastatin/Niacin
- watch for myopathy
-
-
-
-
-
-
Pravachol
- statin
- Pravastatin
- not through P450 ( less interaction with inh ind)
-
-
-
Vytorin
- statin/ chlo abs inh
- Simvastatin/Ezetimibe
-
Lopid
- fibrates = fibric acid derivatives (TG down, LDL up) Myo
- Gemfibrozil
-
Tricor
- fibrates = fibric acid derivatives (TG down, LDL up) Myo
- Tricor affects Triglyceride = TG
- Fenofibrate
-
Trilipix
- fibrates = fibric acid derivatives (TG down, LDL up) Myo
- Trilipix affects Triglyceride = TG
- active metabolite of Fenofibrate
-
Lofibra
- fibrates = fibric acid derivatives (TG down, LDL up) Myo
- Fenofibrate
-
Lipofen
- fibrates = fibric acid derivatives (TG down, LDL up) Myo
- Fenofibrate
-
Antara
- fibrates = fibric acid derivatives (TG down, LDL up) Myo
- micronized cap
- Fenofibrate
-
Triglide
- fibrates = fibric acid derivatives (TG down, LDL up) Myo
- Triglide affects Triglyceride = TG
- Fenofibrate
-
Atromid-S
- fibrates = fibric acid derivatives (TG down, LDL up) Myo
- Clofibrate
-
Lovaza
- (TG down LDL up)
- Omega 3 acid (EPA and DHA)
- more than 18 yo
- risk of bleeding check for bruising
- may freeze the capsules to lower GI effects
-
Zetia
- chlo abs inh ( binds to mediators in intestine)
- Ezetimibe
-
Myleran
- Chemo alkylating agent
- uric acid up (give it with Allopurinol)
- Pulmonary Fibrosis:
- if shortness of breath do chest Xray
- Busulfan
-
Cytoxan
- Chemo alkylating agent
- give Mesna and hydrate (hemorrhagic cystitis)
- Alopecia in 3 weeks
- Cyclophosphamide
-
Ifex
- Chemo alkylating agent
- give Mesna and hydrate (hemorrhagic cystitis)
- Alopecia in 3 weeks
- Ifosfamide
-
BiCNU
- Chemo alkylating agent (NU)
- lipid soluble so for brain tumor
- Carmustine
- Renal, hepa, pulm, BMS
-
CeeNu
- Chemo alkylating agent (Nu)
- lipid soluble so for brain tumor
- Lomustine
- Renal, hepa, pulm, BMS
-
Alkeran
- Chemo alkylating agent (Alkeran)
- BMS, fertility
- Melphalan
-
Zanocar
- Chemo alkylating agent (Zanocar)
- for pancreatic cancer causes DM type 1 (IDDM)
- extravasation, renal
Streptozocin don't confuse with antibiotics -
-
Treanda
- Chemo alkylating agent
- Tumor lysis syndrom (prevent with Allopurinol first few weeks)
- Anaphylaxis
- BMS
- Bendamustine
-
-
Vaprisol
- IV for hyponatremia in SIADH
- antagonizes vasopressin ( ADH ) receptors
- Conivaptan
-
Samsca
- PO for hyponatremia in SIADH
- antagonizes vasopressin ( ADH ) receptors
- Tolvaptan
-
Blenoxane
- Chemo antibiotics
- Pulmonary fibrosis Frequent chest Xray
- skin toxicity (hyper-pigmentation)Red, non uniform spotsBleomycin
-
Xopenex
- Asthma short acting beta 2 agonist
- Nebulizer >6yo and MDI >4yo
- Levalbuterol
-
Qvar
- MDI (only one doesn't need a spacer)
- Beclomethasone
-
Entocort EC
- PO qd capsules for Crohn's
- Budesonide
-
Pulmicort Respulses
- NEB CSI Asthma
- low systemic absorption
- as young as 12 months old
- Budesonide
-
Pulmicort Flexhaler
- DPI CSI Asthma
- only BID has a dose counterBudesonide
-
Pulmicort Turbuhaler
- DPI CSI Asthma
- does not have a dose counter ( unlike Flexhaler)
- Budesonide
-
Zinecard
- Iron chelator
- protects against cardiotoxicity of 2 chemo antibiotics:
- ( Doxorubicin and Daunorubicin )
- Dexra-zox-ane
- Dexrazoxane
-
Doxil
- chemo antibiotic
- Irreversible CHF (due to iron)liposomal form for less toxicity
- Red urine (with all rubicins)extravasation (apply cold)
- pregnancy DDoxorubicin liposomal
-
-
Adriamyacin
- Irreversible CHF (due to iron)
- Red urine (with all rubicins)
- extravasation (apply cold)
- pregnancy D
- Doxorubicin non-liposomal
-
Rhinocort
- nasal CS for allergic rhinitis
- Budesonide
-
Vancenase
- nasal CS
- allergic rhinitis
- polyp prophylaxis
- Beclomethasone
-
Veramyst
- nasal CS allergic rhinitis
- Fluticasone furoate
-
Flonase
- nasal Cs allergic rhinitis
- Fluticasone propionate
-
-
-
Alvesco
- MDI CS asthma
- activates in lung (less oral thrush)
- Ciclesonide
-
Omnaris
- nasal CS allergic rhinitis
- caution with ketoconazole
- Ciclesonide
-
Orapred
- oral prednisolone
- Syrup: 1) in fridge 2)has 2% alcohol
- ODT with or without water, but with food
-
Veripred 20
- oral prednisolone
- viscous syrup
- 20mg/5ml
- in fridge
-
Pediapred
- oral prednisolone
- 5mg/5ml syrup
-
Prelone
- oral prednisolone
- 5% alcoholic syrup
-
Millipred
- oral prednisolone
- 10mg/5ml syrup
-
Flo-pred
prednisolone syrup
-
Asmanex Twisthaler
- DPI CS asthma
- qpm or bid
- Mometasone
-
Nasonex
- nasal CS allergic rhinitis
- Momethasone
-
Volmax
- beta 2 agonist asthma tablet
- it's PO, but refrigeratedAlbuterol
-
VoSpire ER
- beta 2 agonist asthma tablet
- Albuterol
-
Ventolin
- beta 2 agonist asthma MDI
- Albuterol
-
Proventil
- beta 2 agonist asthma MDI
- Albuterol
-
ProAir
- beta 2 agonist asthma MDI
- Albuterol
-
Cromolon
- Mast-Cell stabilizer
- Cromolyn ophthalmic
-
NasalCrom
- Mast-Cell stabilizer
- Cromolyn nasal spray
- 1 spray/nostril
-
Gastrocrom
- Mast-Cell stabilizer
- Cromolyn syrup
- for food allergy and IBD
-
Glynase
- 2nd gen sulfonylurea
- Glyburide Micronized
-
Diabeta
- 2nd gen sulfonylurea
- Glyburide
-
Micronase
- 2nd gen sulfonylurea
- Glyburide
-
Glucotrol
- 2nd gen sulfonylurea
- choice in RF30 min before meal = empty stomach
- Glipizide
-
Riomet
Metformin Syrup 500/5ml
-
Glucovance
- Biguanide/2nd gen sulfonylurea
- Metformine/Glyburide
-
Avandamet
- Biguanide/TZD
- Metformine/Rosiglitazone
-
Actoplus Met
- Biguanide/TZD
- Metformine/Pioglitazone
-
Prandimet
- Biguanide/Meglitinide
- Metformine/Repaglinide
-
-
-
-
-
Kombiglyze
- Biguanide/Gliptin
- Metformin/Saxagliptin
-
-
Avandaryl
- TZD/2nd gen sulfonylurea
- Avandia/Glimepiride
-
-
-
Janumet
- Biguanide/gliptin
- Metformin/sitagliptin
-
-
-
Symlin
- Type 1 & 2 if insulin failed
- always adjunct to insulin
- Amylin analogue
- Pramlintide
-
-
-
Apidra
- rapid insulin has also IV
- Glulisine
-
-
-
Velosulin BR
short insulin
-
-
-
-
Diabinese
- 1st gen sulfonylurea
- Chlorpropamide
- t 1/2 72h
- causes SIADH
-
-
Glucophage
- Biguanide
- Metformin qd, bid
- max 2550 mg/day if XR max 2000
- for PCOS tid
- no hypoglycemia more reliable than all DM drugs
-
-
-
Byetta
- GLP-1 analogue
- type 2 DM Bid
- 6h apart (Ex: 10 am and 2 pm is wrong)
- 1h before meal
- not in CrCl<30
-
Etyol
- premed for cisplatin nephrotoxicity
- causes severe hypotension
- no HTN med 2h before
- Amifostin
-
Paraplatin
- chemo alkylating agent
- less nefrotoxicity than Cisplatin (no need to Amifostine)
- Carboplatin
-
Mustargen
- chemo alkylating agent
- fertility impairment
- pharmacist should not touch it ( if wants to get pregnant)
- Extravasation treat with sodium thiosulfate
- Mechlorethamine
-
Eloxatin
- chemo alkylating agent
- for colorectal cancer
- together with 5FU and Leucovorin
- Oxaliplatin
-
5-FU
- chemo antimeta agent
- with warfarin INR upneed less 5-FU when Leucovorin added
- light sensitive
- Fluorouracil
-
Leucovorin
- folic acid analogue
- given 6-24h after MTX infusion
- protects cells against MTX
- increases efficacy of 5-FU
- Folinic acid
-
Tasigna
- Tyrosine kinase inh (all po)
- for leukemia
- QT
- Nilotinib
-
Tykerb
- Tyrosin kinase inh (all po)
- for breast cancer (5tabs qd on days 1-21)
- together with Xeloda
- Lapatinib
-
Fludara
- anti meta
- irreversible blindness (Neurotoxicity)
- Fludarabine
-
Cytosar
- anti meta
- peripheral neuropathy
- has liposomal for intrathecal given with Dexamethasone
- causes CNS problems
- Vision changes give high dose Dexa eye dropsCytarabine syndrome
- fever, bone pain, chest pain
-
Hexalen
- chemo alkylating agent
- for Ovarian cancer
- peripheral neuropathy
- Fertility impairment
interaction with MAO orthostatic hypotensionAltretamine-
-
Docefrez
- chemo plant alkaloids
- Hypersensitivity premed Dexa 1 day prior
- fluid retention give Lasix
- pulmonary edema give Lasix
- Docetaxel
-
-
Novantrone
- chemo antibiotics only one doesn't end to cin
- Blue urine
- Blue eyes
-
Mitoxantrone
-
Arimedex
- Aromatase inh (1st line in hormonal therapy of breast cancer)
- Anastrozole
-
Femara
- Aromatase inh (1st line in hormonal therapy of breast cancer)
- Letrozole
-
Aromasin
- Aromatase inh (1st line in hormonal therapy of breast cancer)
- Exemestane
-
Halaven
- chemo Microtubule inh
- for breast cancer
- after 2 prior chemo regimens (refractory to anthracycline and taxol)
- Eribulin
-
Ixempra
- Chemo microtubule inh
- structure epothilone analogue
- for breast cancer if refractory to taxol and anthracycline therapy
- Ixabepilone
- premed wit H1 & H2 blockers 1h before
- avoid inducers or inhibitors so no Cimetidine
-
-
Mithracin
- chemo antibiotic
- Electrolyte imbalance ( Ca, K, PO4 down)
- used also for Hypercalcemia
- Plicamycin
-
Cosmegen
- chemo antibiotic
- Extravasation
- contra with active chickenpox, shingles
- Dactinomycin
-
VP-16
- chemo plant alkaloid
- caps in fridge
- if rapid infusion hypotensionEtoposide
-
Vumon
- chemo plant alkaloid
- if rapid infusion hypotension Teniposide
-
Camptosar
- chemo plant alkaloid
- life-threatening diarrea
- early give Atropin then Loperimide with no max
- Irinotecan
-
Hycamptin
- chemo plant alkaloid
- life-threatening diarrea
- early give Atropin then Loperimide with no max Irinotecan
- Topotecan
-
Gleevec
- Tyrosin kinase inh (all po)
- fluid retension so monitor weight gain
- Strong inh watch with warfarin
- Imatinib
-
Tarceva
- Tyrosin kinase inh (all po)
- for lung and pancreatic cancer
- discontinue if lung disease occurs
- empty stomach
- Erlotinib
-
Faslodex
- chemo estrogen antagonist
- metastatic breast cancer
- after other antiestrogen therapy
- slow IM each buttock on days 1,15,29 then qm
- if hepatic impairment give half the dose.
- thrombocytopenia so risk of bleedingFulvestrant
-
Megace
- for breast or endometrial cancer po
- it's progesteron, but causes thromboembolism!
- Megestrol
-
Proscar
- 5 alpha reductase inh T to DHT
- prevention of prostate cancer
- Finasteride 5mg
-
Avodart
- 5 alpha reductase inh T to DHT
- prevention of prostate cancer
- Dutasteride
-
Xegeva
- RANK inh (it's IgG binds to RANK) inhibits osteoclast
- for bone metastases (prevents complications)
- SC 120 mg qm
- Denosumab
-
Prolia
- RANK inh (it's IgG binds to RANK) inhibits osteoclast
- for osteoporosis ( post menopausal)
- SC 60 q6m
- Denosumab
-
Zoladex
- LH-RH GnRH analogues
- SC upper abdomen
- for prostate cancer
- for endometriosis
- for breast cancer (pre-menopausal) hormone positive
- causes tumor flare premed with anti-androgens
- Goserelin
-
Lupron
- LH-RH GnRH analogues
- IM
- for prostate cancer
- for endometriosis
- for breast cancer (pre-menopausal) hormone positive
- causes tumor flare premed with anti-androgens
- Leuprolide
-
Trelstar
- LH-RH GnRH analogues
- IM
- for prostate cancerfor endometrosis
- for breast cancer (pre-menopausal) hormone positive
- causes tumor flare premed with anti-androgens
- Triptorelin
-
Eligard
- LH-RH GnRH analogues
- it's depo SC
- for prostate cancer
- for endometrosis
- for breast cancer (pre-menopausal) hormone positive
- causes tumor flare premed with anti-androgens
- Leuprolide
-
Viadur
- LH-RH GnRH analogues
- implant qy
- for prostate cancer
- for endometrosis
- for breast cancer (pre-menopausal) hormone positive
- causes tumor flare premed with anti-androgens
- Leuprolide
-
Plenaxis
- GnRH antagonist
- IM
- advance prostate cancer (symptomatic)
- if not condidate for LH-RH GnRH analogues
- it's for palliative treatment
- doesn't cause tumor flare
- suppresses LH and FSH
- Abarelix
-
Eulixin
- anti-androgens (block production) (all po)
- only with LH-RH GnRH analogues (prevent tumor flare)
- has the worst diarrhea in the group
- fatal liver disfunctionflutamide
-
Casodex
- anti-androgens (block production) (all po)
- only with LH-RH GnRH analogues (prevent tumor flare)
- diarrhea
- warfarin up (protein binding)
- Biclutamide
-
Nilandron
- anti-androgens (block production) (all po)
- only with LH-RH GnRH analogues (prevent tumor flare)
- Constipation
- disulfiram
- dark vision problem
- Nilutamide
-
Valstar
- chemo antibiotics
- for bladder cancer
- urine Red
- causes irritable bladder syndrom
- Valrubicin
-
Purinethol
- chemo anti meta
- causes hyperuricemia give Allopurinol
- Bactrim and Allopurinol increase the level of Purinethol
- Mercaptopurine
-
6-MP
- chemo anti meta
- causes hyperuricemia give Allopurinol
- Bactrim and Allopurinol increase the level of Purinethol
- Mercaptopurine
-
Matulane
- chemo alkylating agent
- MAOI (Matulane)
- fatal HTN if given for example with avocados
tremor and convulsion in kids - disulfiram
-
Procarbazine
-
G-CSF
- reduces chemo febrile neutropenia
- SC or IV
- bone painFilgrastim
-
Neulesta
- reduces chemo febrile neutropenia
- SC 6mg once each chemo cycle
- bone pain
- Pegfilgrastim
-
Neupogen
- reduces chemo febrile neutropenia
- SC or IV
- bone pain
- Filgrastim
-
Neumega
- IL-11 increases platelets in chemo
- SC qd 6-24h after chemountil platelets > 50000
- (normal is 150000-450000)
- fluid retention
- Oprelvekin
-
-
-
-
Emend
- NK1 antagonist (blocks substance P)
- chemo antiemetic
- should be used together with 5-HT3 Sr antagonist and stroids
- it's inducer (COC and INR down)Aprepitan (po)
-
Emend IV
- NK1 antagonist (blocks substance P)
- chemo antiemetic
- should be used together with 5-HT3 Sr antagonist & stroids
- it's inducer (COC and INR down)
- 115 mg on day 1 of chemo
- Fosaprepitant converts to Aprepitant
-
Kytril
- 5-HT3 inh (1st line for chemo N/V) all have IV/PO
- Granisetron
-
Anzemet
- 5-HT3 inh (1st line for chemo N/V) all have IV/PO
- Dolasetron
-
Sancuso
- 5-HT3 inh (1st line for chemo N/V)
- patch1-2 days before chemoeach patch can be worn for 7 days, but avoid sun (suncuso)Granisetron
-
Aloxi
- 5-HT3 inh (1st line for chemo N/V) all have IV/PO
- 0.5 mg one hour before chemo
- longer (1-2 days) Aloxi Palonosetron
- Palonosetron
-
Zofran
- 5-HT3 inh (1st line for chemo N/V) all have IV/PO
- only one with IMOndansetron
-
-
Fosamax
- Bisphosphonates (osteoclast inh)
- prevention and treatment of osteoporosis
- first thing in the morning after overnight fast.
- Alendronate PO
-
Actonel
- Bisphosphonates (osteoclast inh)
- prevention and treatment of osteoporosis
- first thing in the morning after overnight fast.
- Risedronate PO
-
Atlevia
- Bisphosphonates (osteoclast inh)
- prevention and treatment of osteoporosis
- the only one can take after breakfastbecause it's enteric coated (delayed-release)
- 35mg qw
- Risedronate
-
Boniva
- Bisphosphonates (osteoclast inh)
- prevention and treatment of osteoporosis
- first thing in the morning after overnight fast.
- upright 60min for bonuva as oppose to 30min for others
- the only one has both PO, IV
- causes HTN, constipaton, HA
- Ibandronate
-
Reclast
- Bisphosphonates (osteoclast inh)
- prevention and treatment of osteoporosis
- only IV: 5mg qy 15 min infusion
- avoid if CrCl<30
- Fever
- Zolindronic acid
-
Zometa
- Bisphosphonates (osteoclast inh)
- not for osteoporosis
- for hypercalcemia of malignancy
- for multiple myeloma (bone cancer)
- only IV: 4mg qm (every 3-4 week) 15 min infusion
- avoid if CrCl<30
- FeverZolindronic acid
-
Aredia
- Bisphosphonates (osteoclast inh)
- not for osteoporosis
- for hypercalcemia of malignancy
- for Paget's
- for bone disease
- Only IV: infuse over 2-24 h to decrease renal toxicity
- Pamidronate
-
Didronel
- Bisphosphonates (osteoclast inh)
- for Paget's
- Etidronate PO
-
Peridex
- don't eat for 2-3 h after (may cause staining)
- brush and floss then rinse 30 sec with 15ml undiluted
- prevention of ONJ (osteonecrosis of the jaw) with Bisphosphonate and prolia
- Chlorhexidine
-
Enbrel
- TNF blocker
- refractory RA
- SC 50mg qw thight
- Etanercept
-
Remicade
- TNF blocker
- refractory RA, Crohn's, UC, psoriasis,
- IV
- risk of CHF
- Infliximab
-
Humira
- TNF blocker
- for RA
- Adalimumab
-
Simponi
- TNF blocker
- for RA
- Golimumab
-
Cimzia
- TNF blocker
- for RA
- Certolizumab
-
Kineret
- IL1 blocker
- RA 100mg SC qd
- Anakinara
-
Arava
- Pyrimidine inh (inh dihydroorotate dehy)
- RA po qd
- Leflunomide
-
Azulfidine
- Folate syn inh
- UC, RA
- po after meal (like ASA)
- Sulfasalazine
-
Orencia
- inh T cell activation
- RA IV qm
- watch COPD
- Abatacept
-
Rituxan
- binds to CD20 on Bcells
- RA and Lymphoma (non-hodgkins)
- RA IV 1g q2w
- Rituximab
-
Actemra
- IL6 inh
- RA IV qm
- Tocilizumab
-
Aggrenox
- ASA + Dipyridamole
- adjunct to Warfarin or ASA
- 1 cap bid
-
Persantine
- riversible platelet agg inh
- Dypiridamole
-
Mycostatin
vaginal Nystatin
-
Provera
- Medroxyprogesterone
- for HRT, Amenorrhea, DUB (disfunctional uterine bleeding)
-
Bidil
- Hydralazine + isosorbide dinitrate
- HF adjunct to standard therapy in black pt
-
Lysteda
- for menorrhagia po
- inh plasminogen
- Tranexamic acid
-
-
Danocrine
- Danazol
- Endometriosis
- supresses LH and FSH
-
-
RU-486
- Mifepristone
- preg termination
-
-
-
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