-
Retrovir®
NRTI (AZT, zidovudine)
Dose:
- S/E: Bone marrow suppression, granulocytopenia, anemia, nausea, vomiting, dizziness, myalgias, headaches, fatigue.
- Mitochondial toxicity, lipoatrophy
DI: Zerit® (D4T, stavudine)
-
Videx®
NRTI (ddI, didanosine)
- Dose:
- Wt >60kg 200mg BID, 400mg EC Daily
- Wt <60 kg 125mg BID, 250mg EC Daily
- S/E: Pancreatitis, peripheral neuropathy, leukopenia.
- Mitochondrial toxicity, lipoatrophy
DI: Viread® (tenofovir), Zerit® (D4T, stavudine)
-
Zerit®
NRTI (D4T, stavudine)
- Dose:
- Wt >60kg 40mg BID
- Wt<60kg 30mg BID
- Dose to renal function
- S/E: Peripheral neuropathy, pancreatitis, increase LFTs.
- Mitochondrial toxicity, lipoatrophy
DI: Retrovir® (AZT, zidovudine), Videx® (ddI, didanosine)
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