-
Cimetidine
- H2 Antagonist
- Famotidine>Ranitidine=Nizatidine>Cimetidine
- Usage: GUD, PUD, GERD, Zollinger-Ellison Syndrome, Dyspepsia
-
Omeprazole
- PPI
- Esomeprazole, Lansoprazoel, Rabeprazole (reversible), Pantoprazol
- Prodrug, acid-labile, CYP2C19 inhibition, P-glycoprotein inhibition (Statin-prob), Atazanavir, azole absorp inhibition
- Usage: GUD, PUD, GERD, Zollinger-Ellison syndrome
-
Antacids
- Mg(OH)2, Al(OH)3, CaCo3, NaHCO3
- Usage: PUD
-
Pirenzapine
- M receptor Antagonist
- Atropine
- Usage: PUD
-
Sucralfate
- Carafate
- Sulfated sucrose and Al(OH)3
- Inhibits absorption of other drugs (Take 2 hrs before and after taking other drugs)
- Usage: PUD
-
Misoprostol
- Cytotec
- PGE1 analog
- Pregnancy X
- Usage: NASID-induced ulcers
-
Bismuth subsalicylate
- H. pylori
- antidiarrheal too by inhibiting intestinal secretions
-
Methylcellulose
- Citrucel
- Bulk-Forming Laxative (Dietary fiber)
- Antidiarrhea
- Drink a lot of water
- GroupIII
-
Psyllium
- Metamucil
- Bulk-Forming Laxative (Dietary fiber)
- Antidiarrhea
- Drink a lot of water
- GroupIII
-
Polycarbophil
- FiberCon
- Bulk-Forming Laxative (Dietary fiber)
- Antidiarrhea
- Drink a lot of water
- GroupIII
-
Docusate Sodium(Calcium)
- Surfactant Laxatives
- lowering surface tension-increase penetration of water into the feces
- GroupIII
-
Bisacodyl
- Correctol, Dolcolax
- Stimulant Laxatives (Secretory, Irritant)
- Stimulate intestinal motility
- GroupII
-
Senna
- Senokot, Ex-Lax
- Stimulant Laxatives (Secretory, Irritant)
- Stimulate intestinal motility
- GroupII
-
Castor Oil
- Stimulant Laxatives (Secretory, Irritant)
- Stimulate intestinal motility
- GroupI
-
Magnesium hydroxide
- Phillips' Milk of Magnesia
- Osmotic Laxatives(Saline)
- Attract water in the lumen
- GroupI or II
-
Sodium phosphate
- Fleet Phospho-Soda
- Osmotic Laxatives(Saline)
- Attract water in the lumen
- GroupI or II
-
Polyethylene Glycol
- MiraLax
- Osmotic Laxatives(Saline)
- Attract water in the lumen
- GroupI or II
-
Lubiprostone
- Amitiza
- Mis. Laxatives
- CIC-2 chloride channel opener
- Pregnancy C
- Group III
-
Diphenoxylate
- Opioids (mu and delta)
- Decrease GI motility, secretion, Increase absorption of fluid and salt
- Mix with Atropine to prevent abuse potential
-
Loperamide
- Imodium
- Opioids (mu and delta)
- Decrease GI motility, secretion, Increase absorption of fluid and salt
-
Atropine
- Anticholinergic antispasmodics
- relieve cramping of diarrhea
-
Ondansetron
- Zofran
- 5HT3 antagonists
- Block in the CTZ and STN
- Usage: CINV, radiation, postoperation (Antiemetic)
-
Dexamethasone
- Decadron
- Glucocorticoids
- Usage: CINV (Antiemetic)
-
Aprepitant
- Emend
- NK1 antagonists
- Block in the STN
- Usage: CINV (Antiemetic)
-
Prochlorperzine
- Compazine
- D2 antagonists
- Blocks in the CTZ and STN
- Usage: Usage: CINV, postoperation, General (Antiemetic)
-
Dronabinol
- Marinol
- Cannabinoids agonist
- Usage: CINV (Antiemetic)
-
Scopolamine
- Transderm Scop
- Anticholinergics
- Block M1
- Usage: Motion Sickness (Antiemetic)
-
Dimenhydrinate
- Dramamine
- Block H1 and M1
- Antihistamines
- Usage: Motion Sickness (Antiemetic)
-
Graniseteron, Dolasetron
- Kytril, Anzemet
- 1st Gen 5HT3 receptor antagonists (Antiemetic)
-
Palonosetron
- Aloxi
- 2nd Gen 5HT3 receptor antagonists (Antiemetic)
-
Meclizine
- Antivert
- H1 receptor antagonists
- Usage: Motion Sickness (Antiemetic)
-
Promethazine
- Phenergan
- H1 receptor antagonist with sig. antimuscarinic activity
- Usage: Nausea and Vomiting for Postop(Antiemetic)
-
Alosetron
- 5HT3 Antagonist
- Usage: IBS-D
-
Lubiprostone
- CIC-2 activator
- Usage: IBS-C
-
-
Cisapride
- 5HT4 agonist
- Usage: GERD, gastroparesis, severe chronic constipation
- Last resort
-
Sulfasalazine
- 5-Aminosalicylates
- Usage: Ulcerative colitis, Crohn's disease
-
Mesalamine
- 5-Aminosalicylates
- Usage: Ulcerative colitis, Crohn's disease
-
Predinisone
- Glucocorticoid
- Usage: ulcerative colitis, Crohn's disease (reduce remission)
-
Infliximab
- Anti-TNF-a Monoclonal antibody
- Usage: Crohn's disease, ulcerative colitis
-
Metoclopramide
- D2 antagonist
- Usage: CINV, postop NV, diabetic gastroparesis, GERD
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