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Spinal Cord Location and Structure
- •Provides a two-way conduction pathway to and from the brain
- •Begins at the foramen magnum
- •Ends as conus medullaris at L1 or L2 vertebral level in most adults
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Filum Terminale
- -fibrous extension from conus medullaris that anchors the spinal cord to the coccyx
- •31pairs of spinal nerves (8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccyx)
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Features of the spinal cord
•The cauda equina is a collection of spinal nerves at the inferior end of the spinal cord, below the conus medularis
•Cervical and lumbar enlargements the nerves serving the upper and lower limbs emerge here
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The Bony Skeleton
- •The spinal cord sits in the vertebral canal
- •The spinal nerves exit from the intervertebral foramen with the exception of C1spinal nerve which exits between the skull and the C1 vertebra
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Spinal Cord Anatomy
- •Internal gray matter is mostly cell bodies
- •Gray matter surrounds the central canal
- •Central canal is filled with cerebrospinal fluid
- •Exterior white mater
- •conduction tracts
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Gray Matter
- Dorsal horns (pointed)
- •interneurons that receive somatic and visceral sensory input
- Ventral horns (rounded)
- •somatic motor neurons whose axons exit the cord via ventral roots
- Lateral horns (only in thoracic and lumbar regions)
- •Visceral output via sympathetic neurons visceral motor
- Dorsal root (spinal) ganglia•contain cell bodies of sensory neurons one for each spinal level
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White Matter (Tracts)
- •Consists mostly of ascending (sensory) and descending (motor) tracts
- •Transverse tracts (commissural fibers) cross from one side to the other
- Tracts are located in three white columns
- 1.dorsal (posterior)
- 2.lateral
- 3.ventral (anterior)
•Each spinal tract is composed of axons with similar functions
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Spinal Cord Anatomy
•Spinal nerves leave at the level of each vertebrae
•Spinal nerve consists of:
- Dorsal root
- •Axons carry somatic and visceral sensoryinformation
- •Associated with the dorsal root ganglionat each spinal level of the cord
- •Ganglia are collections of cell bodies ofunipolar neurons outside the central nervous system
- Ventral root
- •Axons that carry motor output
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Pathway Generalizations
- •Pathways decussate (cross over) 10% go straight down and cross at the spinal cord
- •Most consist of two or three neurons (a relay)
- •Pathways are paired symmetrically (one on each side of the spinal cord or brain)
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Descending Pathways and Tracts
•Involve two neurons:
- 1.Upper motor neurons (brain)
- •Pyramidal cells in primary motor cortex, can't recieve info
- 2.Lower motor neurons (spinal cord)
- •Ventral horn motor neurons
- •Innervate skeletal muscles, can't carry info to muscles
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The Pyramidal System
- •Impulses from pyramidal neurons in the precentral gyri pass through the pyramidal (also called corticospinal) tracts then to appropriate muscle
- •Axons synapse with ventral horn motor neurons
- •The pyramidal system controls fast and fine (skilled) movements
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Peripheral Nervous System (PNS) Nerve Structure
- Endoneurium (inside)
- • surrounds each fiber
- Perineurium (around)
- •Binds groups of fibers into fascicles
- Epineurium (outside)
- •Binds fascicles together
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PNS:Classification of Nerves
- Mixed nerves
- •Both sensory and motor fibers
- Sensory(afferent) nerves (dorsal)
- •Carry impulses toward the CNS
- Motor (efferent) nerves (ventral)
- •Carryimpulses away from the CNS
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PNS Spinal Nerves
- •31 pairs of spinal nerves
- •Formed by the combination of the ventral and dorsal roots of the spinal cord
- •Named for the region from which they arise
- •C8 comes out between C7/T1, T1 comes out between T1/T2 (named for the vertebrae above it)
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PNS: Anatomy of Spinal Nerves
•Spinal nerves divide soon after leaving the spinal cord into a dorsal ramus and a ventral ramus
- Ramus•branch of a spinal nerve
- •contains both motor and sensory fibers
- Dorsal ramus
- •serve the skin and muscles of the posterior trunk
- (feed paravertebral region of muscles)
- Ventral ramus
- •form a complex of networks (plexus) for the anterior
- (thoracic region follows the intercostal space)
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PNS: Spinal Nerve Plexuses
- Plexus
- •networks of nerves serving motor andsensory needs of the limbs
- •Form from ventral rami of spinal nerves in the cervical, lumbar, and sacral regions
- Four plexuses:
- •Cervical
- •Brachial
- •Lumbar
- •Sacral
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Cervical Plexus
- •Originates from ventral rami of C1 – C5
- •Serves anterior neck muscles known as the strap muscles
- Important nerve:•Phrenic nerve roots from C3,4,5 supplying the diaphragm
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Brachial Plexus
•Originates from ventral rami in C5 – C8 andT1( posterior to clavicle and anterior to the 1st rib)
- Important nerves:
- •Radial nerve
- •Terminal branch of radial nerve called the axillary nerve
- •Median nerve
- •Musculocutaneous nerve
- •Ulnar nerve
- Areas served
: - shoulder, arm, forearm, and hand
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Lumbar Plexus
- •Originates from ventral rami in L1 through L4
- Important nerves
:- •Femoral
- •Obturator
- •L2, L3, L4
- Areas served
:- •Lower abdomen L1 sensory
- •Anterior and medial thighs L2, L3, L4
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Sacral Plexus (lumbosacral plexus)
•Originates from ventral rami in L4-L5 and S1–S4
- Important nerves:
- •Sciatic (huge, a thumb width)•Superior and inferior gluteal
- Areas served:
- •Lower trunk and posterior thigh
- •Lateral and posterior leg and foot
- •Gluteal muscles of hip area
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PNS: Cranial Nerves
- •Twelv epairs of nerves that mostly serve the head and neck
- •Only the pair of vagus nerves extend to thoracic and abdominal cavities
- •Most are mixed nerves, but three are sensory only (CN I, II and VIII)
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PNS: Cranial Nerves Device
- •I – Olfactory nerve, smell
- •II – Optic nerve, sight
- •III – Oculomotor nerve
- •IV – Trochlear nerve
- •V – Trigeminal nerve
- •VI – Abducens nerve
- •VII – Facial nerve
- •VIII – Vestibulocochlear nerve, hearing
- •IX – Glossopharyngeal nerve
- •X – Vagus nerve(wanders from head to transverse colon)
- •XI – Accessory nerve
- •XII – Hypoglossal nerve
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What is a Dermatone?
A patch of skin supplied by one spinal nerve segment.
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PNS: Cranial Nerves I-IV
- •I Olfactory nerve: special sensory for smell
- •II Optic nerve: special sensory for vision
- •III Oculomotor nerve: motor fibers to most eye muscles(2 exceptions) rasies the eye lid
- •IV Trochlear nerve: motor fiber to the superior oblique eye muscle
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PNS: Cranial Nerves V-VIII
- •V Trigeminal nerve: all 3 divisions are sensory for the face; the 3rd division also has motor fibers to the muscles for chewing
- •VI Abducens nerve: motor fibers to lateral rectuseye muscles
- •VII Facial nerve: Special sensory for taste; motor fibers to the face; visceral motor fibres to glands of face except for parotidgland
- •VIII Vestibulocochlear nerve: sensory for balance and hearing
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PNS: Cranial Nerves IX-XII
- •IX Glossopharyngeal nerve: sensory for taste; motor fibers to the one muscle of the pharynx; visceral motor fibres to parotid gland
- •X Vagus nerves: Visceral sensory and motor fibers for pharynx, larynx, and viscera
- •XI Accessory nerve: motor fibers totrapezius and sternocleidomastoidmuscles
- •XII Hypoglossal nerve: motor fibers to tongue
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