Ophthalmic Pharma

  1. Symp Agonist Drugs
    • Adrenaline
    • Dipivefrine
    • Phenylephrine
    • Apraclonidine
  2. Phenylephrine is Contra Indicated in
    Narrow Angle Glaucoma
  3. Adrenaline SE
    • Reactive Hyperaemia
    • Local Irritation
    • Allergy
    • Blurring of Vision
    • Conjunctiva Fibrosis
    • Cystoid Macular oedema in Aphakia
    • Systemic SE- HT, Headaches
  4. Symp Antagonists
    • B blockers
    • Guanethidine
    • Thymoxamine
  5. Non Selective B Blockers
    • Simalol
    • Timalol
    • Trigger SE in Asthma and Cardioresp diseases
  6. Selective B Blocker
    • Bitaxolol
    • Safe in asthma
  7. B Blocker SE
    • Bronchospasm
    • Cardiac Arrhythmia- esp Bradycardi
    • Depression- Rare
    • Local SE eg Allergy- V Rare
  8. Parasymp Agonisits
    • Pilocarpine
    • Carbachol
    • Acetylcholine
    • Physostigmine
    • Edrophonium
    • Phospholine Iodide
  9. Action of Pilocarpine
    • Causes Trabecular Meshwork to Open
    • V useful in Narrow Angle Glaucoma
    • Causes intense Myosis- exacerbates cataract symp
  10. Pilocarpine SE
    • Dec Visual Acquity - esp in Cataract
    • Allergy
    • Iris Cysts
    • Retinal Detachment
    • Transient Headache
    • Systemic SE:
    • - Sweating
    • - Nauesea and Vomiting
    • - Bradycardia
    • - Diarrhea
  11. Acetylcholine and carbacol Use
    • Used after surgeries with big eye incision.
    • Injected into anterior chamber
    • Constricted pupil v efficiently
    • Dec Chance of Iris Prolapse
  12. Physostigmine and Phospholine Iodide Use
    Chilren with squints
  13. Parasymp Antagonists
    • Atropine
    • Homatropine
    • Cyclopentolate
    • Tropicamide
  14. Cyclopentolate Action
    • Pupil Dilator- Onset- 30 min, Duration- 24hrs
    • Cyclopelgic- Relax Ciliary Body- Dec Pain
    • Used for Cataract surgery
    • Mild dilator and Cycloplegic agent allows pupil to move and not stick into constricted/ dilated position- useful in Uveitis
  15. Tropicamide Action
    • Dilation of Pupil
    • No cycloplegia - no loss of accomodation
    • Short Acting- 3-6 hrs
    • Out Pt Setting
  16. Atropine SE
    • Allergy
    • Fever in Children (Malignant Hyperthermia)
    • Cycloplegic- loss of accomodation and blurring
    • Systemic SE:
    • - Tachycardia
    • -Facial Flush
    • -Tremor
    • -Dry Mouth
  17. Use of Topical Steroids
    • Any inflammation in eye EXCEPT Herpes Simplex Keratitis
    • Uveitis
    • Scleritis
    • Keratitis
    • Post Op Inflam
  18. Acetazolamide- Type of drug and trade name
    • Carbonic Angydrase Inhibitor
    • Diamox
  19. Acetazolamide Uses
    • Dec IOP
    • Dec ICP
    • Mountain Sickness
    • Macular Oedema
    • Retinitis Pigmentosa
    • Glaucoma
  20. Acetaxolamide SE if used long term eg in Glaucoma
    • Parasesthesia
    • Malaise
    • Nausea
    • Loss of appetite
    • Depression
    • Hypokalaemia- give K supplements
    • Renal Stones
    • Steven Johnson's
  21. Systemic Corticosteroid SE
    Cataracts
  22. Systemic Amiodarone SE
    Corneal Deposits- Coneal Verticellosta
  23. Systemic Cholorquine SE
    Maculopathy
  24. Systemic Ethambutol SE
    Optic Neurits
  25. Systemic Chloramphenicol SE
    Disc Oedema
  26. Systemic Tetracycline
    • Papilloedema
    • Bilateral optic disc swelling but no inc IOP
  27. Systemic Steptomycin and Carbamezapine SE
    Nystagmus
  28. Systemic Metoclopramide SE
    Oculogyric Crisis
Author
Rosie435
ID
131415
Card Set
Ophthalmic Pharma
Description
Ophthalmic Pharma
Updated