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Pharmacology 3
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The functions for the ANS system is regulating:
Blood Pressure
Heart Rate
GI Tract
Salivary Gland Secretions
Bronchial Smooth Muscle
The ANS relies on specific
neutot
and a variety of
rceptor
to initiate functional responses in target tissues
Neurotransmitters
Receptors
ANS drugs are used in Dentistry as:
Vasoconstrictors
Used to increase/decrease saliva flow
PANS
Parasympathetic
SANS
Sympathetic
Each division of the ANS has:
1.Afferent (sensory) fibers
2. Efferent (motor) fibers
3. Central Intergrating Areas
PANS is concerned with?
Conservation of body process
ex
: digestion & intestinal tract
Constricted pupils
SANS is designed for?
Emergencies
[
fight-or-flight
]
ex
: dilated pupils
Neurotransmitters
Are released because of nerve action potential or pharmacologic agents
Interact with
receptors
and produce an effect
Drugs can modify the ANS by altering
blank
of neurotransmitters
Synthesis
Storage
Release
Receptor
Disposition
A drug that stimulates the PANS is called:
P
+
Cholinergic
Parasympathomimetic
A drug that blocks the PANS is called:
P
-
Anticholinergic
Parasympatholytic
Cholinergic blockers
A drug that stimulates the SANS is called:
S
+
Sympathomimetic
Adrenergic
A drug that blocks the SANS is called:
S
-
Adrenergic Blockers
Sympathetic Blockers
Sympatholytic
Cholinergic Agents
Parasympathomimetic
Direct
: acts on receptor
Indirect
: causes release of neurotransmitter
Adverse Effects of Cholinergic Agents:
S
alivation
L
acrimation
U
rination
D
efecation
Mixing more than one group possessing anticholinergic effects can lead to
toxicu
Toxicity
Beta 1
Stimulation will increase heart rate and force of contraction
Beta 2
Stimulation will relax smooth muscle in airways
[
treats bronchodilation
]
Beta Blockers
Block the Beta 1 receptor to reduce heart rate and BP
Beta 2 Agonists
Stimulates Beta 2 to cause bronchodilation
Author
svisperas
ID
129851
Card Set
Pharmacology 3
Description
Week 3
Updated
2012-01-23T04:01:12Z
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