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alpha MN
- innervate EXTRAfusal muscle fibers
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gamma MN
- - innervate INTRAfusal muscle fibers
- - regulates sensitivity of muscle spindle so sensitivity can be maintained throughout contraction
- - under supraspinal control
- - can regulate muscle tone
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1a
- sensory axons in muscle spindles of proprioception
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1b
- sensory axons of proprioception in golgi tendon organs
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myotactic reflex
- -1a sensory neuron synapses directly on alpha MN in spinal cord (monosynaptic)
- -accompanied by reciprocal inhibition of anatgonist muscles (poly synaptic)
- -aka deep tendon reflex, stretch reflex
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golgi tendon reflex
- -1b sensory neuron synapses on interneuron in spinal cord which INHIBITS alpha MN
- - responds to muscle tension to prevent tears by inhibition of alpha MN
- - inhibitors polysynaptic
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withdrawl reflex
- -polysynaptic, excitatory tht involves many levels of the spinal cord
- -C or 1 delta axonal input
- - withdrawl response from nociceptive stimuli
- - crossed extensor reflex often accompanies
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crossed extensor reflex
- - often in combo with withdrawl reflex
- - complex, polysynaptic
- - activation of extensor muscles and inhibition of flexors on opposite side of nociceptive stimuli
- - upper and lower limbs exhibit
- - "step on a nail, nail leg withdrawls, non-nail leg stiffens to take on extra load
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axon reflex
- - NO SYNAPSES, TRAVELS AWAY FROM SPINAL CORD (antidromically)
- - thought to spread vasodilation
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clonus
- -series of involuntary muscular contractions due to sudden stratching
- - result of UMN lesions
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thalamus blood supply
-PCA and posterior choroidal branches from the PCA
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UMN's of the corticobulbar tracts innervate bilaterally with the exception of what
- -CN VII (ventral cell group)- supply muscles of the lower quadrant of the face
- -CNXII- genioglossus muscle
- -CN XI- trapezius and SCM
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medial reticulaspinal tract
- - origin-pons
- -decussation- none
- -termination- lamina 8
- - function- action on gamma MN, increase muscle tone and enhance antigravity reflexes
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rubrospinal tract
- -origin: red nucleus of midbrain
- - decussation: midbrain
- - terminate- lamina V-VIII (cervical cord)
- - innervate flexor muscles (functionally parallel to CST)
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Lateral vestibulospinal tract
- origin: LV nucleus of medulla
- decussation: none
- terminate: lamina VII and VIII
- function: alpha and gamma MN that innervate extensor muscles, maintain posture, modulated by Cb
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occlusion of PICA/vertebral artery affects
- - inferior Cb peduncle
- - ST tract
- - sympathestic fibers
- - nucleus ambiguous
- -nucleus solitarius
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occlusion of AICA affects
- - middle Cb peduncle
- -vestibular nuclei
- -spinal V nucleus and tract
- -ST tract
- - descending sympathetic fibers
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superior Cb artery occlusion affects
- superior Cb peduncle and Cb
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CN at risk for damage in infection of carotid sinus
-CN III, IV and V (V1, V2, V3)
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ACA and MCA occlusion
- - proximal arm and leg weakness
- - often include trunk and proximal limbs
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MCA and PCA occlusion
problems with visual processing
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spinocerebellar overview
- - afferents from muscle spindles/joint receptors
- -enter ant. Cb as mossy fibers via peduncles
- -corollary motor fibers also enter from rubrospinal tract
- -DCN computes and decides
- - globoform and emboliform nuclei send modify signal to reticulospinal and rubospinal tracts for motor output (signal does not enter cortex)
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pontocerebellar overview
- -afferent sensory from cortex(world) and corollary motor (intention) also enters posterior lobe of Cb
- - DCN computes
- - dentate sends info to VL to cortex to modulate corticospinal= precesion and sequence
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vestibuloCb overview
- -afferent from vestibular apparatus enter flocculonodular lobe
- - DCN computes
- - Fastigial nucleus sends modulation to change position of eye and trunk in response to head movement
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strabismus
- medial deviation of an eye
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visual p/w
-optic nerve-tract-chiasm-LGN-redaition- visual cortex (17) in occipital lobe
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fusiform gyrus
- - part of the medial temporo occipital lobe associated with face recognition
- - damage results in posopagnosia- inability to recognize faces
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Extrastriate area of the association visual cortex
- M ganglion in the parietal lobe= 'where p/w'
- P ganglion in the temporal lobe= 'what p/w'
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circadian rhythm p/w
-retinol ganglion cells- SCN- paraventricular nucleus- spinal cord- sympathetic trunk- superior cervical ganglion- pineal gland
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N1 sleep
- -alpha (eyes closed) to theta (N1)
- - loss of most muscle tone and awareness of external environment
- - myoclonus and hypnogonic hallucinations
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N2 sleep
- - K-complexes and sleep spindles
- -occupies most (45-55%) of total sleep in adults
- - total loss of awareness of external environment
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N3
- - delta wave (min 20%)
- - may have night terrors, bed wetting, sleep walking and sleep talking
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REM
- - Beta wave sleep (beta waves also seen during awake)
- - muscular atonia and dreaming
- -20-25% total sleep
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Argyll robertson pupil
- - small irregular pupil that does not constrict to light, but does for accomodation
- - commonly caused by neurosyphilis
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marcus gunn pupil
- light in affected eye will not cause constriction in either eye
- - afferent CN III disfunction
- - light in unaffected eye will cause constriction in both
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Adies pupil
- - aka "tonic pupil"
- - caused by degeneration of the ciliary ggl and postganglionic parasympathetic fibers
- - light reaction shows prolonged and sluggish constriction
- - near reaction occurs, but pupil remainns constricted and dilates slowly
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