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Subgroups on MND
1. Progressive Muscular Atrophy
2. Amyotrophic lateral sclerosis
3. Progressive Bulbar Palsy
Degeneration in Motor Neuron Diseases
1. Anterior Horn Cells (Spinal cord)
2. Motor Nuclei of lower CN ( Brain stem)
3. Corticospinal and corticobulbar tracts
Amyotrophic Lateral Sclerosis Features
UMN and LMN degeneration:
1. Spastic (UMN)
2. Exaggerated tendon reflex (UMN)
3. Muscle Fasciculations (LMN)
Progressive Muscular Atrophy Features
LMN degeneration:
1. Muscle Fasiculations
2. Flaccid weakness
3. Abscent tendon reflexes
Features of Progressive Bulbar Palsy
1. Dysarthria
2. Dysphagia
3. Tongue Fasciculations
Myelinopathy Features
1. Leison is random and segmental
2. Autoimmune disorder
3. Weakenss
: Proximal and Distal
4. Sensory and Reflex loss
Axonopathy features
1. Degeneration of Distal Axon
2. caused by Metabolic/Toxic./ Ischaemic pathol
3. Weakness
: Distal
4. Sensory and Reflex loss
NMD associated with Pain
1. DM
2. Vasculitis
3. Radiculopathy
4. Plexopathy
5. Guillen Barre Syndrome
6. HIV
7. Syphillis
8. Amyloidosis
Sensory Neuropathies
1. Paraneoplastic
2. Sjorgen's Synd
3. Vit B6 toxicity
4. HIV related
5. Chemotherapy- Cisplatin and analogues
6. Idiopathic
Author
Rosie435
ID
127929
Card Set
NMD
Description
NMD
Updated
2012-01-15T15:38:13Z
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