Kullgren

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Agonizing Mu receptor produces

Euphoria! Remember this one
Pentazocine, nalbuphine, butorphanol
- Mu antagonist
- Kappa agonist
Buprenorphine
- Mu partial agonist
- Kappa antagonist
Phenanthrenes (6)
- Morphine
- Codeine
- Hydromorphone
- Hydrocodone
- Oxycodone
- Oxymorphone
Diphenylheptane derivatives
- Methadone
- Propoxyphene
Phenylpiperidine derivatives
- Meperidine
- Fentanyl
CNS side effects of opoids (3)
- Miosis
- N/V
- Cough suppression
Peripheral opoid side effects (3)
- Urinary retention
- Biliary spasm
- Orthostatic hypotension
Opoids caution in renal failure (2)
- morphine
- hydromorphone
- (caution in renal defficiency)
Opoinds that require metabolism (7)
- Codeine
- Morphine
- Hydrocodone
- Hydromorphone
- Oxycodone
- Fentanyl
- Methadone
Opoid agonist/antagonist (4)
- Pentazocine
- Buprenorphine
- Butorphanol
- Nalbuphine
Opoid antagonists (4)
- Naloxone
- Naltrexone
- Nalmefene
- Methylnaltrexone
Opoid-related for diarrhea (2)
- Diphenoxylate w/atropine
- Loperamide (max 16mg)
Alterations in Alzheimer's disease (4)
- Cortical atrophy (brain shrinks)
- Degeneration of cholinergic neurons
- Presence of neurofibrillary tangles
- Neuritic plaques
Targets for AD drugs (2)
- Lack of acetylcholine
- Too much glutamate
AChE Inhibitors (3)
- Donepezil
- Rivastigmine
- Galantamine
Stages of Anesthesia (4)
- Induction
- Excitement
- Surgical Anesthesia
- Impending death/overdose
Dissociative Anesthetics (2)
- PCP
- Ketamine
Opoids in anesthesia (4)
- Fentanyl
- Alfentanil
- Sufentanil
- Ramifentanil
Halogenated hydrocarbons (6)
- Halothane
- Methoxyflurane
- Enflurane
- Isoflurane
- Desflurane
- Sevoflurane
Adjunct agents (4)
- Alpha 2 agonists
- Benzos
- Analgesics
- Neuromuscular blocking agents
Local anesthetics loss of sensation (5 in order)
- 1 - Pain
- 2 - Cold
- 3 - Warmth
- 4 - Touch
- 5 - Pressure
LA Esters (4)
- Tetracaine
- Procaine
- Cocaine
- Benzocaine
LA Amides (5)
- Bupivacaine
- Ropivacaine
- Lidocaine
- Mepivacaine
- Prilocaine
Preload

Tension exerted by blood on chamber wall before systole
Afterload
- Tension developed in the chamber wall to pump blood out, determined by peripheral resistance
- Contractile force
Frank-Starling Law

Contractile forse is directly proportional to preload (more blood in ventricle = more forceful contraction)
SA node is

pacemaker
AV node slows

the signal down
L type Ca channels are on

the heart

Author

jaguavai

127466

Card Set

Kullgren

Description

Pharm 421 and so CVS intro

Updated

2012-01-12T21:56:54Z