Lori Thomas

  1. Parenteral
    A sterile, injectable medication; introduction of a drug or nutrient into a vein, muscle, subcutaneous tissue, artery, or spinal column; often refers to intravenous infusions of nutritional solutions.
  2. Sterile
    Free from microorganisms
  3. Compound Sterile Preparation (CSP)
    relates to the compounding of sterile preparations, including intravenous admixtures, ophthalmics, intrathecals, etc., prepared in a controlled sterile environment
  4. Intravenous (IV)
    Within a vein; administered drugs or fluids directly into the vein to obtain a rapid or complete effect from the drug.
  5. Intermittent infusion
    The administration of an IV infusion over a period of time followed by a period of no administration. Same cycle usually is repeated at sceduled times, hence the name intermittance
  6. Intramuscular (IM)
    within the muscle
  7. Subcutaneous (SC)
    Under the skin
  8. Intradermal (ID)
    situated or applied within the skin
  9. Intra-arterial
    the injection of a sterile preparation
  10. intra-articular
    the injection of a sterile preparation in a joint such as the elbow or knee.
  11. Intracardio
    the injection of a sterile preparation directly into the heart
  12. intraperitoneal
    a sterile preparation is injected into the peritoneal or abdominal cavity
  13. intrapleural
    a sterile preparation is injected into the sac surrounding the lungs.
  14. Intraventrical
    The injection into a ventricle of the brain or heart.
  15. Intravesicular
    a preparation instilled into the urinary bladder
  16. Intravitrial
    A sterile preparation is injected into the vitrenous chamber of the eyeball behind the lens
  17. intrathecal
    within the subdural space of the spinal cord
  18. antearea
    an ISO Class 8 or better area where personnel perform hand hygiene and garbing procedures. Staging of components, order entry, CSP labeling and other high-particulate generating activities
  19. admixture
    the term used to denote one or more active ingredients in a large volume parenteral solution
  20. aseptic processing
    a method to assure that no contamination of compounded sterile products will occur during their compounding.
  21. aseptic technique
    a method of preparation that will prevent contamination of a site (e.g. wound) or product (e.g. IV admixture).
  22. buffer area
    usually an ISO class 7 area where the laminar flow hood is located.
  23. critical area
    an ISO class 5 area
  24. critical site
    any opening or surface that can provide a pathway between the sterile product and the environment.
  25. Direct compound area
    a critical compounding area meeting ISO 5 specifications
  26. Hypertonic
    Having a higher osmotic pressure than a reference solution, usually refer to blood plasma or lacrimal fluid.
  27. Hypotonic
    having a lesser osmotic pressure than a reference standard, usually refering to blood plasma or lacrimal fluid
  28. ISO class 5 area
    International organization of standardization (ISO) Classification of particulate matter in room air, with no more than 3,520 particles per cubic meter of air 0.5 microns and larger.
  29. ISO class 7 area
    International Organization of Standardization (ISO) Classification of particulate Matter in room air, with no more than 352,000 particles per cubic meter of air 0.5 microns or larger.
  30. ISO class 8 area
    International organization of Standardization (ISO) Classification of Particulate Matter in room air, with no more than 3,520, 000 particles per cubic meter of air 0.5 microns and larger.
  31. primary engineering control (PEC)
    a device such as a laminar flow workbench, biological safety cabinet, or compounding aseptic isolator, which provides the ISO class 5 environment necessary for compounding sterile preparations
  32. Sterilizing filter
    the filters used to sieve, absorb, and entrap, foreign particles to achieve sterilization.
  33. unidirectional flow
    the air flow moving in a single direction in a robust and uniform manner to sweep particles away from the critical processing area related to laminar air flow.
  34. validation
    a proof or confirmation of validity
  35. verification
    the confirmation of a truth or fact
  36. When working in a horizontal laminar airflow hood, you must work at least _________ from the outside edge to the work surface.
    6 inches
  37. Which of the ISO classifications listed below is equvilant to a class 100 area?
    ISO class 5
  38. When working in a laminar flow hood
    You must protect all critical sites by never putting your hand or object between the critical site and the hepa filtered air.
  39. In the definition of class 100, class 10, 000, and class 100, 000 rooms, we are always talking about total particles________microns in size or larger
  40. A tubercolin skin test is given by which route or administration
  41. The compunding of a total parenteral nutrition solution could be an example of
    Medium risk level compounding
  42. When choosing a sterilizing filter must be considered
    • The volume of the product to be filtered
    • the compatability of the membrane of the product to be filtered
    • whether the solution to be filtered is hydrophobic or hydrophilic
  43. The pore size of a sterilizing filter is?
    0.2 microns
  44. A sterile product is one that is
    free from all living microorganisms
  45. An operator must successfully complete one media fill before compounding any sterile products
    correct USP media transfers
  46. Choose the most correct answer about transfering products into the antearea
    bottles, bags, and syringes must be removed from brown card board boxes before being brought into the antearea
  47. please choose the most correct conclusion to the statement; the plenum in a lamianar flow workbench is
    An area where air is pressurized for distribution over the hepa-filter
Card Set
Lori Thomas
Chapter 15 pharmacy