-
Lovenox
- Gen: Enoxaparin Sodium
- Class: Anticoagulant (LMW-heparin)
- RoA: IV
- MOA: Anti-Factor Xa and anti-thrombin (Factor IIa) activity
- Indication: DVT, PE, MI, Ischemia, (all postop and prohhylaxis)
-
Aranesp
- Gen: Darbepoetin Alfa
- Class: Erythropoietic- Hematopoietic
- RoA: IV or SC
- MOA: binds progenitor stem cells stimulating production/differentiation of erthropoiesis
- Indication: Anemia from Chronic kidney disease and Chemotherapy
-
Procrit
- Gen: Epoetin Alfa
- Class: Erythropoietic- Hematopoietic
- RoA: IV or SC
- MOA: bone marrow division/differentiation of committed erythroid progenitors
- Indication: Anemia from Chronic renal failure, Chemotherapy, or Surgical procedures
-
Revlimid
- Gen: Lenalidomide
- Class: Immune Modulator
- RoA: Oral
- MOA: inhibits cell proliferation, pro-inflammatory cytokines,
- Indication: Multiple myeloma, Myelodysplastic syndrome
-
Neulasta
- Gen: Pegfilgrastim
- Class: Colony Stimulating Factor, Hematopoetic
- RoA: SC
- MOA: A Colony Stimulation Factor- stimulates proliferation/differentiation/ activation of hematopoietic cells
- Indication: Febrile neutropenia, in pt with non-myeloid malignancies, Prophylaxis
-
Remicade
- Gen: Infliximab
- Class: Immunological agent (TNFaI)
- RoA: IV infusion
- MOA: inhibits the binding of TNF alpha
- Indication: Crohn's, Colitis, RA, psoriasis
-
Rituxan
- Gen: Rituximab
- Class: Antineoplastic agent, monoclonal antibody
- RoA: IV infusion
- MOA: binds to CD20 antigen located on pre-B lymphocytes and may promote lysis
- Indication: Lymphomas, Leukemias, RA
-
Levaquin
- Gen: Levofloxacin
- Class: Antibiotic (fluoroquinolone)
- RoA: Oral , IV, optical
- MOA: inhibits topoisomerase IV, DNA gyrase (replication, transcription, repair, recombination)
- Indication: Bronchitis, nosocomial/comm-acquired pneumonia, UTI
-
Avastin
- Gen: Bevacizumab
- Class: Immunological Agent, Monoclonal antibody
- RoA: IV infusion
- MOA: recombinant humanized monoclonal IgG1 antibody Binds to VEGF to inhibit VEGF/Flt1 & KDR interaction of epithelial cells to prevent new blood vessels
- Indication: Glioblastoma, Cancer (Colorectal, Renal cell Small cell lung)
-
-
Zosyn
- Gen: Piperacillin Sodium/Tazobactam Sodium
- Class: Antibiotic
- RoA: IV infusion
- MOA: beta-lactam antibiotic – inhibit cell wall synthesis
- Indication: Appendicitis, Pneumonia, Skin infection, Peritonitis, Puerperal endometritis
-
Neupogen
- Gen: Filgrastim
- Class: Colony Stimulating Factor, Hematopoetic
- RoA: SC
- MOA: granulocyte colony stimulating factor, binds to specific cell surface receptors regulating neutrophil production, progenitor proliferation, and differentiation
- Indication: Febrile neutropenia, harvesting peripheral stem cells
-
Eloxatin
- Gen: Oxaliplatin
- Class: Antineoplastic Agent
- RoA: IV
- MOA: undergoes monoenzymatic conversion
- Indication: Colon cancer – stage III, colorectal cancer
-
Diprivan
- Gen: Propofol
- Class: Sedative – hypnotic
- RoA: IV
- MOA: unknown
- Indication: General anesthesia, Sedation for mechanically ventilated
-
Omnipaque
- Gen: IOHEXOL
- Class: nonradiocontrast agent
- RoA: IV
- MOA:
- Indication: x-ray dye
-
Integrilin
- Gen: Eptifibatide
- Class: Glycoprotein 2b/3a inhibitor, Platelet aggregation inhibitor
- RoA: IV
- MOA: inhibits platelet aggregation by binding to GP2b/3a à prevents binding of fibrinogen, vWf, and other adhesive ligand
- Indication: Acute coronary syndrome, percutaneous coronary intervention
-
Advair Diskus
- Gen: Fluticasone Propionate/Salmeterol Xinafoate
- Class: Antiasthma, Anti-inflammatory/Bronchodilator Combination
- RoA: Inhalation
- MOA: Fluticasone – a corticosteroid – glucocorticoid receptor agonist. Salmeterol – long acting beta agonist, stimulates AC to make cAMP à relaxes bronchial smooth muscles
- Indication: Asthma, COPD
-
Sodium Chloride
- Gen: Sodium Chloride
- Class:Antiasthma, Dermatological Agent, Dressing Agent, Eye Wash, Irrigant, Moisturizer, Nutriceutical, Osmotherapy Agent, Parenteral Electrolyte, Sodium, Respiratory Agent, Sodium Supplement, Wound Care Agent
- RoA: Inhalation, Injection, Intravenous, Irrigation, Nasal, Ophthalmic, Oral, Sublingual, Topical
- MOA: principle cation of extracellular fluid
- Indication: Corneal edema, Elective abortion, Heat stroke, Hyponatremia, Hypovolemic shock, Nasal irritation
-
Zyvox
- Gen: Linezolid
- Class: Antibiotic
- RoA: IV
- MOA: inhibits ribosomal translation by binding to 23S of 50S RNA
- Indication: Pneumonia, Vanco-resistant Enterococcus faecium infection, infection of skin
-
Herceptin
- Gen: Trastuzumab
- Class: Immunological agent, Monoclonal antibody
- RoA: IV
- MOA: monoclonal antibody binds to HER2 protein to inhibit the growth of tumor cells
- Indication: Metastatic breast cancer, HER2 overexpression
-
Protonix
- Gen: Pantoprazole Sodium
- Class: PPI
- RoA: IV, nasogastric, Oral
- MOA: inhibits the pump by binding to the pump
- Indication: GERD, Zollinger-Ellison Syndrome, Gastric hypersecretion
-
Taxotere
- Gen: Docetaxel
- Class: Antineoplastic Agent
- RoA: IV
- MOA: inhibits microtubule dissembly by binding to it followed by its polymerization
- Indication: Breast cancer, Gastric cancer, Head & neck cancer, hormone refractory prostate cancer, lung cancer
-
Angiomax
- Gen: Bivalirudin
- Class: Anticoagulant, Thrombin inhibitor
- RoA: IV
- MOA: binds to catalytic site and the anion-binding exosite of circulating and clot-bound thrombin
- Indication: Heparin-induced thrombocytopenia, Thromboembolic disorder; Prophylaxis, coronary angioplasty, Unstable angina
-
Thrombin-jmi
- Gen: Bovine Thrombin
- Class: Hemostatic
- RoA: Topical
- MOA: immediately clots the fibrinogen of the blood without the aid of a physiological agent
- Indication: hemorrhage
-
Cancidas
- Gen: Caspofungin Acetate
- Class: Antifungal, glucan systhesis inhibitor
- RoA: IV
- MOA: inhibits beta-1,3-D-glucan synthesis – an important component of cell wall
- Indication: Aspergillosis, Candidemia, Febrile neutropenia
-
Ultane
- Gen: Sevoflurane
- Class: Haloalkane
- RoA: Inhalation
- MOA:
- Indication: General Anesthesia
-
Seroquel
- Gen: Quetiapine Fumarate
- Class: antipsychotic
- RoA: Oral
- MOA: inhibits 5-HT1A, 2, D1,2, H1, and α1,2
- Indication: Bipolar – 1, MDD, Schizophrenia
-
Protonix IV
- Gen: Pantoprazole Sodium
- Class:
- RoA:
- MOA:
- Indication:
-
Gemzar
- Gen: Gemcitabine Hydrochloride
- Class: antimetabolite, antineoplastic agent
- RoA: IV
- MOA: nucleoside analogue that exhibits antitumor activity which is cell phase-specific for the S-phase and for the G1/S-phase boundary of cell division.
- Indication: Breast, Ovarian, Pancreas, non-small cell lung cancers
-
Erbitux
- Gen: Cetuximab
- Class: Antineoplastic agent, Monoclonal antibody
- RoA: IV
- MOA: specifically binds to EGFR blocking phosphorylation and activation of receptor-associated kinases, resulting in inhibition of growth and survival of tumor cells that over-express the EGFR
- Indication: Head and neck cancer, Metastatic colorectal cancer
-
Visipaque
- Gen: IODIXANOL
- Class: radiological non-ionic contrast
- RoA: IV
- MOA:
- Indication: radiography
-
Primaxin
- Gen: Imipenem/Cilastatin
- Class: Antibiotic
- RoA: IM
- MOA: Inhibition of cell wall synthesis
- Indication: LRespiratory Tract, intra abdomial, skin, bynecologic infections
-
Zocor
- Gen: Simvastatin
- Class: Statin
- RoA: Oral
- MOA: HMG-CoA reductase inhibitor
- Indication: hypercholesterolemia (CHD, diabetes, stroke, MI)
-
Ms Contin
- Gen: Morphine Sulfate
- Class: Opiate Analgesic
- RoA: Oral
- MOA: CNS mu opioid receptor agonist
- Indication: Moderate to severe 24 hr pain managment
-
vancocin
- Gen: Vancomycin Hydrochloride
- Class: Antibiotic
- RoA: IV
- MOA: Inhibition of cell wall synthesis
- Indication: Methicillin-resistant staph, endocarditis
-
Nexium
- Gen: Esomeprazole
- Class: PPI
- RoA: Oral
- MOA: covalently bonds to the H/K ATPase pump
- Indication: Erosive esophagitis, GERD, NSAID-GU, H.pylori-DU, Zollinger-Ellison Sydrome
-
Plavix
- Gen: Clopidogrel Hydrogen Sulfate
- Class: Anti-coagulant
- RoA: Oral
- MOA: Irreversibly binds to P2Y12 ADP receptors on platelets to inhibit GPIIb/IIIa complex
- Indication: MI, Stroke, Peripheral arterial disease
-
Zometa
- Gen: Zoledronic Acid
- Class: Bisphosphonate
- RoA: IV infusion
- MOA: inhibits osteoclasts to lower calcium release
- Indication: Hypercalcemia of Malignacy, Multiple Myeloma, Bone Metastases
-
Gamunex
- Gen: Immune Globulin
- Class: Immune Globulin
- RoA: IV
- MOA: supplies IgG antibodies
- Indication: Primary Humoral Immunodeficiency (PI), Idiopathic Thrombocytopenia Purpura (ITP), Chronic Inflammatroy Demyelinating Polyneuropathy (CIDP)
-
Camptosar
- Gen: Irinotecan Hydrochloride
- Class: Anti neoplastic agent
- RoA: IV
- MOA: binds topoisomerase-1-DNA complex
- Indication: colon/rectum metastic carcinoma
-
Risperdal
- Gen: Risperidone
- Class: Antipsychotic
- RoA: Oral
- MOA: D2 and 5HT2 antagonists
- Indication: Schizophrenia, Bipolar,
-
Zyprexa
- Gen: Olanzapine
- Class: Antipsyhotic (Thienobenzadiazepine)
- RoA: Oral
- MOA: D2, 5HT2 antagonist
- Indication: Schizophrenia, Bipolar
-
Lupron Depot
- Gen: Leuprolide Acetate
- Class: Antineoplastic Agent
- RoA: IV, IM, ID, SC
- MOA: Gonadaltropin-releasing Hormone (GnRH), LH-RH
- Indication: Anemia, Endometriosis, Prostate cancer
-
Prevacid
- Gen: Lansoprazole
- Class: PPI
- RoA: Oral
- MOA: the sulphenamide derivative binds irreversibly to the H/K ATPase pump
- Indication: DU, GERD, NSAID-GU, Zolinger-Ellison syndrome
-
Zithromax
- Gen: Azithromycin
- Class: Antibiotic (macrolide)
- RoA: Oral
- MOA: binds 50-S ribosomal subunit (interfers with microbial protein synthesis)
- Indication: COPD, otitis media, conjunctivitis, pneumonia,gonorrhea (bacterial infections)
-
Lipitor
- Gen: Atorvastatin Calcium
- Class: HMG-CoA reductase Inhibitor
- RoA: Oral
- MOA: inhibits cholesterol synthesis, increases LDL receptors
- Indication: Hyperholesterolemia, hyper riglyceridemia, Familial type-3 hyperlipoproteinemia, CVD (prophylaxis), type 2 diabetes mellitus
-
Cubicin
- Gen: Daptomycin
- Class: Antibiotic
- RoA: IV
- MOA: binds cell membrane depolarizing membrane potential leading to disrupt DNA, RNA and protein synthesis
- Indication: Bacteremia, endocarditis, staph aureus
-
Suprane
- Gen: Desflurane
- Class: Haloalkane
- RoA: Inhalation
- MOA: increase GABA transmission
- Indication: General anesthesia
-
Cardene I.V.
- Gen: Nicardipine
- Class: Anti-HT, CCBlocker
- RoA: IV
- MOA: blocks the transmembrane influx of Ca+ affecting cardiac/SM contractility
- Indication: HT, postoperative HT, Stable angina
-
Adenoscan
- Gen: Adenosine
- Class: Adenosine R-agonist, Antiarrhythmic
- RoA: IV
- MOA: depresses Lf ventricular function (influence cellular Ca dynamics)
- Indication: Paroxysmal supraventricular tachycardia
-
Synagis
- Gen: Palivizumab
- Class: Immunological Agent, Monoclonal Antibody
- RoA: IM
- MOA:exhibits neutralizing and fusion-inhibitory activity
- Indication: Repiratory syncytial virus infection (RSV)
-
Zofran
- Gen: Ondansetron
- Class: 5-HT3 Antagonist, Antiemetic
- RoA: Oral
- MOA: blocking 5-HT3 peripherally on vagal nerve terminal in CTZ (chemoreceptor trigger zone)
- Indication: Chenotherapy/Radiation N/V
-
Prilosec
- Gen: Omeprazole
- Class: PPI
- RoA: Oral
- MOA: irreversibly binds H/K ATPase pumps
- Indication: DU, GU, GERD, erosive esophagitis, gastric hypersecretion
-
Rocephin
- Gen: Ceftriaxone Sodium
- Class: Antibiotic (3rd Gen cephalosporin)
- RoA: IM, IV
- MOA: inhibition of cell-wall synthesis
- Indication: UTI, LRTI, gonorrhea,
-
Zemuron
- Gen: Rocuronium Bromide
- Class: Neuromuscular Blocker, Musculoskeletal agent
- RoA: IV
- MOA: competes for cholinergic receptors at the motor end-plate
- Indication: General anesthesia
-
Alimta
- Gen: Pemetrexed
- Class: Antineoplastic Agent
- RoA: IV infusion
- MOA: disrupts folate-dependent metabolic processes for cell replication
- Indication: mesothelioma, small cell lung cancer
-
Maxipime
- Gen: Cefepime Hydrochloride
- Class: Antibiotic (4th Gen Cephalosporin)
- RoA: IM, IV
- MOA: inhibits cell wall synthesis
- Indication: Pneumonia, UTI, infections
-
Novoseven
- Gen: Coagulation Factor VIIA
- Class: Hemostatic
- RoA: IV bolus
- MOA: promotes hemostasis by complexing tissue factor activating coagulation facotrs in intrinsic pathway
- Indication: Hemophilia, Factor VII, VIII deficiency
-
Lantus
- Gen: Insulin Glargine, Recombinant
- Class: Antidiabetic (long acting insulin)
- RoA: SC
- MOA: Stimulates glucose uptake by muscle
- Indication: Diabetes mellitus type 1 & 2
-
Optiray 320
- Gen: Ioversol
- Class: non radial contrast agent
- RoA: IV
- MOA:
- Indication: diagnostic radiology
-
Activase
- Gen: Alteplase, Recombinant
- Class: Thromolytic (tissue plasminogen activator)
- RoA: IV
- MOA: enhances plasminogen to plasmin by binding fibrin initiating fibrinolysis,
- Indication: Acute MI & Ischemia, PE, venous catheter occlusion
-
Merrem
- Gen: Meropenem
- Class: Antibiotic (Beta-Lactam, carbapenem)
- RoA: IV
- MOA: inhibiting cell wall synthesis
- Indication: bacterial infections, meningitis, subcutaneous complication
-
Epogen
- Gen: Epoetin Alfa
- Class: Erythropoietic, Hemotopoietic
- RoA: IV, SC
- MOA: stimulates division/differentiation of committed erythroid progenitors
- Indication: Anemia (cancer, renal failure, Zidovudine AR, transfusion)
-
Reopro
- Gen: Abciximab
- Class: Anticoagulant
- RoA: IV
- MOA: block platelet aggregation by binding GP IIb/IIa receptor preventing fibrinogen and other AC proteins
- Indication: MIschemia, Refractory Angina (adjunct)
-
Isovue-300
- Gen: Iopamidol
- Class: Non radial constrast agent
- RoA: IV
- MOA:
- Indication: diagnostic radiology
-
Aciphex
- Gen: Rabeprazole Sodium
- Class: PPI
- RoA: Oral
- MOA: covalently binds H/K ATPase pump
- Indication: GU, DU, GERD, erosive esophagitis, Gastric Hypersecretion, H.pylori therapy
-
Fentanyl
- Gen: Fentanyl
- Class: Analgesic (opioid)
- RoA: SubLingual, Transdermal
- MOA: CNS mu receptors
- Indication: moderate-severe pain (opioid-tolerant)
-
Combivent
- Gen: Ipratropium Bromide/Albuterol Sulfate
- Class: Bronchodilator
- RoA: Inhalation, Nebulization
- MOA: Albuterol- beta2 agonist(SM relaxation)
- Ipratropium- anticholinergic agent (site-specific bronchodilation)
- Indication: COPD
-
Zoladex
- Gen: Goserelin Acetate
- Class: Antineoplastic agent, LHreleasing hormone agonist
- RoA: SC
- MOA: Inhibits/suppresses the pituitary gonadotropin secretion
- Indication: Breast cancer, endometriosis, prostate cancer
-
Abilify
- Gen: Aripiprazole
- Class: Antipsychotic
- RoA: Oral, IM
- MOA: Agonist at D2 and 5HT1A, antagonist 5HT2A
- Indication: Schizophrenia, Bipolar, MDD, Autistic (agitation)
-
Singulair
- Gen: Montelukast Sodium
- Class: Anti-Inflammatory (leukotriene pathway Inhibitor)
- RoA: Oral
- MOA: binds cysteinyl leukotrienes (CysLT) type-1 in airway to prevent edema, SM contraction and respiratory inflammation
- Indication: Asthma, Exercise-induced A, perennial and seasonal allergic rhinitis
-
Enbrel
- Gen: Etanercept
- Class: Immune Suppressant (TNFalpha inhibitor)
- RoA: SC
- MOA: Binds to TNFa,b receptor inactivation inflammatory/ immune response, and other cytokines
- Indication: RA, Juvenile Idiopathic arthritis, Psoriasis
-
Magnevist
- Gen: Gadopentetate Dimeglumine
- Class: Non-ionic contrast media
- RoA: IV
- MOA:
- Indication: Diagnostic Radiology
-
Argatroban
- Gen: Argatroban
- Class: Anticoagulant
- RoA: IV
- MOA: binds active thrombin site to inhibit
- Indication: Coronary Artery Thrombosis, Heparin-induced Thrombocytopenia
-
Thymoglobulin
- Gen: Lymphocyte Immune Globulin
- Class: Immune Supressant
- RoA: IV
- MOA: Clears and suppresses T-cell activation
- Indication: Renal transplant rejection (adjunct)
-
Novolog
- Gen: Insulin Aspart, Recombinant
- Class: Antidiabetic (rapid acting insulin)
- RoA: SC
- MOA: binds insulin receptors on muscle and fat cells to increase glucose uptake
- Indication: Diabetes mellitus types 1 & 2
-
Ambisome
- Gen: Amphotericin B Liposome
- Class: Antifungal (polyene)
- RoA: IV
- MOA: binds to ergosterol in cell membranes causing permeability, leaking and cell death
- Indication: fungal infections (aspergillosis, candidiasis, meningitis-HIV, pumonary aspergillosis)
-
Cipro IV
- Gen: Ciprofloxacin
- Class: Antibiotic (Fluoroquinolone)
- RoA: IV, Oral
- MOA: Interference of DNA gyrase(DNA synthesis)
- Indication: bacterial infections (Anthrax, gonorrhea, bronchitis, nosocomial pneumonia, LRTI, UTI)
-
Sandostatin Lar
- Gen: Octreotide Acetate
- Class: Somatostatin (Endocrine-metabolic agent)
- RoA: SC, IV, IM
- MOA: reduces growth hormone, LH, GnRH
- Indication: Acromegaly, Carcinoid Syndrome, Vasoactive Intestinal Peptide-Secreting Tumor
-
Keppra
- Gen: Levetiracetam
- Class: Anticonvulsant
- RoA: IV, Oral
- MOA: prevents hypersynchronization of epileptiform burst firing and propagation
- Indication: Partial, Myoclonic, Tonic-clonic Seizures
-
Albuminar-25
- Gen: Albumin Human
- Class: Volume Expander
- RoA: IV
- MOA: increases volume and plasma
- Indication: ARespiratory Distress, Ascites, Burns, liver failure, Nephropathy, Pancreatits
-
Botox
- Gen: Onabotulinumtoxin-A
- Class: Musculoskeletal agent, Botulinum Toxin Type A
- RoA: IV, IM
- MOA: blocks neuromuscular conduction on motor nerve terminals, inhibiting acetylcholine release
- Indication: Blepharospasm, headache, hyperhidrosis of axilla, incontinence (detrusor instability), strabismus, upper limb spasticity, wrinkled face
-
Venofer
- Gen: Iron Sucrose
- Class: Parenteral Mineral-Trace Mineal
- RoA: IV
- MOA: dissociates to iron and sucrose components, increases iron, ferritin levels, decreases total iron binding capacity
- Indication: Iron deficiency anemia
-
Paclitaxel
- Gen: Paclitaxel
- Class: Antineoplastic agent, Mitotic Inhibitor
- RoA: IV
- MOA: enhances the cytotoxic effects of ionizing radiaion
- Indication: Breast, Ovarian, small cell lung cancer, AIDS-related Kaposi's sarcoma
-
Effexor Xr
- Gen: Venlafaxine Hydrochloride
- Class: Antidepressant (phenethylamine- SNRI)
- RoA: Oral
- MOA: inhibits 5HT, NE, Da reuptake
- Indication: GAD, MDD, Panic disorder, Social Phobia
-
Neurontin
- Gen: Gabapentin
- Class: Anticonvulsant (GABA enhancement)
- RoA: Oral
- MOA: increases GABA
- Indication: Partial Seizure, Postherpetic Neuralgia
-
Aloxi
- Gen: Palonosetron Hydrochloride
- Class: Antiemetic (5HT3 antagonist)
- RoA: IV
- MOA: inhibits the vomiting reflex
- Indication: Chemotherapy-induced N/V
-
Gardasil
- Gen: Human Papillomavirus Vaccine
- Class: Vaccine
- RoA: IM
- MOA: develops humoral immune response against paps 6, 11, 16, and 18.
- Indication: viruses associated with cancer treatment
-
Trasylol
- Gen: Aprotinin
- Class: Hemostatic
- RoA: IV
- MOA: unknown but maintains platelet function, prevents fibrinolysis
- Indication: Hemorrhage (surgery)
-
Xigris
- Gen: Drotrecogin Alfa
- Class: Anticoagulant, Profibrinolytic
- RoA: IV
- MOA:
- Indication: Sepsis syndrome from organ dysfuction (pulled from market)
-
Glucophage
- Gen: Metformin Hydrochloride
- Class: Biguanide, Hypoglycemic
- RoA: Oral
- MOA: 1. decreases hepatic glucos production
- 2. decreases intestinal absorption,
- 3. increases peripheral glucose uptake
- 4. improves insulin sensitvity
- Indication: Diabetes Mellitus type 2
-
Xopenex
- Gen: Levalbuterol
- Class: Bronchodilator (Beta-2 agonist)
- RoA: Inhalation
- MOA: relaxation of airway SM
- Indication: Asthma
-
Prograf
- Gen: Tacrolimus
- Class: Antipsoriatic, Immune Suppressant, Calcineurin Inhibitor
- RoA: IV, Oral, topical
- MOA: Inhibits T-lymphocyte activation, and other cytokines
- Indication: transplant rejection, atopic dermatitis
|
|
