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"TOM"
- Short-acting BDZs
- Triazolam
- Onazelam
- Midazolam
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Butyrophenone
Haloperidol & Droperidol
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Atypical D4
Clozapine - Thioridazine - Olanzepine - Risperidone = do not cause EPS
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Flumazenil
BDZ antidote for OD
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Phenytoin
Causes aplastic anemia / gingival hyperplasia / cleft lip & platelet
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Thiopental
Short acting Barb
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Carbamazepine
- DOC thrgeminal neuralgia
- Tx lennox gestaut seizures in kids
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Atypical D4-r
Thioridazine; Olamzapine; Clozapine
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Pimozide
Tx for Tourette's
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Risperidone
Good for negative symptoms
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Thioridazide
Most anti-cholinergic neuroleptic
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Haloperidol
Neuroleptic malignant hyperthermia due to chronic D2 block. Give Dantrolene and Bromocriptine
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Clomirpramine
- Tx OCD
- See aggressive behavior with use
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Bupropion
Helps quit smoking
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SSRI's
Primarily used for OCD
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Fluoxetine
Good for negative symptoms
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Phenelzine
Irreversible MAOI
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Lithium
- Tx manic phase of Bipolar Disorder Causes goiter by (-) conversion of T4 to T3
- Nephrogenic diabetes insipidus
- Low Salt diet will lead to Li toxicity
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Alprazolam
DOC for stage fright
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Propranolol
Social phobia
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kapaa-r
- Spinal analgesia, Euphoria
- ++ euphoria, ++ sedation
- Constipation
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mu-r
- Supraspinal analgesia, Dysphoria
- +respiratory depress, + sedation
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Morphine & O2
Admin is contraindicated to pts on morphine sedation = decreased CO2 sensitivity and O2 administration can stop breathing
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Morphine
Increase ICP = do not give to pt with head trauma
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Morphine OD
- Pinpoint pupil
- Decreased respiration
- Coma
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Meperidine
Anesthetic used during labor
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Hydromorphane
mu (+) used in renal failure
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Tramadol
Ambulatory tx for mod to severe pain
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Naloxone
- Tx for opioid ODReverse respiratory depression
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Pentazocine
Part kappa(+) & part mu(-)
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Butorphenol
Part kappa(+) & part mu(-)
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Nalbuphene
Part kappa(+) & part mu(-)
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Decreased GABA
Decreased seizure focus = Barbs and BDZs
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Fast Na Ch
Decreased electrical activity spread = Phenytoin & Carbomazepine
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Methoxyflurane
can be nephrotoxic, needs low MAC for anesthetic induction
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Enflurane
can cause tonic /clonic seizures
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Isoflurane
can cause bronchospasm
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Halothane
Can cause ventricular extrasystoles & malignant hyperthermia & hepatitis
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Nitric Oxide
No effect on HR, Needs high MAC for anesthetic induction
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Thiopental
Short acting barb
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Kentamine
Dissociative anesthetic
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Droperidol
- Can be used in combo w/ Fentanyl for neuroeptoanalgesic effect
- Neruoeptic tranquilizer, has mild alpha block
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Fentanyl
- Can be used in combo w/ Droperidol for neuroeptoanalgesic effect
- Used transdermally for chronic pain
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Midazolam
Pre anesthetic, Induces anmesia
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Primidone
Biotransformed to Phenobarb
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C and A Delta Fibers
First fibers to be blocked with anesthesia
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Esters
- Procaine, Tetracaine, Benzocaine
- Broken down and make PABA (allergen)
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Amides
- Lidocaine, Mepivacine, Bupivacine, Etidocaine = "i" before "caine" always amide
- Metabolized in liver
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Amphetamine
DA reuptake (-)r. MAOI. Parkinson's tx
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Bromocriptine
D2(+), used with L-Dopa for "on-off" phenomenon for Parkinson's
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Benztropine
Ant M w/ some DA reuptake (-). Parkinson's tx
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Amantidine
- Decreases DA reuptake
- can cause livido reticularis = skin mottling
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Diphenhydramine
Tx early Parkinson's Stages
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Pergolide
> effective & longer acting than Bromocriptine
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Ethosuzimide
DOC for absence seizures
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Tranylcypromine
MAOI - antidepressant
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SSRI & MAOI
Fatal combo, especially seen with the used of Paroxetine or Fluoxetine (SSRI) adn Tranylcypromine (MAOI)
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Labor Opioids
Meperidine & Nalbuphine
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Desipramine Causes
Sudden cardiac in children
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