MED-Midazolam

Benzodiazepine (short-acting)

• -Intensifies GABA
• -CNS Depressant
• -Anticonvulsant
• -Anterograde Amnestic
• -Skeletal muscle relaxant
• -Induces sleep

• -Status epilepticus
• -To induce sedation prior to painful procedures

• -Hypersensitivity
• -Acute narrow-angle glaucoma
• -Coma
• -Shock
• -Acute alcohol intoxication

• -COPD/CHF
• -Renal failure

• -N/V
• -Blurred vision
• -Retrograde amnesia
• -Excessive amnesia
• -Apnea
• -Hypotension
• -PVCs

• -Other CNS depressants (causes prolonged respiratory depression)
• -Alcohol
• -Cimetidine (increases plama levels of versed)

ADULT

1- 2.5 mg slow IVP or IM q 5 mins until seizure stopped

PEDI

.1 mg/kg max 6 mg may repeat in 5 minutes

• Onset=3-5 mins IV
• Duration= less than 2 hours IV
• Half Life= 4 hours