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MED-Midazolam
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Functional Class
Benzodiazepine (short-acting)
Mechanism of Action
-Intensifies GABA
-CNS Depressant
-Anticonvulsant
-Anterograde Amnestic
-Skeletal muscle relaxant
-Induces sleep
Indications
-Status epilepticus
-To induce sedation prior to painful procedures
Contraindications
-Hypersensitivity
-Acute narrow-angle glaucoma
-Coma
-Shock
-Acute alcohol intoxication
Precautions
-COPD/CHF
-Renal failure
Side Effects
-N/V
-Blurred vision
-Retrograde amnesia
-Excessive amnesia
-Apnea
-Hypotension
-PVCs
Interactions
-Other CNS depressants (causes prolonged respiratory depression)
-Alcohol
-Cimetidine (increases plama levels of versed)
Dosage
ADULT
1- 2.5 mg slow IVP or IM q 5 mins until seizure stopped
PEDI
.1 mg/kg max 6 mg may repeat in 5 minutes
Pharmacokinetics
Onset=3-5 mins IV
Duration= less than 2 hours IV
Half Life= 4 hours
Author
amerelman
ID
12379
Card Set
MED-Midazolam
Description
MED-Midazolam
Updated
2010-03-29T18:55:01Z
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