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Leptin, Adiponectin, TNFa & IL6 (Sands)

  1. Adiponectin
    • adipose derived cytokine
    • down regulated in obese
    • decreases inflammation
    • inc. FA oxidation, dec. FA synthesis
  2. Leptin
    • associated w/fat (higher in women)
    • dec. food intake, inc. energy expenditure
    • hypertension
    • increases inflammation
    • inhibits bone formation
    • Affects reproduction, puberty, pregnancy
  3. TNF-alpha
    • cytokine
    • inc. serum FA
    • inc. insulin resistance - impairs signaling
    • dec. adiponectin
    • inc. IL1 & IL6
  4. IL-6
    • inc. FFA & fatty oxidation
    • inc. serum glucose
    • down regulates IRS-1, GLUT4, adiponectin
Author
catitasilva
ID
122857
Card Set
Leptin, Adiponectin, TNFa & IL6 (Sands)
Description
Leptin, Adiponectin, TNFa & IL6 (Sands)
Updated

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