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Antigenitcity depends on:
- chemical structure
- foreigness
- complexity
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When antigen binds to its appropriate antibody:
- agglutination may ocur
- phagocytosis may occur
- antigen neutralization may occur
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Antibodies are produced by
plasma cells
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An immunoglobulin contains:
two heavy and two light polypeptide chains
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The antibody class having the highest concentration in the blood is
IgG
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Which antibody is matched with its appropriate role?
IgM/ first to challenge the antigen
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The primary immune response involves :
a latent period followed by peak antibody production
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Which cells are phagocytic
macrophages
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When a child develops measles and aquires an immunity to subsequent infections, the immunity is:
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What is adaptive immunity?
is a state of protection, primarily against infectious agents. that differs from inflammation by being slower to develop, being more specific and having memory that makes it much longer lived
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What is natural immunity?
it is innate resistance and quired immunity is gained after birth
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What are antigens?
they are molecules that react with components of the immune response such as antibodies and receptors on B and T cells. Most antigens can induce an immune response and thus antigens are also immunogens
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What are self-antigens?
they are antigens on an individual's own cells. The individuals immune systems does not normally recognize self -antigens as immunogenic, conditions known as tolerance.
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What is the Hummoral Immune Response?
- it is provided by molecules (antibodies) produced by the Bcells
- Antibodies are plasma glycoproteins that can be classified by chemical sturcture and biologic activity as IgG, IgM, IgA, IgD, IgE
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What is Cell-Mediated Immune Response?
- T cells are responsible for the cell mediated immune response
- there are several types: cytotoxic T (Tc), regulatory, T helper (Th), and T suppression, and memory cells.
- Development of cell mediated or humoral immune responses usually depends on population of Th cells
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How do T Cells respond?
T Cells have antigen specific receptors that must see antigen presented on cell surfaces by special antigen prestenting molecules of the major hisocompatibility complex (MHC molecules)
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Where do T and B cells migrate to?
Immunocompetent T and B cells migrate from primary lymphoid organs into the circulation and secondary lymphoid organs to await antigen.
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