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An increase in percentage of water vapor in the air would cause the partial pressure of oxygen to:
Decrease
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Which of the muscles are important in forced respiration?
External intercostals and sternocleidomastoid
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The _____ is lined with mucosa to remove particulates from the respiratory tract
Conducting zone and respiratory zone
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Restrictive disorders reduce:
Compliance, distensibility, and vital capacity
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Compliance is the tendency of the lungs to _____ and is necessary for ______
Expand, inspiration
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Surfactant produced by _____ prevents the alveoli from collapsing during expiration
Type II alveolar cells
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The _____ attaches to the vocal folds and swivels to regulate their tension
Arytenoid cartilage
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The total lung volume includes the vital capacity and _____.
Residual volume
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Hemoglobin saturation increases as a result of which of the following?
Increasing pH
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An increase in pCO2 will result in _____ dissociation of oxygen from hemoglobin
Increased
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Digestion
- The area of most abundant true goblet cells is:
- Colon
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Which of the following inhibits stomach secretion and motility while simultaneously stimulating bile release, pancreatic enzyme release, and relaxation of the sphincter of Oddi?
CCK
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Amino acids are absorbed into mucosal cells principally by:
Active co-transport
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Negative feedback on stomach secretin and motility as acid chime reaches the duodenum results from the secretion into the bloodstream of:
GIP
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The lining of the esophagus is:
Pseudostratified columnar epithelium
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Peyer�s patches are lymph nodules found mostly in the:
Ileum
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Which of the following is a brush border enzyme?
Maltase
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Pepsinogen is secreted by:
Chief cells located only in the stomach
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The pyloric sphincter is forcefully constricted and other stomach muscle inhibited by:
Enterogastric reflex
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The hierarchy of enzyme function ______ must act before ____ can act
Typsin before aminopeptidase
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The ____ stimulates gastric secretion during the cephalic phase and as a result of physical contact in the stomach
Vagus nerve
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Three distinct bands of longitudinal smooth muscle are found in the:
Colon
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The upper third of the esophagus has:
Skeletal muscle only
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____ is/are responsible for emulsifying fats
Bile salts
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Absorption of water occurs mostly in the:
Small intestines
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Three distinct layers of smooth muscle are found in the:
Stomach
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If you see villi and goblet cells you are looking at the:
Small intestines
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Positive feedback on stomach secretion and motility as acid chime reaches the pylorus results from the secretion into the bloodstream of:
Gastrin
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Which of the following is/are true sphincters?
Pyloric and ileocecal sphincters
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The ____ has Brunner�s glands which secrete an acid-neutralizing mucus
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Hypersecretion of insulin occurs in:
Diabetes Type II and reactive hypoglycemia
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(T/F) Fats are lipolyzed to glycerol and fatty acids when glycogen stores begin to run low
True
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The primary hormone in the absorptive phase of glycemic regulation is:
Insulin
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(T/F) Fats are readily converted to glucose when glycogen stores run low
False
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The hormone which stimulates lipolysis is:
Epinephrine and glucagon
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An excessive amount of ___ can cause hypoglycemia
Insulin
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Deamination results in molecules of ____ which are exceted through the kidneys
Urea
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Management of diabetes Type I is through:
Administration of insulin
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Diabetes type I results from damage to the ___ pancreatic islet cells which secrete insufficient amounts of _____.
Beta, insulin
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The hormone which stimulates glucose synthesis from amino acids during severe stress conditions is:
Cortisol
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Most reabsorbed substances enter the interstitial fluid and the ______:
Peritubular capillaries
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The hormone instrumental in facultative absorption of water is:
ADH
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In the countercurrent exchange of salt, NaCl is taken fro the medulla into the _____ only to be returned to the medulla from the _____:
Descending limb of the vasa recta, ascending limb of the vasa recta
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Most reabsorption of water occurs from the:
Proximal convoluted tubule
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Deficient secretion of ____ produces diabetes insipidus
ADH
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Stimulation by the sympathetic nervous system causes _____ of the ______.
Vasoconstriction, afferent arteriole
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Aldosterone-controlled salt reabsorption occurs from the:
Distal convoluted tubule
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The _____ is lined completely with transitional epithelium for stretchability.
Urinary bladder
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In response to direct stimuli by the macula densa cells the:
Afferent arteriole vasodilates and the efferent arteriole vasoconstricts
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The substance produced in response to renin which causes vasoconstriction in the efferent arteriole and arterioles is:
Angiotensin II
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Which of the following is a normal constituent of urine:
Urea
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The substance ____ is released by the juxtaglomerular cells when stimulated by the macula densa.
Renin
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When large amounts of acid must be secreted the H+ are neutralized with amines and made into:
Ammonium ions
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The cells which sense flow rate and salt concentration in the distal convoluted tubule are the:
Macula densa cells
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The process of secretion occurs in all the following except:
The loop of Henle
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Cortical blood vessels served by the efferent arteriole are the:
Peritubular capillaries
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Facultative water reabsorption occurs from the:
Collecting tube
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The hormone, also known as vasopressin, which produces arteriole vasoconstriction when secreted in response to reduced blood volume is:
ADH
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Most reabsorption of glucose occurs from the:
Proximal convoluted tubule
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The ____ lead directly to the afferent arterioles.
Interlobular arteries
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Co-active transport is instrumental in the reabsorption of:
Glucose
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The blood vessels leading directly to the glomerulus are the:
Afferent arterioles
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Most reabsorption of glucose occurs from the:
Proximal convoluted tubule
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When the blood is not acidic the most common cation secreted is:
K+
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The inner medulla is very _____ due to the countercurrent exchange of salt.
Hypertonic
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Direct myogenic response to increased blood pressure produces ____ in the _____.
Vasodilation, afferent arterioles
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ACTH stimulates the release of all of the following except:
Testosterone and epinephrine
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Which of the following hormones is produced by neurons origination in the hypothalamus:
Oxytocin and ADH
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Secretion of PTH is triggered by:
Decreased plasma calcium levels
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Releasing and inhibition hormones from the hypothalamus control hormones released from the:
Adenohypophysis
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The hormone which responds to infant sucking to produce continued milk after birth is:
Prolactin and oxytocin
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Acromegly is a disorder associated with hypersecretion of:
GH
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Which of the following stimulates protein synthesis along with both carbohydrate and fat catabolism?
GH
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A decrease in plasma calcium levels triggers the secretion of:
PTH
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The hormone which stimulates contration of uterin smooth muscle to produce labor is:
Oxytocin
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Which of the following g is NOT a cland controlled directly by plasma substrate levels:
Thyroid follicular cells (Islets of Langerhans, thyroid parafollicular cells, and parathyroid gland all controlled by substrate levels)
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Reproduction/Endocrine
- The ____ is directly stimulated by plasma levels of substrate.
- Thyroid parafollicular cells, pancreas, parathyroid gland
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Which of the following enters the nucleus of target cells to increase their basal metabolic rate?
T3
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The hypothalamus directly controls the ___ through releasing and inhibiting hormones.
Adenohypophysis
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In response to ___ the primary oocyte becomes ____.
LH, secondary oocyte
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The hormone _____ is responsible for maintaining the corpus luteum during the ovulatory cycle.
LH
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The uterine ____ phase and the ovarian ____ phase occur together.
Proliferative & follicular and secretory & luteal
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The ____ stores hormones released from neurons originating in the hypothalamus
Neurohypophysis
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The hormone ___ is responsible for maintaining the corpus luteum during early pregnancy.
HCG
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Produces semen containing acid phosphatase which activates the spermatozoa.
Prostate
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The corpus luteum produces ______.
Estrogen and progesterone
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The ____ is directly stimulated by the hypothalamus and not part of the hypothalamic-pituitary control mechanism.
Adrenal medulla
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The substance ____ feeds back to the hypothalamus to regulate spermatogenesis.
Inhibin
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The hormone _____ is the primary cause of the ovary�s follicular phase
FSH
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The hormone ___ is the primary hormone produced by the ovary during its follicular phase.
Estrogen
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The hormone ____ is produced by the ovary during its lueal phase.
Estrogen and progesterone
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In direct response to TRH, the _____ will secrete _____.
Anterior pituitary, TSH
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The hormone _____ is the primary cause of the uterine proliferative phase.
Estrogen
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Parafollicular cells of the thyroid produce:
Calcitonin
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A venous network which helps to maintain a temperature in the testicle which is several degrees below body temp.
Pampiniform plexus
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As a result of increased energy demand, ____ is released by the hypothalamus.
TRH
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Produces most seminal fluid containing nutrients and bicarbonate.
Seminal vesicle
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The portion of the uterus not subject to cyclic exfoliation is:
Cervix
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At birth a woman has a limited number of ____ which are found inside the ____.
Primary oocytes, primordial follicles
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In the male ____ acts on the sustentacular (nurse) cells to cause the production of ____ which interacts with ___ causing spermatogenesis.
FSH, Androgen binding protein, testosterone
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The tissue that responds to hormonal stimulation in cyclic buildup and exfoliation is:
Stratum functionalis of the endometrium
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In response to ____ the mature follicle becomes _____.
LH, Corpus luteum
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An interarterial anastomosis:
Provides collateral circulation of blood to a tissue or organ to compensate for a partial blockage.
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An example of an arteriovenous anastomosis would be:
In the GI tract where blood is decreased during exercise
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Gives rise to the umbilical artery
Internal iliac artery
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Sends blood from the pulmonary to the systemic division in the fetus
Ductus arteriosus
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A branch from the right coronary artery:
Marginal artery
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Fetal vessel which bypasses the liver:
Ducus venosus
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GIves rise to the splenic, common hepatic, and left gastric arteris:
celiac trunk
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Which of the following are active phagocytes:
neutrophils and monocytes
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Erythropoietin increases the _____ of red blood cell production.
Rate and proportion compared to wbc and platelets
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Coumadin competes with _____ for receptors which stimulate production of clotting proteins.
Vitamin K
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Calcium ions are important for the:
Intrinsic, extrinsic, and common clotting pathways
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Activaltion of genes that produce fetal hemoglobin can be used to manage sickle cell anemia because it has no ____ globin chains.
beta
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Rouleaux is:
The tendency of red blood cells to stack up together before entering a capillary in single file.
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The thin tan layer of white cells and platelets found at the end of the formed elements in an hematocrit tube is called the:
Buffy coat
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Most carbon dioxide is transported:
as an equilibrium between carbonic acid and its dissociation products
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Before a clot forms, a _____ may be sufficient to produce hemostasis in damaged capillaries.
a platelet plug
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The substance _____, produced by recombinant bacteria, is used to reduce damage in thrombosis occurring in embolitic stroke and myocardial infarction.
TPA (tissue plasminogen activator)
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Your blood is redirected to the local areas of the skin during cold temperatures to avoid tissue damage. This is due to:
autoregulation
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Your blood is directed away from the skin during cold temperatures. This is due to:
the vasomotor center
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The pulse pressure is absent in the:
Veins, venules, and capillaries
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The pulse pressure disappears (ends) in the:
arterioles
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The Net Filtration Pressure (NFP) is considered negative (inward flow) at the:
venous end of the capillaries
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The muscular pump works together with _____ to move blood toward the heart where the pressure gradient is insufficient.
semilunar valves
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The greatest cross sectional area for the entire vascular component is found in the:
capillaries
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Stretched veins and/or semilunar valves:
varicose veins
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Inflammation of a veins, often resulting in sluggish blood flow
phlebitis
- A blood clot in a vessel
- thrombosis
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Obstruction of a blood vessel, usually by a clot which has moved from a different location
embolism
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A balloon-like bulge in the wall of an artery
aneurism
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Smooth muscle is proportionally the greatest component of the tunica media in:
muscular arteries
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The type of capillaries found in the spleen is the:
sinusoids
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A smooth lining for the vessels
endothelium
- A cell important in repair and replacement of capillaries
- pericyte
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A pore which allows increased size and rate of transport
fenestration
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Gaps within tight junctions which allow molecular transport
intercellular cleft
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Essentially the basement membrane, it contains collagen and othe pro-coagulants
subendothelum
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Water and solutes which accumulate in the interstitial fluid from capillary filtration are returned to the circulation through:
the lymph system
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As a result of exercise the cardiac center receives input from the:
the hypothalamus
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A symptom of hemorrhagic loss of blood would be:
increased heart rate
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The closing of the AV valves is due to:
increasing ventricular pressure
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The mechanism called _____ maintains the moment to moment cardiac output and pressure.
the baroreceptor reflex
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The long refractory period exhibited by myocardial cells is indicated by diagram number:
2
- Which of the following will decrease cardiac output?
- Increased ESV and increased peripheral resistance
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This letter would be missing in sinus nodal block.
P wave
- The ECG with a missing QRS peak shows:
- Heart block
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The posterior interventricular artery forms an interaterial anastomosis with vessel _____ to provide collateral circulation to the myocardium.
Anterior interventricular artery
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Increasing pressure due to ventricular contraction closes which valves?
Tricuspid and bicuspid valves
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Between points B and C increased myocardial stretch will lead to _____ contractility.
Decreased
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An increase in the threshold of the hearts nodal myogenic cells will:
Decrease the rate of autorhythmicity
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The second heart sound occurs as a result of valve closure due to:
Ventricular relaxation
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Which of the following work as part of lymphokinetic motion in humans?
Smooth muscle in lymphatic vessels and downward pressure gradient in lymph system.
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The labeling of antigens to make them more visible to phagocytes is called:
Opsonization
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The lowest hydrostatic pressure is found in the:
large veins of the circulation
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Which of the following work as part of the muscular pump in lymphokinetic motion in humans?
semilunar valves in lymphatic vessels
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The _____ secrete interleukins I and II in response to contact with an activated macrophage.
Helper T-cells
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The location of immunocopetence of T-cell lymphocytes is the:
thymus
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The antibody receptors on immunocompetent B cells
IgD
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Gamma globulins, these ultimately make up the bulk of the antibodies produced in response to infection
IgG
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These are pentamers, and the first type of antibodies produced in response to infection
IgM
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These antibodies are found in the body's secretions
IgA
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These antibodies are produced in response to an allergen which is not pathogenic
IgE
- Which of the following would you see in the ECG as the result of electrolyte imbalance:
- The presence of a prominent U wave
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Which of the following would you see in the ECG as the result of ischemia or myocardial infarction:
- An abnormal or extra Q wave
- Excessive elevation of the ST segment
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Increasing the peripheral resistance would have a:
negative inotropic effect
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Contractility and afterload are _______.
inversely related
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Contractility and preload are _______.
directly related
- The superior mesenteric vein joins the _____ to produce the _____.
- splenic vein, hepatic portal vein
- The left gastric, common hepatic, and splenic arteries are all branches from the:
- celiac trunk
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Explain what a beta blocker does that produces a negative inotropic (force related) effect.
Beta blockers block sympathetic stimulation of the myocardium, thus reducing its contractility.
- Describe specifically how the cardiac cycle DIAGRAM would differ for the right heart compared to one for the left heart that we normally view.
- The systolic pressure would be approximately one fifth as much in the right heart than in the left heart.
- Identify the mechanism which results in rapid pulse rate as a result of hemorrhage.
- Baroreceptor Reflex
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The principle which describes the length-tension relationship for the heart is known as:
Frank-Starling Law
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What does the kidney secrete that influences oxygen transport in the blood?
Erythropoietin
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An increase in the threshold of the hearts myogenic cells will:
decrease the rate of autorhythmicity
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The principle cause of an increased EDV is:
Increased venous return
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An increase in EDU combined with a decrease in ESV will result in:
Increased cardiac efficiency, increased stroke volume, increased preload and decreased afterload
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