pharmacology final

  1. What are the ESKAPE organisms?
    • organisms that cause the most hospital infections annually
    • Enterococcus faecium
    • Staph. aureus
    • Klebsiella pneumoniae
    • Acinetobacter baumanii
    • Pseudomonas aeruginosa
    • Enterobacter specie
  2. How is chloramphenicol metabolized and excreted?
    chloramphenicol is first metabolized in the liver (glucoronidation) and then excreted by the kidneys
  3. Why are sulfamethoxazole and trimethoprim administered together (e.g. Bactrim)?
    • synergistic effect of sulfa/trim combo
    • work on different parts of folic acid pathway (sulfa: DHPS, tri: DHFR)
    • either in 5:1 or 20:1 ratios of sulfa:tri
Author
flucas
ID
120764
Card Set
pharmacology final
Description
pharmacology final
Updated