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Indirect Sympathomimetics
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Indirect sympathomimetics (8)
Amphetamine
Tyramine
Methylphenidate (Ritalin)
Dextgroamphetamine
Atomoxetine (Straterra)
Modafinil (Provigil)
Phentermine
Lisdexamfetamine
Amphetamine Therapeutic Use (3)
ADHD
Nacrolepsy
Obesity (short acting)
Amphetamine MOA (2)
Inhibits reuptake of DA and NE, more DA and NE available for transmission in prefrontal cortex
Reverses action of NET.
Amphetamines and noradrenergic pathway
Increases neurotransmission originating in locus coeruleus
Amphetamines in dopaminergic pathway
Enhances transmission in the ventral tegmental area, projecting to nucleuc accumbens (pleasure center)
Amphetamine adverse effects (4)
Restlessness
Insomnia
talkativeness
Headache
Amphetamine drug interactions (3)
Acidifying agents - increase urinary excretion
Alkalinizing agents - potentiate their effect
Tricyclic antidepressans - increase in [AMP] in brain, increased CV effects
Author
jaguavai
ID
120058
Card Set
Indirect Sympathomimetics
Description
Indirect Sympathomimetics
Updated
2011-12-01T15:54:55Z
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