Anticholinergics

Anticholinergic Drugs

Ipratropium bromide (Atrovent nasal spray)
Indication
- Second or third line treatment for allergic rhinitis.
- Useful for vasomotor rhinitis.
MoA
- Blocks the action of acetylcholine at parasympathetic sites in the mucosa
- Competes with acetylcholine for M3 receptor sites(anticholinergic, major), and binds nonselectively to M2 receptor sites(cholinergic, minor)
Onset of action

Rapid, several minutes
SEs
- Severe nasal drying
- Epistaxis
Contra

Hypersensitivity to the drug
Drug Interactions

Anticholinergics increase the effects.

Author

mpgcuenca

120030

Card Set

Anticholinergics

Description

Anticholinergics

Updated

2011-12-01T08:30:33Z

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