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1. What are the 5 major fxns of the liver?
- Metabolism &/or storage of fat, CHO, protein, vitamins, and minerals
- Blood volume reservoir (sponge)- distends/compresses to alter circulating blood volume
- Blood filter (bad for cancer)- helps purify blood
- Blood clotting factors- including prothrombin and fibrinogen
- Drug metabolism and detoxification
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2. Discuss LFTS: Liver Enzymes
- Composed of ALT, AST, and Alk Phos (all exist elsewhere)
- Abnormal trends are very increased
- (look for relationship with bilirubin for liver specific)
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3. Discuss LFTs: Bilirubin
- Two types: conjugated and unconjugated (circulates)
- too high (2 or above) results in Jaundice
- Abnormal is very elevated- results in abnormal extretion (Jaundice, clay stool, dark urine)
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4. Discuss LFTs: Serum Ammonia
- Nitrogen waste
- Abnml: Inc. Hepatoencephapopathy
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5. Discuss LFTs: Serum Protein and Serum albumin
Decrease b/c liver makea these products
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6. What happens to Prothrombin time with liver problems?
Prolonged due to coagulopathy problems
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7. What is the correlation with babies and jaundice?
Babies livers are not yet developed but do not always present with Jaundice
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