Lower GI

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Intestinal Gas therapy
- Simethacone
- a-Galactosaide
- Activated Charcoal
MOA of Simethacone

reduce surface tension of gas bubbles
MOA of a-Galactose

natural food enzyme hat breaks down complex carbs in gas producing foods
MOA if activated charcoal

absorbs intestinal gas
activated charcoal side effects
- vomiting
- hypersensitivity rxn
- black stool
simethacone dose

40-360mg po pc & hs prn
a-galactosidase dose

150mg po wf
activated charcoal dose
- 500-520mg po pc ( may repeat in 2 hours)
- 10g/day max
Hemorrhoids treatment
- Local anesthetics
- vasoconstrictors
- astringents
- corticosteroids
- protectants
- analgesic/anesthetic ( camphor)
Local anesthetics side effects
- contact dermatitis
- burning
- stinging
- hypersensitivity rxn
vasoconstrictor SE

HTN
Corticosteroids SE
- itching
- stinging
- hypersensitivity rxn
analgesic/anesthetic SE

contact exzema
Protectants SE
- skin sensitivity
- irritation
Protectants
- Al Hydroxide
- cocoa butter
- glycerin
- mineral oil
- white petrolatum
- shark liver oil
- zinc oxide
- topical starch
astringents
- witch hazel
- zinc oxide
Local Anesthetics
- benzocaine
- pamoxine
- dibucaine
Therapy for Constipation
- Bulk laxatives
- osmotic laxative
- lubricant laxative
- emollient/ stool softner
- stimulant laxatives
- saline laxatives
- misc. products
Bulk laxatives
- psyllium
- methylcellulose
- polycarbophil
- ( All first Line therapy)
Bulk Laxative SE
- abdominal cramps
- constipation
- flatulence
- esophageal
- bowel obstruction
Bulk Laxatives MOA

absorbs intestinal water, and forms a gel that promotes peristalsis and fecal elimination
Psyllium dose

2.5-3-gm/ day po in divided doses
methylcellulose

1-2gm po tid
Polycarbophil dose

1250mg po 1-4x/d
Osmotic Laxatives
- Glycerin(occasional us)
- Lactulose (Chronic use)
- polyethylene glycol 3350 (occasional us)
- polyethylene glycol-electolyte soln (bowel cleansing)
- sorbitol(occasional us)
Osmotic laxative SE
- flatulence
- abdominal cramping
- bloating
- dehydration
- electrolyte imbalance
Lubricant Laxatives

Mineral Oil (occasional constipation)
Lubricant laxatives SE
- abdominal cramps
- NVD
- decreased absorption of lipid soluble vitamins
- lipid pneumonia w/ aspiration
Emollient/stool softner drug

Docusate (Colase)- Preventative therapy
Emollient/ Stool Softener SE

electrolyte imbalance
Stimulant Laxatives
- Senna (exlax)
- Bisacodyl ( Dulcolax)
Stimulant LAxatives SE
- Abdominal cramping
- fluid & electrolyte imbalances
Saline laxative
- Sodium Phosphate ( Fleet Enema, Fleet Phosphosoda)
- MAgnesium CItrate ( Citroma)
- Magnesium Hydroxide ( Mik of Magnesia, Phillips)
MISC. Products
- Castor Oil
- Lubiprostone ( Amtiza)
Castor Oil SE
- Abdominal cramping
- fluid & electrolyte imbalances
Lubiprosterone ( Amtiza) SE
- N/D
- HA
- abdominal pain
Drugs used for Diarrhea
- Adsorbants
- -Polycarbophil
- Antimotility ( Acute and Chronic associated with IBD)
- -Loperamide
- Opiates ( Acute and Chronic)
- -Diphenoxylate/Atropine (Lomotil)
- -Difenoxin/Atropine (Motofen)
- -Paregoric
- -Opium Tincture
Antimotility Drugs SE
- dizziness
- constipation
Opiate SE
- drowsiness
- dizziness
- hypotension
- constipation
- respiratory depression
- physical dependence

Author

dagillam

11780

Card Set

Lower GI

Description

DSM exam 3

Updated

2010-03-24T02:28:20Z

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