MED-Lorazepam

Benzodiazepine

• -Most Potent Benzo
• -Intensifies GABA
• -Anxiolytic
• -Sedative
• -Muscle relaxant
• -Short-half life, good for pediatric seizures

• -Seizures (Status epilepticus)
• -Sedation prior to painful procedures
• -Anxiety

• -Hypersensitivity
• -Acute narrow-angle glaucoma
• -Coma
• -Shock
• -Acute alcohol intoxication

• -Renal or Hepatic impairment
• -Myasthenia gravis
• -COPD

• -Anterograde amnesia
• -Sedation
• -Hypertension OR Hypotension
• -Blurred vision
• -N/V
• -Confusion

• -Other CNS depressants
• -Alcohol
• -Cimetidine

ADULT

1-2 mg slow IVP or IM q 5 mins, max 8mg

PEDI

.1 mg/kg slow IVP or IM, max single does 2 mg. May repeat once after 5 mins

• Onset: 1-5 mins IV, 5-10 mins IM
• Half-Life: 10-20 hours