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Major minerals include: Ca, Mg, Na, K, __, __, __
P, S, Cl
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Factors which effect bioavailability of minerals include phytates, oxalates, ____ (found in teas), ___, ____ (found in wines), a person's needs & their ____ ____, and other minerals which compete for absorption
polyphenols, tannins, intestinal acidity
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Minerals regulations functions include:
___ balance, ___ balance
___ system function
muscle contraction
___ processes (____)
- Water, pH
- nervous
- metabolic; enzyme cofactors
-
2 electrolytes concentrated outside cell, 2 inside (and their charges)
- Outside: Na+, Cl-
- Inside: K+, P-
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Functions of sodium/potassium pump (3)
- Fluid balance
- Muscle contraction
- Conduction/transmission of nerve impulses
-
Functions of chloride include fluid balance and (3)
- Nerve impulse conduction
- HCl acid production
- Immune response
-
Ppl w/salt-sensitive hypertension are put on ___ diet
DASH
-
Sodium
AI:
UL:
DV:
- 1500 mg/dy
- 2300 mg/dy
- 2400 mg/dy
-
-
Ca + P crystals =
hydroxyapatite
-
Constituent of bone & teeth matrix
hydroxyapatite
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Functions of Ca include: bone & tooth structure (99%), nerve impulse transmission, muscle contraction, ___, and ___
blood clotting, metabolic rxns
-
3 hormones involved in maintainance of blood calcium levels
Parathyroid hormone (PTH), calcitriol (vit D), calcitonin
-
Stimulated when blood Ca is low and causes kidney retention of Ca, increases vit D activation, increases osteoclast activity (release Ca into blood by brkg down bone)
Parathyroid hormone (PTH)
-
Cells that break down bone to release Ca into blood
osteoclasts
-
Hormone which increases Ca absorption
Calcitriol (vit D)
-
When blood Ca is high, ___ is stimulated from thyroid, which inhibits osteoclasts
calcitonin
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When blood Ca is high ___ and ___ release decreases
PTH, calcitriol
-
Factors which increase Ca absorption include: vit D, lactose, optimal Ca:P ratio, ___, ____
- growth hormones
- meal, stomach acid
-
Factors which decreases Ca absorption include: aging, lack of vit D, high ___ intake combined w/low Ca intake, high __ intake (mineral), lack of ____, and lots of _(3)___ intake
- protein
- P
- stomach acid
- fiber, phytate, oxalate
-
Deficiency of Ca causes osteoporosis, ineffective ___, ____ which are muscle spasms
- blood clotting
- hypocalcemic tetany
-
Excess Ca intake increases risk of ___ type kidney stones & ___
- oxalate
- interference w/absorption of other minerals
-
Phsophorus important b/c part of essential compounds (ATP, phospholipids, DNA, RNA), Bone structure (hydroxyapatite), and for ____
pH control
-
Sources of P
Dairy, grains, meat, processed foods
-
Magnesium is important for bone health, activates ___, is ____, and plays a role in ___(3)___ function
- ATP, enzyme cofactor
- nerve, lung, cardiac
-
Sources Mg
Plants, "hard" water
-
Effects of deficient Mg include hypertension, heart attack; ___2___; develops slowly & alcoholics at risk
- irregular heartbeat
- weakness, muscle pain
-
Effects of excess Mg (3)
- Weakness, nausea
- Kidney failure
-
Structure of bone is:
__/__ mineral (hydroxyapatite = ___ + ___)
__/__ water and protein (___)
-
___ build bone
___ break down bone
-
Calcitonin vs PTH
- Calcitonin inhibits Ca release from bone
- PTH increases Ca release from bone
-
Normal BP: <
Prehypertension:
Hypertension: >
- 120/80
- 120-139 / 80-89
- 139/89
-
Risk factors for hypertension include obesity, excess salt intake, lack exercise, excess alcohol, fam history, increasing age, and ___ have it more than ___ (races)
African American, Caucasian
-
Increasing potassium intake can help those with ___
hypertension
-
One strategy to reduce risk of osteoporosis is to maximize ___
peak bone mass
-
One serving of dairy supplies ~ ___ mg Ca
300
-
When choosing Ca supplements, look for ___ calcium levels
Ca ___ can be taken any time of day
Ca ___ should be taken w/meal (acid)
- elemental
- citrate
- carbonate
-
When choosing Ca supplements, look for ___ or ___ on labels, which have standards for quality, purity, & disintegration of tablets
- USP (United States Pharmocopeia)
- CL (Consumer Lab)
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