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mouth
responsible for ingestion , mastication and deglutition
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salivary glands
produce a fluid in the mouth that helps cleanse the mouth and teeth and that lubricates, dissolves , and begins the chemical breakdown
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tongue
forces the food to the back of the mouth for swallowing , places food in contact with the teeth
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colon
forms a semisolid waste material through haustral churning and peristalsis
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pharynx
passageway for food , fluid , and air , involved in deglutition
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teeth
composed of enamel , dentin , and pulp cavity , used in mastication
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pancreas
contain acini that release juices containing several digestive enzymes for protein , carbohydrate , lipid , and nucleic acid digestion and sodium bicarbonate to buffer stomach acid
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gallbladder
storage area for bile
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stomach
responsible for churning , peristalsis , storage and chemical digestion with the enzyme
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ileum
contains aggregated lymphatic follicles ( Peyer's patches ) in the mucosa
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liver
produced and secretes bile
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duodenum
contains duodenal ( Brunner's ) glands in the submucosa
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appendix
coiled tube attached to the cecum
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esophagus
collapsed , muscular tube involved in deglutition and peristalsis
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salivary amyase
an enzyme that initiates carbohydrate digestion in the mouth
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pancreatic lipase
the principal triglyceride-digesting enzyme in adults
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gastrin
stimulates secretion of gastric juices and promotes gastric emptying
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pepsin
secreted by chief cells in the stomach , a proteolytic enzyme
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bile
a nonenzymatic fat-emulsifying agent
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cholecystokinin
causes contraction of the gallbadder and stimulates the production of pancreatic juice rich in digestive enzymes
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lingual lipase
secreted by glands in the tongue, begins breakdown of triglycerides in the stomach
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brush border
microvilli of the small intestine that increase surface area for absorption , also contain some digestive enzymes
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villi
fingerlike projections of the mucosa of the small intestin that increase surface area for digestion and absorption
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parietal cells
produce hydrochloric acid and intrinsic factor in the stomach
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G cells
stomach enteroendocrine cells that secrete gastrin
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taniae coil
longitudianl muscular bands in the large intestine , tonic contractions produce haustra
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lacteal
lymphatic capillary used for chylomicron absorption in the small intestine
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Peyer's patches
groups of lymphatic nodules in the small intestine
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enteric nervous system
controls the GI tract motility and secretions of GI tract organs
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rugae
large mucosal folds in the stomach
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chief cells
secrete pepsinogen and gastric lipase in the stomach
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oxidation
the removal of electrons for m an atom or molecule resulting in a decrease in potential energy
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greater omentum
- - attachments to stomach and duodenum
- - drapes downward over coils of small intestine
- - then turns upward and attaches to transverse colon
- - contains a considerable amount of adipose tissue
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falciform ligament
attaches liver to anterior abdominal wall and diaphram
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less omentum
suspends stomach and duodenum from liver
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mesentery
binds jejunum and ileum to posterior abdominal wall
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mesocolon
binds transverse colon and sigmoid colon to posterior abdominla wall
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mouth
- - oral or buccal cavity
- - formed by cheeks , hard and soft palates , and tongue
- - palate separates oral cavity from nasal cavity
- - makes it possible to chew and breathe at the same time
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salivary glands secrete saliva
- - ordinarily just enough is secreted to keep mouth and pharynx moist and clean
- - when food enter mouth , secretion increases to lubricate , dissolve and begin chemical digestion
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3 pairs of major salivary glands secrete most of the saliva
- - parotid
- - submandibular
- - sublingual
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saliva
- - mostly water
- - provides a medium for dissolving food
- - solutes include : ions , dissovled gases , urea , uric acid , mucus, immunogloblulin A , lysozyme , and salivary amylase acts of starch
- - not all salivary glands produce the same saliva
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salivation
- - controlled by autonomic nervous system
- - parasympathetic stimulation promotes continuous secretion of moderate amoutn of saliva
- - chemical in food stimulates heavy secretion of saliva sympathetic decreases salivation
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tongue
- - accessory digestive organ
- - skeletal muscle covered by mucous membrane
- - maneuvers food for chewing , shapes food into a rounded mass , forces food back for swallowing
- - lingual glands secrete lingula lipase: act on triglycerides
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teeth or dentes
- - accessory digestive organ
- - periodontal ligament anchors teeth to walls of alveolar sockets
- - three major regions: crown , root , and neck
- - dentin forms majority of tooth: calcified connective tissue , dentin of crown covered by enamel , root covered by cementum
- - pulp cavity enclosed by dentin: contains pulp ( blood vessels , nerves , and lymphatic vessels )
- - incisors , cuspids ( canines ) premolars , molars
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2 dentitions ( set of teeth )
- - deciduous 20 teeth
- - permanent 32 teeth
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mechanical digestion in the mouth
- - chewing or mastication
- - food manipulated by tongue , ground by teeth , and mixed with saliva
- - foms bolus
- - soft , flexible , easily swallowed mass
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chemical digestion in the mouth
- - salivary amylase secrected by salivary glands acts on starches ( polysaccharides )
- - only monosaccharides can be absorbed into bloodstream
- - continues to act until inactivated by stomach acid
- - lingual lipase secreted by lingual glands of tongue acts on triglycerides
- - becomes activated in acidic environment of stomach
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pharynx
- - food passes from mouth into pharynx
- - 3 parts: nasopharynx , oropharynx , laryngopharynx
- - muscular contractions of pharynx propel food into esophagus
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nasopharynx
functions only in respiration
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oropharynx
digestive and respiratory functions
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laryngopharynx
digestive and respiratory functions
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esophagus
- - collapsible muscular tube , passes through esophageal hiatus ( opening in diaphragm )
- - secretes mucous and transports food
- - no enzymes produced no absorption
- - layers : mucosa - protection against wear and tear
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2 esophageal sphincter
- 1. upper esophageal sphincter ( UES ) : regulates movement from pharynx into esophagus
- 2. lower esophageal sphincter (LES ) : regulates movement from esophagus into stomach acid reflux
adventitia: attaches to surrounding structures
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stomach
- - serves as mixing chamber and holding reservoir
- - mixes saliva , food , and gastric juice to form chyme
- - forces a small quantity of chyme into intestine at appropriate interval
- - MOST distensible part of GI tract
- - in stomach : digestion of starch continues , digestion of proteins and triglycerides begins , the semisolid bolus os converted to a liquid
- - certain substances are absorbed
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4 main regions of the stomach
- 1. cardia
- 2. fundus
- 3. body
- 4. pylorus
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rugae
large folds of mucosa in the stomach
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layers of the stomach
- mucosa- gastric glands open into gastric pits
- - three types of exocrine gland cells produce gastric juice
- . mucous neck cells- secrete mucus
- . parietal cells- secrete intrinsic factor and HCL
- . chief cells- endocrine cell secrete gastrin
- submucosa
- muscularis - additional inner oblique muscle layer
- serosa - part of visceral peritoneum
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mechanical digestion
- - mixing waves
- - gentle , rippling peristaltic movements
- - macerate food and mix it with gastric juice creating chyme
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chemical digestion
- - food may remain in fundus for about an hour without mixing with gastric juice
- - digestion by salivary amylase continues until inactivated by acidic gastric juice
- - acidic gastric juice activates lingual lipase
- - digest triglycerides into fatty acids and diglycerides
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parietal cells secrete
- H+ and CL- separately but net effect is HCL
- - HCL secretion is stimulated by: parasympathetic nervous system , gastrin secreted by G cells
- - trigged by histamine
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functions of HCL
- - kills many microbes
- - denatures proteins
- - stimulates secretions of hormones that promote flow of bile and pancreatic juice
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parietal cells also secrete intrinsic factor needed for
absorption of vitamin B12
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chief cells secrete
1. pepsinogen : is converted to pepsin when it comes in contact with HCL acid or active pepsin molecules , pepsin digests proteins
2. gastric lipase: splits triglycerides into fatty acids and monoglycerides
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mucous cells secrete
protect stomach epithelial cells from gastric juices , only allows for a small amount of nutrient absorption , some water , ions , short chain fatty acids , certain drugs ( aspirin ) and alcohol
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G cells secrete
- - Gastrin
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stimulates parietal cells to secrete HCL - - stimulates chief cells to secrete pepsinogen
- - contracts lower esophageal shincter
- - increases motility of the stomach
- - relaxes pyloric sphincter
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pancreas lies posterior to
- - lies posterior to greater curvature of stomach
- - connected to duodenum of small intestine by two ducts
1. pancreatic duct : joins common bile duct and becomes the hepatopancreatic ampulla , ampulla opens into duodenum at the major duodenal papilla
2. accessory duct : empties into duodenum superior to hepatopancreatic ampulla
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pancrease is made up of
- small clusters of glandular epithelial cells
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acini of pancreas form
- - exocrine portion of pancreas
- - secretes pancreatic juice
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pancreatic islets ( islets of langerhans ) form
- - form endocrine portion of pancreas
- - secrete hormones glucogon , insulin , somatostatin and pancreatic polypeptide
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pancreatic juice consist of
- - water
- - some salts
- - sodium bicarbonate: buffers acidic gastric juice in chyme , stops action of pepsin
- - enzymes : pancreatic amylase digest starch
- - trypsinogen : converted to trypsin when reaches lumen of small intestine , trypsin inhibitor secreted by acinar cells to combine with any trypsin formed accidentally in pancreas of pancreatic juice / digest protein
- - pancreatic lipase : the principal triglyceride-digesting enzyme
- - ribonuclease and deoxyribonuclease : digest nucleic acids
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